Search Results - "Yin, Mengyue"

Effects of a reminiscence therapy-involved program on anxiety, depression, and the quality of life in cancer patients: a meta-analysis of randomized controlled trials by Sun, Xingliang, Su, Wenlian, Yin, Mengyue, Xia, Ling

“…Reminiscence therapy is increasingly being utilized for cancer patients to address psychological pressure and enhance their quality of life. This meta-analysis…”
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Evolution of Business Intelligence: An Analysis from the Perspective of Social Network by Hu, Hanqing, Yin, Mengyue, Li, Jianling

“…Based on CiteSpace, Pajek and other software, this paper makes a visual analysis of the knowledge graph of the related literature of Business Intelligence and…”
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ON THE IMPACT OF REAL ESTATE PRICES ON THE DEVELOPMENT OF REGIONAL ECONOMY IN CHINA–AN ESTIMATION BASED ON PANEL QUANTILE REGRESSION MODEL by Zhang, Baili, Ma, Yadong, Yin, Mengyue, Li, Zhengxun

“…The paper analyzes the mechanism of real estate prices on economic development with panel quantile regression model. It is found that real estate prices can…”
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Prediction and validation of human hepatobiliary clearances and hepatic concentrations of transported drugs using the relative expression factor (REF) and PET imaging approaches by Yin, Mengyue (Melody), Balhara, Ankit, Marie, Solène, Tournier, Nicolas, Unadkat, Jashvant

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Is Protein‐Mediated Uptake Of Drugs By OATPs, Via Protein‐Lipid Interaction, A Real Phenomenon Or An Artifact? by Yin, Mengyue, Storelli, Flavia, Unadkat, Jashvant

“…There is considerable interest in the observation that OATP‐mediated transport is significantly increased in the presence of albumin or plasma proteins, a…”
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Is the Protein-Mediated Uptake of Drugs by Organic Anion Transporting Polypeptides a Real Phenomenon or an Artifact? by Yin, Mengyue, Storelli, Flavia, Unadkat, Jashvant D.

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Successful Prediction of Fetal Exposure to Dual BCRP/P‐gp Drug Substrates Using the Efflux Ratio‐Relative Expression Factor Approach and PBPK M&S by Balhara, Ankit, Yin, Mengyue, Unadkat, Jashvant D.

“…To inform fetal drug safety, it is important to determine or predict fetal drug exposure throughout pregnancy. The former is not possible in the first or…”
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Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes Is Confounded by the Residual Statin-Protein Complex by Yin, Mengyue, Ishida, Kazuya, Liang, Xiaomin, Lai, Yurong, Unadkat, Jashvant D.

“…Inclusion of plasma (or plasma proteins) in human hepatocyte uptake studies narrows, but does not close, the gap in in vitro to in vivo extrapolation (IVIVE)…”
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Prediction of Transporter-Based Drug Clearances and Tissue Concentrations: Relative Expression Factor Approach and Protein-Mediated Uptake Effect by Yin, Mengyue

“…Clinical drug development often fails due to insufficient efficacy and safety, which can be attributed to not reaching the desired drug concentrations at their…”
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Successful Prediction of Human Hepatic Concentrations of Transported Drugs Using the Proteomics‐Informed Relative Expression Factor Approach by Yin, Mengyue, Balhara, Ankit, Marie, Solène, Tournier, Nicolas, Gáborik, Zsuzsanna, Unadkat, Jashvant D.

“…Tissue drug concentrations determine the efficacy and toxicity of drugs. When a drug is the substrate of transporters that are present at the blood:tissue…”
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The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans by Storelli, Flavia, Yin, Mengyue, Kumar, Aditya R, Ladumor, Mayur K, Evers, Raymond, Chothe, Paresh P, Enogieru, Osatohanmwen J, Liang, Xiaomin, Lai, Yurong, Unadkat, Jashvant D

“…Predicting transporter-based drug clearance (CL) and tissue concentrations (TC) in humans is important to reduce the risk of failure during drug development…”
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Is The Protein-Mediated Uptake Of Drugs By OATPs A Real Phenomenon Or An Artifact? by Yin, Mengyue, Storelli, Flavia, Unadkat, Jashvant D

“…Plasma proteins or human serum albumin (HSA) have been reported to increase the intrinsic uptake clearance (CL ) of drugs by hepatocytes or organic anion…”
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Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach by Kumar, Vineet, Yin, Mengyue, Ishida, Kazuya, Salphati, Laurent, Hop, Cornelis E C A, Rowbottom, Christopher, Xiao, Guangqing, Lai, Yurong, Mathias, Anita, Chu, Xiaoyan, Humphreys, W Griffith, Liao, Mingxiang, Nerada, Zsuzsanna, Szilvásy, Nóra, Heyward, Scott, Unadkat, Jashvant D

“…Suspended, plated, or sandwich-cultured human hepatocytes are routinely used for in vitro to in vivo extrapolation (IVIVE) of transporter-mediated hepatic…”
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8-Methoxypsoralen disrupts MDR3-mediated phospholipids efflux and bile acid homeostasis and its relevance to hepatotoxicity by Zhao, Guolin, Xu, Dengqiu, Yuan, Ziqiao, Jiang, Zhenzhou, Zhou, Wang, Li, Zhijian, Yin, Mengyue, Zhou, Zhixing, Zhang, Luyong, Wang, Tao

“…Graphical abstract…”
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A China-Based Cost-Effectiveness Analysis of Novel Oral Anticoagulants versus Warfarin in Patients with Left Ventricular Thrombosis by Tian, Shuo, Zhong, Haitao, Yin, Mengyue, Jiang, Pei, Liu, Qiao

“…This study aims to conduct a comprehensive cost-effectiveness comparison between novel oral anticoagulants (NOACs) and warfarin in Chinese patients with left…”
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Interpretation of Protein-Mediated Uptake of Statins by Hepatocytes is Confounded by the R esidua l Statin-Protein Complex by Yin, Mengyue, Ishida, Kazuya, Liang, Xiaomin, Lai, Yurong, Unadkat, Jashvant D

“…Inclusion of plasma (or plasma proteins) in human hepatocyte uptake studies narrows, but does not close, the gap in to extrapolation (IVIVE) of organic anion…”
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