Search Results - "Yin, Jerry C.P."
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Autoreceptor Control of Peptide/Neurotransmitter Corelease from PDF Neurons Determines Allocation of Circadian Activity in Drosophila
Published in Cell reports (Cambridge) (30-08-2012)“…Drosophila melanogaster flies concentrate behavioral activity around dawn and dusk. This organization of daily activity is controlled by central circadian…”
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Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster
Published in Nature neuroscience (01-04-2002)“…Synaptic stimulation activates signal transduction pathways, producing persistently active protein kinases. PKMzeta is a truncated, persistently active isoform…”
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3
Memory Formation: Filling in the Gaps in Flies
Published in Current biology (24-05-2011)“…Research in Drosophila has many advantages for the study of complex behavior. Two studies identify a new role for chemical and electrical signaling in the…”
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Circadian rhythms and memory formation
Published in Nature reviews. Neuroscience (01-08-2010)“…Key Points The regulation of memory formation by circadian rhythms and/or time-of-day effects is phylogenetically conserved in many species — including…”
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Mg2+ Block of Drosophila NMDA Receptors Is Required for Long-Term Memory Formation and CREB-Dependent Gene Expression
Published in Neuron (Cambridge, Mass.) (07-06-2012)“…NMDA receptor (NMDAR) channels allow Ca2+ influx only during correlated activation of both pre- and postsynaptic cells; a Mg2+ block mechanism suppresses NMDAR…”
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Type 1 Equilibrative Nucleoside Transporter Regulates Ethanol Drinking Through Accumbal N -Methyl-D-Aspartate Receptor Signaling
Published in Biological psychiatry (1969) (01-06-2011)“…Background Mice lacking type 1 equilibrative nucleoside transporter (ENT1−/− ) exhibit increased ethanol-preferring behavior compared with wild-type…”
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Spatio-temporal in vivo recording of dCREB2 dynamics in Drosophila long-term memory processing
Published in Neurobiology of learning and memory (01-02-2015)“…•We have analyzed a new reporter that allows us to track dCREB2 activity in vivo, in real time after training that produces memory formation.•In certain brain…”
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GLD2 poly(A) polymerase is required for long-term memory
Published in Proceedings of the National Academy of Sciences - PNAS (23-09-2008)“…The formation of long-term memory is believed to require translational control of localized mRNAs. In mammals, dendritic mRNAs are maintained in a repressed…”
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Drug-induced epigenetic changes produce drug tolerance
Published in PLoS biology (01-10-2007)“…Tolerance to drugs that affect neural activity is mediated, in part, by adaptive mechanisms that attempt to restore normal neural excitability. Changes in the…”
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Total and activated creb protein levels differentially change in hippocampal sub-regions with age and correlate with behavioral performance
Published in Alzheimer's & dementia (01-07-2015)Get full text
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The Drosophila dCREB2 Gene Affects the Circadian Clock
Published in Neuron (Cambridge, Mass.) (01-04-1999)“…We report the role of dCREB2, the Drosophila homolog of CREB/CREM, in circadian rhythms. dCREB2 activity cycles with a 24 hr rhythm in flies, both in a…”
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Cytoplasmic to nuclear localization of fatty-acid binding protein correlates with specific forms of long-term memory in Drosophila
Published in Communicative & integrative biology (01-09-2011)“…We recently reported evidence implicating fatty-acid binding protein (Fabp) in the control of sleep and memory formation. We used Drosophila melanogaster to…”
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Adaptable doxycycline-regulated gene expression systems for Drosophila
Published in Gene (30-05-2001)“…We have engineered two new versions of the doxycycline (dox) inducible system for use in Drosophila. In the first system, we have used the ubiquitously…”
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Overexpression of CREB reduces CRE-mediated transcription: behavioral and cellular analyses in transgenic mice
Published in Molecular and cellular neuroscience (01-04-2004)“…The CREB transcription factor mediates neuronal plasticity in many systems, but the relationship between CREB levels and CRE-mediated transcription in…”
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Mg(2+) block of Drosophila NMDA receptors is required for long-term memory formation and CREB-dependent gene expression
Published in Neuron (Cambridge, Mass.) (07-06-2012)“…NMDA receptor (NMDAR) channels allow Ca(2+) influx only during correlated activation of both pre- and postsynaptic cells; a Mg(2+) block mechanism suppresses…”
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The clock gene period differentially regulates sleep and memory in Drosophila
Published in Neurobiology of learning and memory (01-09-2018)“…•Period mutants have differential time-of-day effects on memory.•Baseline sleep changes in period mutants do not predict memory alterations.•Training-induced…”
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Neurogenesis in the adult Drosophila brain
Published in Genetics (Austin) (02-10-2021)“…We describe the Drosophila central brain as a new model in which to investigate adult neurogenesis. Following injury, we observe a significant increase in the…”
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PKMζ Maintains Spatial, Instrumental, and Classically Conditioned Long-Term Memories
Published in PLoS biology (01-12-2008)“…How long-term memories are stored is a fundamental question in neuroscience. The first molecular mechanism for long-term memory storage in the brain was…”
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A robust activity marking system for exploring active neuronal ensembles
Published in eLife (23-09-2016)“…Understanding how the brain captures transient experience and converts it into long lasting changes in neural circuits requires the identification and…”
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Circadian disruption of memory consolidation in Drosophila
Published in Frontiers in systems neuroscience (22-03-2023)“…The role of the circadian system in memory formation is an important question in neurobiology. Despite this hypothesis being intuitively appealing, the…”
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