Search Results - "Yim, Peter D."

Diminished androgen levels are linked to irritable bowel syndrome and cause bowel dysfunction in mice by Rastelli, Daniella, Robinson, Ariel, Lagomarsino, Valentina N, Matthews, Lynley T, Hassan, Rafla, Perez, Kristina, Dan, William, Yim, Peter D, Mixer, Madison, Prochera, Aleksandra, Shepherd, Amy, Sun, Liang, Hall, Kathryn, Ballou, Sarah, Lembo, Anthony, Nee, Judy, Rao, Meenakshi

“…Functional gastrointestinal disorders (FGIDs) have prominent sex differences in incidence, symptoms, and treatment response that are not well understood…”
Get full text

Activation of an Endogenous Opsin 3 Light Receptor Mediates Photo-Relaxation of Pre-Contracting Late Gestation Human Uterine Smooth Muscle Ex Vivo by Yim, Peter D, Hyuga, Shunsuke, Wu, Amy D, Dan, William, Vink, Joy Y, Gallos, George

“…Spontaneous preterm birth (sPTB) remains a worldwide healthcare challenge. Preterm labor (PTL) is thought to be the largest reversible cause of sPTB, but…”
Get more information

Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling by Gallos, George, Yocum, Gene T, Siviski, Matthew E, Yim, Peter D, Fu, Xiao Wen, Poe, Michael M, Cook, James M, Harrison, Neil, Perez-Zoghbi, Jose, Emala, Sr, Charles W

“…The clinical need for novel bronchodilators for the treatment of bronchoconstrictive diseases remains a major medical issue. Modulation of airway smooth muscle…”
Get more information

Light-Mediated Inhibition of Colonic Smooth Muscle Constriction and Colonic Motility via Opsin 3 by Dan, William, Park, Ga Hyun, Vemaraju, Shruti, Wu, Amy D, Perez, Kristina, Rao, Meenakshi, Berkowitz, Dan E, Lang, Richard A, Yim, Peter D

“…Opsin photoreceptors outside of the central nervous system have been shown to mediate smooth muscle photorelaxation in several organs. We hypothesized that…”
Get full text

Anoctamin 1 antagonism potentiates conventional tocolytic-mediated relaxation of pregnant human uterine smooth muscle by Hyuga, Shunsuke, Parry, Robert C, Danielsson, Jennifer, Vink, Joy, Fu, Xiao Wen, Wu, Amy, Dan, William, Yim, Peter D, Gallos, George

“…Currently available tocolytic agents are not effective treatment for preterm labor beyond 48 h. A major reason is the development of maternal side effects…”
Get full text

Novel Expression of GABAA Receptors on Resistance Arteries That Modulate Myogenic Tone by Yim, Peter D, Gallos, George, Lee-Kong, Steven A, Dan, William, Wu, Amy D, Xu, Dingbang, Berkowitz, Dan E, Emala, Charles W

“…The clinical administration of GABAergic medications leads to hypotension which has classically been attributed to the modulation of neuronal activity in the…”
Get more information

An isolated retrograde-perfused newborn mouse heart preparation by Barajas, Matthew, Yim, Peter D., Gallos, George, Levy, Richard J.

“…The Langendorff-perfused model is a powerful tool to study biological responses in the isolated heart in the absence of confounders. The model has been adapted…”
Get full text

Airway Epithelial Cell Release of GABA is Regulated by Protein Kinase A by Danielsson, Jennifer, Zaidi, Sarah, Kim, Benjamin, Funayama, Hiromi, Yim, Peter D., Xu, Dingbang, Worgall, Tilla S., Gallos, George, Emala, Charles W.

“…Introduction γ-amino butyric acid (GABA) is not only the major inhibitory neurotransmitter in the central nervous system (CNS), but it also plays an important…”
Get full text

Stroke and mechanical thrombectomy in patients with COVID-19: technical observations and patient characteristics by Wang, Arthur, Mandigo, Grace K, Yim, Peter D, Meyers, Philip M, Lavine, Sean D

“…COVID-19 infections have been shown to be associated with a range of thromboembolic disease. To describe our endovascular experience in a consecutive series of…”
Get more information

Airway smooth muscle photorelaxation via opsin receptor activation by Yim, Peter D, Gallos, George, Perez-Zoghbi, Jose F, Zhang, Yi, Xu, Dingbang, Wu, Amy, Berkowitz, Dan E, Emala, Charles W

“…Nonvisual opsin (OPN) receptors have recently been implicated in blue light-mediated photorelaxation of smooth muscle in various organs. Since photorelaxation…”
Get more information

Chloride channel blockers promote relaxation of TEA-induced contraction in airway smooth muscle by Yim, Peter D., Gallos, George, Perez-Zoghbi, Jose F., Trice, Jacquelyn, Zhang, Yi, Siviski, Matthew, Sonett, Joshua, Sr., Charles W. Emala

“…Enhanced airway smooth muscle (ASM) contraction is an important component in the pathophysiology of asthma. We have shown that ligand gated chloride channels…”
Get full text

Opsin 3-G αs Promotes Airway Smooth Muscle Relaxation Modulated by G Protein Receptor Kinase 2 by Wu, Amy D, Dan, William, Zhang, Yi, Vemaraju, Shruti, Upton, Brian A, Lang, Richard A, Buhr, Ethan D, Berkowitz, Dan E, Gallos, George, Emala, Charles W, Yim, Peter D

“…Recently, we characterized blue light-mediated relaxation (photorelaxation) of airway smooth muscle (ASM) and implicated the involvement of opsin 3 (OPN3), an…”
Get full text

Novel expression of a functional glycine receptor chloride channel that attenuates contraction in airway smooth muscle by Yim, Peter D., Gallos, George, Xu, Dingbang, Zhang, Yi, Emala, Charles W.

“…ABSTRACT Airway smooth muscle (ASM) contraction is an important component of the pathophysiology of asthma. Taurine, an agonist of glycine receptor chloride…”
Get full text

Anesthetic Management for Endovascular Treatment of Stroke in Patients With Coronavirus Disease 2019: A Case Series by Sharma, Richa, Yim, Peter D., García, Paul S.

“…A significant number of patients with coronavirus disease 2019 develop strokes with large vessel obstructions that may require endovascular treatment for…”
Get full text

Functional expression of γ-amino butyric acid transporter 2 in human and guinea pig airway epithelium and smooth muscle by Zaidi, Sarah, Gallos, George, Yim, Peter D, Xu, Dingbang, Sonett, Joshua R, Panettieri, Jr, Reynold A, Gerthoffer, William, Emala, Charles W

“…γ-Amino butyric acid (GABA) is a primary inhibitory neurotransmitter in the central nervous system, and is classically released by fusion of synaptic vesicles…”
Get full text

Comparison of cell expression formats for the characterization of GABA(A) channels using a microfluidic patch clamp system by Chen, Qin, Yim, Peter D, Yuan, Nina, Johnson, Juliette, Cook, James M, Smith, Steve, Ionescu-Zanetti, Cristian, Wang, Zhi-Jian, Arnold, Leggy A, Emala, Charles W

“…Ensemble recording and microfluidic perfusion are recently introduced techniques aimed at removing the laborious nature and low recording success rates of…”
Get more information

Raf-1 kinase mediates adenylyl cyclase sensitization by TNF-alpha in human airway smooth muscle cells by Osawa, Yoko, Yim, Peter D, Xu, Dingbang, Panettieri, Reynold A, Emala, Charles W

“…Tumor necrosis factor (TNF)-alpha is a potent inflammatory cytokine implicated in the exacerbation of asthma. Chronic exposure to TNF-alpha has been reported…”
Get more information

Can We Find Better Bronchodilators to Relieve Asthma Symptoms? by Townsend, Elizabeth A., Yim, Peter D., Gallos, George, Emala, Charles W.

“…Bronchodilators are the first line therapy during acute asthmatic exacerbations to reverse airway obstruction primarily by relaxing airway smooth muscle. Only…”
Get full text

Diminished androgen levels are linked to irritable bowel syndrome and cause bowel dysfunction in mice by Rastelli, Daniella, Robinson, Ariel, Lagomarsino, Valentina N, Matthews, Lynley T, Hassan, Rafla, Perez, Kristina, Dan, William, Yim, Peter D, Mixer, Madison, Prochera, Aleksandra, Shepherd, Amy, Sun, Liang, Hall, Kathryn, Ballou, Sarah, Lembo, Anthony, Nee, Judy, Rao, Meenakshi

“…Functional gastrointestinal disorders (FGIDs) have prominent sex differences in incidence, symptoms, and treatment response that are not well understood…”
Get full text

Functional Expression of [gamma]-Amino Butyric Acid Transporter 2 in Human and Guinea Pig Airway Epithelium and Smooth Muscle by Zaidi, Sarah, Gallos, George, Yim, Peter D, Xu, Dingbang, Sonett, Joshua R, Panettieri, Reynold A, Gerthoffer, William, Emala, Charles W

“…γ-Amino butyric acid (GABA) is a primary inhibitory neurotransmitter in the central nervous system, and is classically released by fusion of synaptic vesicles…”
Get full text