Search Results - "Yin, Zhinan"

Controlling Cytokine Storm Is Vital in COVID-19 by Tang, Lu, Yin, Zhinan, Hu, Yu, Mei, Heng

“…Corona virus disease 2019 (COVID-19) has caused a global outbreak and severely posed threat to people's health and social stability. Mounting evidence suggests…”
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Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation by Wang, Shuo, Xia, Pengyan, Chen, Yi, Qu, Yuan, Xiong, Zhen, Ye, Buqing, Du, Ying, Tian, Yong, Yin, Zhinan, Xu, Zhiheng, Fan, Zusen

“…An emerging family of innate lymphoid cells (termed ILCs) has an essential role in the initiation and regulation of inflammation. However, it is still unclear…”
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Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegans by Wan, Qin-Li, Meng, Xiao, Wang, Chongyang, Dai, Wenyu, Luo, Zhenhuan, Yin, Zhinan, Ju, Zhenyu, Fu, Xiaodie, Yang, Jing, Ye, Qunshan, Zhang, Zhan-Hui, Zhou, Qinghua

“…As a major risk factor to human health, obesity presents a massive burden to people and society. Interestingly, the obese status of parents can cause progeny’s…”
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Vitamin C promotes the proliferation and effector functions of human γδ T cells by Kouakanou, Léonce, Xu, Yan, Peters, Christian, He, Junyi, Wu, Yangzhe, Yin, Zhinan, Kabelitz, Dieter

“…γδ T cells are of interest as effector cells for cellular immunotherapy due to their HLA-non-restricted lysis of many different tumor cell types. Potential…”
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The inhibition of tumor growth and metastasis by self-assembled nanofibers of taxol by Wang, Huaimin, Wei, Jun, Yang, Chengbiao, Zhao, Huiyuan, Li, Dongxia, Yin, Zhinan, Yang, Zhimou

“…Abstract Molecular hydrogels have big potential for local delivery and sustained release of therapeutic agents. In this paper, we reported on a molecular…”
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The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis by Wang, Yifei, Tian, Qin, Hao, Yaxing, Yao, Wei, Lu, Jinjin, Chen, Cheng, Chen, Xiangyu, Lin, Yao, Huang, Qizhao, Xu, Lifan, Hu, Jianjun, Lei, Shun, Wei, Zhengping, Luo, Yuan, Li, Zhirong, Hu, Li, Tang, Jianfang, Wu, Qing, Zhou, Xinyuan, Wu, Yuzhang, Yin, Zhinan, Xu, Jianqing, Ye, Lilin

“…Antigen-specific memory CD4 + T cells can persist and confer rapid and efficient protection from microbial reinfection. However, the mechanisms underlying the…”
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γδ T cells provide the early source of IFN-γ to aggravate lesions in spinal cord injury by Sun, Guodong, Yang, Shuxian, Cao, Guangchao, Wang, Qianghua, Hao, Jianlei, Wen, Qiong, Li, Zhizhong, So, Kwok-Fai, Liu, Zonghua, Zhou, Sufang, Zhao, Yongxiang, Yang, Hengwen, Zhou, Libing, Yin, Zhinan

“…Immune responses and neuroinflammation are critically involved in spinal cord injury (SCI). γδ T cells, a small subset of T cells, regulate the inflammation…”
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Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer by Xu, Yan, Xiang, Zheng, Alnaggar, Mohammed, Kouakanou, Léonce, Li, Jiawei, He, Junyi, Yang, Jiashuang, Hu, Yi, Chen, Yan, Lin, Li, Hao, Jianlei, Li, Jingxia, Chen, Jibing, Li, Man, Wu, Qingling, Peters, Christian, Zhou, Qinghua, Li, Jianshuang, Liang, Yingqing, Wang, Xiaohua, Han, Baohui, Ma, Meili, Kabelitz, Dieter, Xu, Kecheng, Tu, Wenwei, Wu, Yangzhe, Yin, Zhinan

“…Vγ9Vδ2 T cells are promising candidates for cellular tumor immunotherapy. Due to their HLA-independent mode of action, allogeneic Vγ9Vδ2 T cells can be…”
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Loss of fragile site-associated tumor suppressor promotes antitumor immunity via macrophage polarization by Zhang, Lijuan, Zhang, Kai, Zhang, Jieyou, Zhu, Jinrong, Xi, Qing, Wang, Huafeng, Zhang, Zimu, Cheng, Yingnan, Yang, Guangze, Liu, Hongkun, Guo, Xiangdong, Zhou, Dongmei, Xue, Zhenyi, Li, Yan, Zhang, Qi, Da, Yurong, Liu, Li, Yin, Zhinan, Yao, Zhi, Zhang, Rongxin

“…Common fragile sites (CFSs) are specific breakage-prone genomic regions and are present frequently in cancer cells. The (E2-independent) E3…”
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AIM2 Facilitates the Apoptotic DNA-induced Systemic Lupus Erythematosus via Arbitrating Macrophage Functional Maturation by Zhang, Weijuan, Cai, Yanxing, Xu, Wei, Yin, Zhinan, Gao, Xiaoming, Xiong, Sidong

“…Purpose Lupus nephritis, a major cause of morbidity in patients with systemic lupus erythematosus (SLE), is generally thought to be induced by…”
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γδ T cells: origin and fate, subsets, diseases and immunotherapy by Hu, Yi, Hu, Qinglin, Li, Yongsheng, Lu, Ligong, Xiang, Zheng, Yin, Zhinan, Kabelitz, Dieter, Wu, Yangzhe

“…The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and hyperactivation, highlights the potential of immune renormalization…”
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The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice by Tang, Wei, Lu, Yi, Tian, Qing-Yun, Zhang, Yan, Guo, Feng-Jin, Liu, Guang-Yi, Syed, Nabeel Muzaffar, Lai, Yongjie, Lin, Edward Alan, Kong, Li, Su, Jeffrey, Yin, Fangfang, Ding, Ai-Hao, Zanin-Zhorov, Alexandra, Dustin, Michael L., Tao, Jian, Craft, Joseph, Yin, Zhinan, Feng, Jian Q., Abramson, Steven B., Yu, Xiu-Ping, Liu, Chuan-ju

“…The growth factor progranulin (PGRN) has been implicated in embryonic development, tissue repair, tumorigenesis, and inflammation, but its receptors remain…”
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Cell type specific IL-27p28 (IL-30) deletion in mice uncovers an unexpected regulatory function of IL-30 in autoimmune inflammation by Kim, Dongkyun, Kim, Sohee, Kang, Myung-su, Yin, Zhinan, Min, Booki

“…IL-27 is an IL-12 family cytokine with immune regulatory properties, capable of modulating inflammatory responses, including autoimmunity. While extensive…”
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Normalization cancer immunotherapy: blocking Siglec-15 by Cao, Guangchao, Xiao, Zhiqiang, Yin, Zhinan

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Allogenic Natural Killer Cell Immunotherapy Combined with Irreversible Electroporation for Stage IV Hepatocellular Carcinoma: Survival Outcome by Alnaggar, Mohammed, Lin, Mao, Mesmar, Adnan, Liang, Shuzhen, Qaid, Ammar, Xu, Kecheng, Chen, Jibing, Niu, Lizhi, Yin, Zhinan

“…Abstract Background/Aims: We evaluated the clinical effectiveness of irreversible electroporation (IRE) in combination with immunotherapy using allogenic…”
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Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice by Dong, Yingying, Geng, Yan, Li, Lian, Li, Xiaohe, Yan, Xiaohua, Fang, Yinshan, Li, Xinxin, Dong, Siyuan, Liu, Xue, Li, Xue, Yang, Xiuhong, Zheng, Xiaohong, Xie, Ting, Liang, Jiurong, Dai, Huaping, Liu, Xinqi, Yin, Zhinan, Noble, Paul W, Jiang, Dianhua, Ning, Wen

“…Progressive tissue fibrosis is a cause of major morbidity and mortality. Pulmonary fibrosis is an epithelial-mesenchymal disorder in which TGF-β1 plays a…”
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Irreversible electroporation plus allogenic Vγ9Vδ2 T cells enhances antitumor effect for locally advanced pancreatic cancer patients by Lin, Mao, Zhang, Xiaoyan, Liang, Shuzhen, Luo, Haihua, Alnaggar, Mohammed, Liu, Aihua, Yin, Zhinan, Chen, Jibing, Niu, Lizhi, Jiang, Yong

“…Immunotherapy has limited efficacy against locally advanced pancreatic cancer (LAPC) due to the presence of an immunosuppressive microenvironment (ISM)…”
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IL-1β-activated mTORC2 promotes accumulation of IFN-γ+ γδ T cells by upregulating CXCR3 to restrict hepatic fibrosis by Liu, Qihui, Yang, Quanli, Wu, Zengfeng, Chen, Yanfang, Xu, Miaomiao, Zhang, Hua, Zhao, Jiliang, Liu, Zonghua, Guan, Zerong, Luo, Jing, Li, Zhi-yong, Sun, Guodong, Wen, Qiong, Xu, Yan, Li, Zhenhua, Chen, Kebing, Ben, Xiaosong, He, Wanchun, Li, Xueshi, Yin, Zhinan, Hao, Jianlei, Lu, Ligong

“…Liver fibrosis represents a severe stage of liver damage, with hallmarks of inflammation, hepatic stellate cell activation, and extracellular matrix…”
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High-sensitive sensory neurons exacerbate rosacea-like dermatitis in mice by activating γδ T cells directly by Zhang, Yiya, Li, Tao, Zhao, Han, Xiao, Xin, Hu, Ximin, Wang, Ben, Huang, Yingxue, Yin, Zhinan, Zhong, Yun, Li, Yangfan, Li, Ji

“…Rosacea patients show facial hypersensitivity to stimulus factors (such as heat and capsaicin); however, the underlying mechanism of this hyperresponsiveness…”
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Roles of mTORC1 and mTORC2 in controlling γδ T1 and γδ T17 differentiation and function by Yang, Quanli, Liu, Xia, Liu, Qihui, Guan, Zerong, Luo, Jing, Cao, Guangchao, Cai, Ruitian, Li, Zhenhua, Xu, Yan, Wu, Zengfeng, Xu, Miaomiao, Zhang, Song, Zhang, Fan, Yang, Hengwen, Lin, Xuejia, Yang, Meixiang, Wu, Yangzhe, Gao, Yunfei, Flavell, Richard, Hao, Jianlei, Yin, Zhinan

“…The metabolism-controlled differentiation of αβ T cells has been well documented; however, the role of a metabolism program in γδ T cell differentiation and…”
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