Search Results - "Yilmaz, H"

SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells by Kiel, Mark J., Yilmaz, Ömer H., Iwashita, Toshihide, Yilmaz, Osman H., Terhorst, Cox, Morrison, Sean J.

“…To improve our ability to identify hematopoietic stem cells (HSCs) and their localization in vivo, we compared the gene expression profiles of highly purified…”
Get full text

Nutritional Regulation of Intestinal Stem Cells by Alonso, Salvador, Yilmaz, Ömer H

“…Dietary composition and calorie intake are major determinants of health and disease. Calorie restriction promotes metabolic changes that favor tissue…”
Get full text

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma by Tammela, Tuomas, Sanchez-Rivera, Francisco J., Cetinbas, Naniye Malli, Wu, Katherine, Joshi, Nikhil S., Helenius, Katja, Park, Yoona, Azimi, Roxana, Kerper, Natanya R., Wesselhoeft, R. Alexander, Gu, Xin, Schmidt, Leah, Cornwall-Brady, Milton, Yilmaz, Ömer H., Xue, Wen, Katajisto, Pekka, Bhutkar, Arjun, Jacks, Tyler

“…A subset of Kras and p53 mutant cancer cells acts as a Wnt-producing niche for another cancer cell subset, and porcupine inhibition disrupts Wnt secretion in…”
Get full text

Loss-induced suppression and revival of lasing by Peng, B., Özdemir, Ş. K., Rotter, S., Yilmaz, H., Liertzer, M., Monifi, F., Bender, C. M., Nori, F., Yang, L.

“…Controlling and reversing the effects of loss are major challenges in optical systems. For lasers, losses need to be overcome by a sufficient amount of gain to…”
Get full text

Gut organoids: mini-tissues in culture to study intestinal physiology and disease by Almeqdadi, Mohammad, Mana, Miyeko D, Roper, Jatin, Yilmaz, Ömer H

“…In vitro, cell cultures are essential tools in the study of intestinal function and disease. For the past few decades, monolayer cellular cultures, such as…”
Get more information

Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer by Mihaylova, Maria M., Sabatini, David M., Yilmaz, Ömer H.

“…Organismal diet has a profound impact on tissue homeostasis and health in mammals. Adult stem cells are a keystone of tissue homeostasis that alters tissue…”
Get full text

Metabolism and Colorectal Cancer by Sedlak, Joseph C, Yilmaz, Ömer H, Roper, Jatin

“…Reprogrammed metabolism is a hallmark of colorectal cancer (CRC). CRC cells are geared toward rapid proliferation, requiring nutrients and the removal of…”
Get full text

Three-Dimensional Channel Characteristics for Molecular Communications With an Absorbing Receiver by Yilmaz, H. Birkan, Heren, Akif Cem, Tugcu, Tuna, Chan-Byoung Chae

“…Within the domain of molecular communications, researchers mimic the techniques in nature to come up with alternative communication methods for collaborating…”
Get full text

Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury by Goto, Norihiro, Goto, Saori, Imada, Shinya, Hosseini, Sahar, Deshpande, Vikram, Yilmaz, Ömer H.

“…Lgr5+ intestinal stem cells (ISCs) depend on niche factors for their proper function. However, the source of these ISC niche factors and how they support ISCs…”
Get full text

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake by Yilmaz, Ömer H., Katajisto, Pekka, Lamming, Dudley W., Gültekin, Yetis, Bauer-Rowe, Khristian E., Sengupta, Shomit, Birsoy, Kivanc, Dursun, Abdulmetin, Yilmaz, V. Onur, Selig, Martin, Nielsen, G. Petur, Mino-Kenudson, Mari, Zukerberg, Lawrence R., Bhan, Atul K., Deshpande, Vikram, Sabatini, David M.

“…How adult tissue stem and niche cells respond to the nutritional state of an organism is not well understood. Here we find that Paneth cells, a key constituent…”
Get full text

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer by Cheung, Priscilla, Xiol, Jordi, Dill, Michael T., Yuan, Wei-Chien, Panero, Riccardo, Roper, Jatin, Osorio, Fernando G., Maglic, Dejan, Li, Qi, Gurung, Basanta, Calogero, Raffaele A., Yilmaz, Ömer H., Mao, Junhao, Camargo, Fernando D.

“…Although the Hippo transcriptional coactivator YAP is considered oncogenic in many tissues, its roles in intestinal homeostasis and colorectal cancer (CRC)…”
Get full text

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors by Beyaz, Semir, Mana, Miyeko D., Roper, Jatin, Kedrin, Dmitriy, Saadatpour, Assieh, Hong, Sue-Jean, Bauer-Rowe, Khristian E., Xifaras, Michael E., Akkad, Adam, Arias, Erika, Pinello, Luca, Katz, Yarden, Shinagare, Shweta, Abu-Remaileh, Monther, Mihaylova, Maria M., Lamming, Dudley W., Dogum, Rizkullah, Guo, Guoji, Bell, George W., Selig, Martin, Nielsen, G. Petur, Gupta, Nitin, Ferrone, Cristina R., Deshpande, Vikram, Yuan, Guo-Cheng, Orkin, Stuart H., Sabatini, David M., Yilmaz, Ömer H.

“…Little is known about how pro-obesity diets regulate tissue stem and progenitor cell function. Here we show that high-fat diet (HFD)-induced obesity augments…”
Get full text

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity by Mana, Miyeko D., Hussey, Amanda M., Tzouanas, Constantine N., Imada, Shinya, Barrera Millan, Yesenia, Bahceci, Dorukhan, Saiz, Dominic R., Webb, Anna T., Lewis, Caroline A., Carmeliet, Peter, Mihaylova, Maria M., Shalek, Alex K., Yilmaz, Ömer H.

“…Obesity is an established risk factor for cancer in many tissues. In the mammalian intestine, a pro-obesity high-fat diet (HFD) promotes regeneration and…”
Get full text

Colonoscopy-based colorectal cancer modeling in mice with CRISPR–Cas9 genome editing and organoid transplantation by Roper, Jatin, Tammela, Tuomas, Akkad, Adam, Almeqdadi, Mohammad, Santos, Sebastian B, Jacks, Tyler, Yilmaz, Ömer H

“…Colonoscopy-guided mucosal injection is used to induce site-directed tumors and to transplant tumors into the distal colons of mice. Tumors for engraftment are…”
Get full text

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells by YILMAZ, Ömer H, VALDEZ, Riccardo, THEISEN, Brian K, WEI GUO, FERGUSON, David O, HONG WU, MORRISON, Sean J

“…Recent advances have highlighted extensive phenotypic and functional similarities between normal stem cells and cancer stem cells. This raises the question of…”
Get full text

Laravel design patterns and best practices: enhance the quality of your web applications by efficiently implementing design patterns in Laravel by Kılıçdağı, Arda, YILMAZ, H. İbrahim

“…This book covers how to develop different applications and solve recurring problems using Laravel 4 design patterns. It will walk you through the widely used…”
Get full text

Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging by Mihaylova, Maria M., Cheng, Chia-Wei, Cao, Amanda Q., Tripathi, Surya, Mana, Miyeko D., Bauer-Rowe, Khristian E., Abu-Remaileh, Monther, Clavain, Laura, Erdemir, Aysegul, Lewis, Caroline A., Freinkman, Elizaveta, Dickey, Audrey S., La Spada, Albert R., Huang, Yanmei, Bell, George W., Deshpande, Vikram, Carmeliet, Peter, Katajisto, Pekka, Sabatini, David M., Yilmaz, Ömer H.

“…Diet has a profound effect on tissue regeneration in diverse organisms, and low caloric states such as intermittent fasting have beneficial effects on…”
Get full text

Nutritional Control of Intestinal Stem Cells in Homeostasis and Tumorigenesis by Calibasi-Kocal, Gizem, Mashinchian, Omid, Basbinar, Yasemin, Ellidokuz, Ender, Cheng, Chia-Wei, Yilmaz, Ömer H.

“…Food and nutrition have a profound impact on organismal health and diseases, and tissue-specific adult stem cells play a crucial role in coordinating tissue…”
Get full text

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis by Jackstadt, Rene, van Hooff, Sander R., Leach, Joshua D., Cortes-Lavaud, Xabier, Lohuis, Jeroen O., Ridgway, Rachel A., Wouters, Valérie M., Roper, Jatin, Kendall, Timothy J., Roxburgh, Campbell S., Horgan, Paul G., Nixon, Colin, Nourse, Craig, Gunzer, Matthias, Clark, William, Hedley, Ann, Yilmaz, Omer H., Rashid, Mamunur, Bailey, Peter, Biankin, Andrew V., Campbell, Andrew D., Adams, David J., Barry, Simon T., Steele, Colin W., Medema, Jan Paul, Sansom, Owen J.

“…The metastatic process of colorectal cancer (CRC) is not fully understood and effective therapies are lacking. We show that activation of NOTCH1 signaling in…”
Get full text

MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer by Venkateswaran, Niranjan, Lafita-Navarro, M Carmen, Hao, Yi-Heng, Kilgore, Jessica A, Perez-Castro, Lizbeth, Braverman, Jonathan, Borenstein-Auerbach, Nofit, Kim, Min, Lesner, Nicholas P, Mishra, Prashant, Brabletz, Thomas, Shay, Jerry W, DeBerardinis, Ralph J, Williams, Noelle S, Yilmaz, Omer H, Conacci-Sorrell, Maralice

“…Tumors display increased uptake and processing of nutrients to fulfill the demands of rapidly proliferating cancer cells. Seminal studies have shown that the…”
Get full text