Search Results - "Yin, Weidong"
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1
Development of an inactivated vaccine candidate for SARS-CoV-2
Published in Science (American Association for the Advancement of Science) (03-07-2020)“…The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public…”
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2
Hepatitis A virus and the origins of picornaviruses
Published in Nature (London) (01-01-2015)“…Hepatitis A virus is a picornavirus that causes significant morbidity but remains poorly understood; this paper now provides high-resolution crystal structures…”
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3
A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71
Published in Nature structural & molecular biology (01-04-2012)“…Enterovirus 71 (EV71) is a major agent of hand, foot and mouth disease in children, but no vaccine or antiviral therapy is available. Structural analysis of…”
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4
Effect of Aging Temperature on the Microstructure and Mechanical Properties of a Novel β Titanium Alloy
Published in Materials (28-11-2023)“…High-strength metastable β titanium alloys are promising structural materials to be used in aviation industries. In order to achieve a high strength level,…”
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5
Ibrolipim attenuates early-stage nephropathy in diet-induced diabetic minipigs: Focus on oxidative stress and fibrogenesis
Published in Biomedicine & pharmacotherapy (01-09-2020)“…[Display omitted] •HSFD induces early-stage renal pathological and functional abnormalities in minipigs.•Nutrient stress promotes renal imbalance of oxidative…”
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6
Picornavirus uncoating intermediate captured in atomic detail
Published in Nature communications (03-06-2013)“…It remains largely mysterious how the genomes of non-enveloped eukaryotic viruses are transferred across a membrane into the host cell. Picornaviruses are…”
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7
Effectiveness of home-based exercise interventions on pain, physical function and quality of life in individuals with knee osteoarthritis: a systematic review and meta-analysis
Published in Journal of orthopaedic surgery and research (17-07-2023)“…The objective of the study was to evaluate the effectiveness of home-based exercise interventions on pain, physical function and quality of life in individuals…”
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Cohort profile: the Nanjing Diabetes Cohort database – a population-based surveillance cohort
Published in BMJ open (01-11-2024)“…Purpose To study epidemiology, complications, risk factors, clinical course and treatment patterns of diabetes, the Nanjing Diabetes Cohort (NDC) was…”
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Post-exposure prophylaxis with SA58 (anti-SARS-COV-2 monoclonal antibody) nasal spray for the prevention of symptomatic COVID-19 in healthy adult workers: a randomized, single-blind, placebo-controlled clinical study
Published in Emerging microbes & infections (01-12-2023)“…Monoclonal antibodies (mAbs) and the post-exposure prophylaxis (PEP) with mAbs represent a very important public health strategy against coronavirus disease…”
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10
Facies-controlled prediction of dolomite reservoirs in the Middle Permian Qixia Formation in Shuangyushi, northwestern Sichuan Basin
Published in Energy Geoscience (01-04-2024)“…The Middle Permian Qixia Formation in the Shuangyushi area, northwestern Sichuan Basin, develops shoal-facies dolomite reservoirs. To pinpoint promising…”
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11
Free-Vertex Tetrahedral Finite-Element Representation and Its Use for Estimating Density Distribution of Irregularly-Shaped Asteroids
Published in Aerospace (01-12-2021)“…In this article, we present a free-vertex tetrahedral finite-element representation of irregularly shaped small bodies, which provides an alternative solution…”
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12
Microstructure and mechanical properties of additively manufactured Ti–6Al–4V alloy based on large area, high-resolution EBSD mapping
Published in Journal of materials research and technology (01-11-2024)“…The laser direct energy deposition (L-DED) is well-suited for metal manufacturing, offering advantages of excellent performance, high precision, intricate…”
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13
Piromelatine, a novel melatonin receptor agonist, stabilizes metabolic profiles and ameliorates insulin resistance in chronic sleep restricted rats
Published in European journal of pharmacology (15-03-2014)“…Chronic sleep deprivation may speed the onset or increase the severity of age-related conditions such as Type 2 diabetes, high blood pressure and obesity…”
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14
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China
Published in The Lancet (British edition) (26-04-2008)“…Summary Background In December, 2007, a family cluster of two individuals infected with highly pathogenic avian influenza A (H5N1) virus was identified in…”
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Orbit Determination and Thrust Estimation for Noncooperative Target Using Angle-Only Measurement
Published in Space: science & technology (2023)“…The classical interactive multimodel (IMM) algorithm has some disadvantages in tracking a noncooperative continuous thrust maneuvering spacecraft, such as poor…”
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Human diploid MRC-5 cells exhibit several critical properties of human umbilical cord-derived mesenchymal stem cells
Published in Vaccine (28-11-2014)“…Abstract MRC-5 is the most common human diploid cell line used in production of viral vaccines; mesenchymal stem cells (MSCs) is a type of adult multipotent…”
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17
Fighting against infectious diseases in China
Published in Human vaccines (01-12-2011)“…Dr. Yin started his research on infectious disease prevention in the 1980s. In 1985, Dr. Yin sucessfully isolated the hepatitis A virus, after which, in 2002,…”
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Establishing China's national standards of antigen content and neutralizing antibody responses for evaluation of enterovirus 71 (EV71) vaccines
Published in Vaccine (06-12-2011)“…Highlights ► Standards of antigen and neutralizing antibody for new EV71 vaccine were developed. ► These standards meet the specifications of WHO. ► The…”
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A novel melatonin agonist Neu-P11 facilitates memory performance and improves cognitive impairment in a rat model of Alzheimer' disease
Published in Hormones and behavior (01-06-2013)“…Previous studies have shown that melatonin is implicated in modulating learning and memory processing. Melatonin also exerts neuroprotective activities against…”
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Comparative analysis of the immunogenicity and protective effects of inactivated EV71 vaccines in mice
Published in PloS one (28-09-2012)“…Enterovirus 71 (EV71) is the major causative agent of hand, foot, and mouth disease (HFMD). Three inactivated EV71 whole-virus vaccines of different strains…”
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