Search Results - "Yin Chun Chan"

Specific Binding of a d‐RNA G‐Quadruplex Structure with an l‐RNA Aptamer by Chan, Chun‐Yin, Kwok, Chun Kit

“…G‐quadruplex (G4) structures are of general importance in chemistry and biology, such as in biosensing, gene regulation, and cancers. Although a large…”
Get full text

A prebiotically plausible scenario of an RNA–peptide world by Müller, Felix, Escobar, Luis, Xu, Felix, Węgrzyn, Ewa, Nainytė, Milda, Amatov, Tynchtyk, Chan, Chun‐Yin, Pichler, Alexander, Carell, Thomas

“…The RNA world concept 1 is one of the most fundamental pillars of the origin of life theory 2 – 4 . It predicts that life evolved from increasingly complex…”
Get full text

G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications by Umar, Mubarak I, Ji, Danyang, Chan, Chun-Yin, Kwok, Chun Kit

“…Guanine (G)-quadruplexes (G4s) are unique nucleic acid structures that are formed by stacked G-tetrads in G-rich DNA or RNA sequences. G4s have been reported…”
Get full text

Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA‐Peptide World by Nainytė, Milda, Müller, Felix, Ganazzoli, Giacomo, Chan, Chun‐Yin, Crisp, Antony, Globisch, Daniel, Carell, Thomas

“…Fossils of extinct species allow us to reconstruct the process of Darwinian evolution that led to the species diversity we see on Earth today. The origin of…”
Get full text

Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures by Chan, Chun-Yin, Umar, Mubarak I, Kwok, Chun Kit

“…Here we investigate and reveal the effect of bulge position and bulge identity on G-quadruplexes using label-free spectroscopic techniques. Notably, we report…”
Get more information

A retrospective analysis on the management of pigmented lesions using a picosecond 755-nm alexandrite laser in Asians by Chan, Johnny Chun-yin, Shek, Samantha Yee-nam, Kono, Taro, Yeung, Chi Keung, Chan, Henry Hin-lee

“…Background and objectives Photo‐aging in Chinese often presents with benign pigmentary lesions. Q‐switched lasers for pigmentary lesions in Asians had reported…”
Get full text

Structural analysis and cellular visualization of APP RNA G-quadruplex by Lyu, Kaixin, Chen, Shuo-Bin, Chan, Chun-Yin, Tan, Jia-Heng, Kwok, Chun Kit

“…RNA G-quadruplexes (rG4s) are emerging structural motifs that are of pivotal importance in chemistry and biology; however, the current structural information…”
Get full text

HLA-B58:01 screening to prevent allopurinol-induced severe cutaneous adverse reactions in Chinese patients with chronic kidney disease by Wong, Christina Sze-Man, Yeung, Chi-Keung, Chan, Chun-Yin, Yap, Desmond Yat-Hin, Tang, Sydney Chi-Wai, Cheung, Bernard Man-Yung, Kwok, Janette Siu-Yin, Chan, Henry Hin-Lee

“…Human leukocyte antigen (HLA)-B*58:01 allele is a significant risk factor for allopurinol-induced severe cutaneous adverse reactions (SCARs) which is…”
Get full text

Be Still and You Will Know: A Mixed-Method Study on Solitude and Consideration of Future Consequences Among Youth in Rehabilitation by Poon, Cyanea Y. S., Chan, Christian S., Chau, Pauline P. L., Chan, Chun-Yin

“…Although solitude is found to be undesirable to many, systematic practice of it can yield positive psychological outcomes. This mixed-method study explored the…”
Get full text

Nasal prevention of SARS-CoV-2 infection by intranasal influenza-based boost vaccination in mouse models by Zhou, Runhong, Wang, Pui, Wong, Yik-Chun, Xu, Haoran, Lau, Siu-Ying, Liu, Li, Mok, Bobo Wing-Yee, Peng, Qiaoli, Liu, Na, Woo, Kin-Fai, Deng, Shaofeng, Tam, Rachel Chun-Yee, Huang, Haode, Zhang, Anna Jinxia, Zhou, Dongyan, Zhou, Biao, Chan, Chun-Yin, Du, Zhenglong, Yang, Dawei, Au, Ka-Kit, Yuen, Kwok-Yung, Chen, Honglin, Chen, Zhiwei

“…Vaccines in emergency use are efficacious against COVID-19, yet vaccine-induced prevention against nasal SARS-CoV-2 infection remains suboptimal. Since mucosal…”
Get full text

Mitochondrial regulation of acute extrafollicular B‐cell responses to COVID‐19 severity by Cao, Tianyu, Liu, Li, To, Kelvin Kai‐Wang, Lim, Chun‐Yu, Zhou, Runhong, Ming, Yue, Kwan, Ka‐Yi, Yu, Sulan, Chan, Chun‐Yin, Zhou, Biao, Huang, Haode, Mo, Yufei, Du, Zhenglong, Gong, Ruomei, Yat, Luk‐Tsz, Hung, Ivan Fan‐Ngai, Tam, Anthony Raymond, To, Wing‐Kin, Leung, Wai‐Shing, Chik, Thomas Shiu‐Hong, Tsang, Owen Tak‐Yin, Lin, Xiang, Song, You‐qiang, Yuen, Kwok‐Yung, Chen, Zhiwei

“…Background Patients with COVID‐19 display a broad spectrum of manifestations from asymptomatic to life‐threatening disease with dysregulated immune responses…”
Get full text

Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population by Yu, Mullin Ho Chung, Chan, Marcus Chun Yin, Chung, Claudia Ching Yan, Li, Andrew Wang Tat, Yip, Chara Yin Wa, Mak, Christopher Chun Yu, Chau, Jeffrey Fong Ting, Lee, Mianne, Fung, Jasmine Lee Fong, Tsang, Mandy Ho Yin, Chan, Joshua Chun Ki, Wong, Wilfred Hing Sang, Yang, Jing, Chui, William Chun Ming, Chung, Patrick Ho Yu, Yang, Wanling, Lee, So Lun, Chan, Godfrey Chi Fung, Tam, Paul Kwong Hang, Lau, Yu Lung, Tang, Clara Sze Man, Yeung, Kit San, Chung, Brian Hon Yin

“…Preemptive pharmacogenetic testing has the potential to improve drug dosing by providing point-of-care patient genotype information. Nonetheless, its…”
Get full text

Development of RNA G-quadruplex (rG4)-targeting l-RNA aptamers by rG4-SELEX by Umar, Mubarak I., Chan, Chun-Yin, Kwok, Chun Kit

“…RNA G-quadruplex (rG4)-SELEX is a method that generates l -RNA aptamers to target an rG4 structure of interest, which can be applied to inhibit…”
Get full text

A Cancer Cell-Selective and Low-Toxic Bifunctional Heterodinuclear Pt(IV)–Ru(II) Anticancer Prodrug by Ma, Lili, Lin, Xudong, Li, Cai, Xu, Zoufeng, Chan, Chun-Yin, Tse, Man-Kit, Shi, Peng, Zhu, Guangyu

“…Although different types of metal-based anticancer complexes have been synthesized, novel complexes to reduce the serious side effect of cisplatin and conquer…”
Get full text

Proteomic and Transcriptome Profiling of G‑Quadruplex Aptamers Developed for Cell Internalization by Zhang, Yang, Wu, Yang, Zheng, Hongjin, Xi, Hui, Ye, Taoyu, Chan, Chun-Yin, Kwok, Chun Kit

“…Nucleic acid medicine is expected to be among the most promising next-generation therapies. Applications of nucleic acid in vivo are still challenging as a…”
Get full text

Techno-Economic Analysis of Solid Oxide Fuel Cell-Gas Turbine Hybrid Systems for Stationary Power Applications Using Renewable Hydrogen by Chan, Chun, Rosner, Fabian, Samuelsen, Scott

“…Solid oxide fuel cell (SOFC)–gas turbine (GT) hybrid systems can produce power at high electrical efficiencies while emitting virtually zero criteria…”
Get full text

Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies by Zhou, Dongyan, Chan, Jasper Fuk-Woo, Zhou, Biao, Zhou, Runhong, Li, Shuang, Shan, Sisi, Liu, Li, Zhang, Anna Jinxia, Chen, Serena J., Chan, Chris Chung-Sing, Xu, Haoran, Poon, Vincent Kwok-Man, Yuan, Shuofeng, Li, Cun, Chik, Kenn Ka-Heng, Chan, Chris Chun-Yiu, Cao, Jianli, Chan, Chun-Yin, Kwan, Ka-Yi, Du, Zhenglong, Lau, Thomas Tsz-Kan, Zhang, Qi, Zhou, Jie, To, Kelvin Kai-Wang, Zhang, Linqi, Ho, David D., Yuen, Kwok-Yung, Chen, Zhiwei

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by a burst in the upper respiratory portal for high transmissibility. To…”
Get full text

Centralized Regulation Scheme for a Parallel-Mode Switched-Capacitor Converter System With Simple Unit Commitment by Yat Chi Fong, Cheng, Ka Wai Eric, Yuanmao Ye, Yin Chun Chan

“…Novel load regulation methods for switched-capacitor converter (SCC) system operating in parallel mode are proposed. SCCs are ready for integrated design which…”
Get full text

Validation of evidence-based questionnaire for TCM syndrome differentiation of heart failure and evaluation of expert consensus by Leung, Alice Yeuk Lan, Zhang, Jialing, Chan, Chun Yin, Chen, Xiaotong, Mao, Jingyuan, Jia, Zhenhua, Li, Xinli, Shen, Jiangang

“…Traditional Chinese Medicine (TCM) is widely used to treat heart failure (HF). Syndrome differentiation is a unique and crucial component in TCM practice for…”
Get full text

Specific Binding of a d‐RNA G‐Quadruplex Structure with an l‐RNA Aptamer by Chan, Chun‐Yin, Kwok, Chun Kit

“…G‐quadruplex (G4) structures are of general importance in chemistry and biology, such as in biosensing, gene regulation, and cancers. Although a large…”
Get full text