Search Results - "Yin, Xianzhen"
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1
The Angiogenic Effect of microRNA-21 Targeting TIMP3 through the Regulation of MMP2 and MMP9
Published in PloS one (12-02-2016)“…microRNAs are a novel set of small, non-protein-coding nucleotide RNAs that negatively regulate the expression of target mRNAs. miRNA-21 is a microRNA that is…”
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2
Multiscale modelling of cerebrovascular injury reveals the role of vascular anatomy and parenchymal shear stresses
Published in Scientific reports (21-06-2021)“…Neurovascular injury is often observed in traumatic brain injury (TBI). However, the relationship between mechanical forces and vascular injury is still…”
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3
A combinatorial method to visualize the neuronal network in the mouse spinal cord: combination of a modified Golgi-Cox method and synchrotron radiation micro-computed tomography
Published in Histochemistry and cell biology (01-04-2021)“…Exploring the three-dimensional (3D) morphology of neurons is essential to understanding spinal cord function and associated diseases comprehensively. However,…”
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4
High-Resolution Digital Panorama of Multiple Structures in Whole Brain of Alzheimer's Disease Mice
Published in Frontiers in neuroscience (19-04-2022)“…Simultaneously visualizing Amyloid-β (Aβ) plaque with its surrounding brain structures at the subcellular level in the intact brain is essential for…”
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5
The structural diversity of ibuprofen sustained-release pellets on the same goal of bioequivalence consistency
Published in Materials & design (01-05-2022)“…[Display omitted] •Realization of static and dynamic structural diversities of ibuprofen sustained-release pellets using Micro-computed tomography on the goal…”
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6
Visualization and quantitative profiling of mixing and segregation of granules using synchrotron radiation X-ray microtomography and three dimensional reconstruction
Published in International journal of pharmaceutics (10-03-2013)“…Tomographic imaging techniques have great potential for improving understanding of the dynamics of granular materials during manufacturing, handling, and…”
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7
Fabrication of non-spherical Pickering emulsion droplets by cyclodextrins mediated molecular self-assembly
Published in Colloids and surfaces. A, Physicochemical and engineering aspects (05-02-2016)“…[Display omitted] •Non-spherical droplets were fabricated by cyclodextrins mediated self-assembly.•The non-sphericity of droplets could be…”
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8
Quantification of Swelling and Erosion in the Controlled Release of a Poorly Water-Soluble Drug Using Synchrotron X-ray Computed Microtomography
Published in The AAPS journal (01-10-2013)“…The hydration layer plays a key role in the controlled drug release of gel-forming matrix tablets. For poorly water-soluble drugs, matrix erosion is considered…”
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Microstructural investigation to the controlled release kinetics of monolith osmotic pump tablets via synchrotron radiation X-ray microtomography
Published in International journal of pharmaceutics (10-05-2012)“…Tomographic imaging techniques are attractive tools for the visualization of the internal structural characteristics of pharmaceutical solid dosage forms. In…”
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10
Non-destructive 3D Microtomography of Cerebral Angioarchitecture Changes Following Ischemic Stroke in Rats Using Synchrotron Radiation
Published in Frontiers in neuroanatomy (31-01-2019)“…A better understanding of functional changes in the cerebral microvasculature following ischemic injury is essential to elucidate the pathogenesis of stroke…”
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11
Redefinition to bilayer osmotic pump tablets as subterranean river system within mini-earth via three-dimensional structure mechanism
Published in Acta pharmaceutica Sinica. B (01-05-2022)“…Defining and visualizing the three-dimensional (3D) structures of pharmaceuticals provides a new and important tool to elucidate the phenomenal behavior and…”
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12
Multiscale Co‐reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution
Published in Advanced science (01-04-2021)“…The effective pulmonary deposition of inhaled particulate carriers loaded with drugs is a prerequisite for therapeutic effects of drug delivery via inhalation…”
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13
Bridging the structure gap between pellets in artificial dissolution media and in gastro-intestinal tract in rats
Published in Acta pharmaceutica Sinica. B (01-01-2022)“…Changes in structure of oral solid dosage forms (OSDF) elementally determine the drug release and its therapeutic effects. In this research, synchrotron…”
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14
Multi-dimensional visualization for the morphology of lubricant stearic acid particles and their distribution in tablets
Published in Asian journal of pharmceutical sciences (01-01-2020)“…The shapes of particles and their distribution in tablets, controlled by pretreatment and tableting process, determine the pharmaceutical performance of…”
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15
Optimization of taste-masking on ibuprofen microspheres with selected structure features
Published in Asian journal of pharmceutical sciences (01-03-2019)“…The microsphere was a primary particulate system for taste-masking with unique structural features defined by production process. In this article, ibuprofen…”
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16
Synchrotron radiation-based Fourier-transform infrared spectromicroscopy for characterization of the protein/peptide distribution in single microspheres
Published in Acta pharmaceutica Sinica. B (01-05-2015)“…The present study establishes a visualization method for the measurement of the distribution and localization of protein/peptide constituents within a single…”
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17
Three dimensional distribution of surfactant in microspheres revealed by synchrotron radiation X-ray microcomputed tomography
Published in Asian journal of pharmceutical sciences (01-07-2017)“…This study investigated the formulation mechanism of microspheres via internal surfactant distribution. Eudragit L100 based microspheres loaded with bovine…”
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18
Metal‐Organic Frameworks for Gene Therapy and Detection
Published in Advanced functional materials (01-03-2023)“…Gene therapy holds great promise as a biomedicine for treating cancer, viral infection, and recessive gene disorders, while genetic detection has been used for…”
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19
Macrophage phenotype switch by sequential action of immunomodulatory cytokines from hydrogel layers on titania nanotubes
Published in Colloids and surfaces, B, Biointerfaces (01-03-2018)“…[Display omitted] •A method to prepare immunoregulatory material was provided.•Rapid release of IFN-γ and sustained release of IL-4 were realized in…”
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20
An Enhanced Secure Authentication Scheme With One More Tag for RFID Systems
Published in IEEE sensors journal (01-08-2021)“…Currently, Radio Frequency Identification (RFID) is one of the key technologies to realize the Internet of Things (IoT), which is widely used in our daily…”
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