Search Results - "Yigit, Erbay"
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The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1
Published in PloS one (08-11-2023)“…The chemical modification of RNA bases represents a ubiquitous activity that spans all domains of life. Pseudouridylation is the most common RNA modification…”
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2
A method for selectively enriching microbial DNA from contaminating vertebrate host DNA
Published in PloS one (28-10-2013)“…DNA samples derived from vertebrate skin, bodily cavities and body fluids contain both host and microbial DNA; the latter often present as a minor component…”
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Expression of Human ACE2 N-terminal Domain, Part of the Receptor for SARS-CoV-2, in Fusion With Maltose-Binding Protein, E. coli Ribonuclease I and Human RNase A
Published in Frontiers in microbiology (11-06-2021)“…Graphical Abstract Cartoon illustration part of this work (Human ACE2 N-terminal domain tethered to RNase A and RNA degradation by the fusion enzyme). The…”
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4
An RIG-I-Like RNA helicase mediates antiviral RNAi downstream of viral siRNA biogenesis in Caenorhabditis elegans
Published in PLoS pathogens (01-02-2009)“…Dicer ribonucleases of plants and invertebrate animals including Caenorhabditis elegans recognize and process a viral RNA trigger into virus-derived small…”
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Genome and Metagenome Sequencing: Using the Human Methyl-Binding Domain to Partition Genomic DNA Derived from Plant Tissues
Published in Applications in plant sciences (01-11-2014)“…Premise of the study: Variation in the distribution of methylated CpG (methyl-CpG) in genomic DNA (gDNA) across the tree of life is biologically interesting…”
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A novel enrichment strategy reveals unprecedented number of novel transcription start sites at single base resolution in a model prokaryote and the gut microbiome
Published in BMC genomics (08-03-2016)“…The initiating nucleotide found at the 5' end of primary transcripts has a distinctive triphosphorylated end that distinguishes these transcripts from all…”
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Comparative analysis of strand-specific RNA sequencing approaches
Published in BMC proceedings (01-10-2012)“…Doc number: P30…”
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A fast solution to NGS library preparation with low nanogram DNA input
Published in BMC proceedings (01-10-2012)“…Doc number: P26…”
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The amino terminus of the coat protein of Turnip crinkle virus is the AVR factor recognized by resistant arabidopsis
Published in Molecular plant-microbe interactions (01-09-2000)“…We have isolated three naturally occurring strains of Turnip crinkle virus (TCV) that break resistance in Di-17 Arabidopsis. Two mutations in the N terminus of…”
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10
Human RNase 4 improves mRNA sequence characterization by LC–MS/MS
Published in Nucleic acids research (14-10-2022)“…Abstract With the rapid growth of synthetic messenger RNA (mRNA)-based therapeutics and vaccines, the development of analytical tools for characterization of…”
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E. coli RNase I exhibits a strong Ca2+-dependent inherent double-stranded RNase activity
Published in Nucleic acids research (21-05-2021)“…Abstract Since its initial characterization, Escherichia coli RNase I has been described as a single-strand specific RNA endonuclease that cleaves its…”
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Discovery of cytosine deaminases enables base-resolution methylome mapping using a single enzyme
Published in Molecular cell (07-03-2024)“…Deaminases have important uses in modification detection and genome editing. However, the range of applications is limited by the small number of characterized…”
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13
Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi
Published in Cell (17-11-2006)“…Argonaute (AGO) proteins interact with small RNAs to mediate gene silencing. C. elegans contains 27 AGO genes, raising the question of what roles these genes…”
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The dsRNA Binding Protein RDE-4 Interacts with RDE-1, DCR-1, and a DExH-Box Helicase to Direct RNAi in C. elegans
Published in Cell (28-06-2002)“…Double-stranded (ds) RNA induces potent gene silencing, termed RNA interference (RNAi). At an early step in RNAi, an RNaseIII-related enzyme, Dicer (DCR-1),…”
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Enhanced expression and purification of nucleotide-specific ribonucleases MC1 and Cusativin
Published in Protein expression and purification (01-02-2022)“…Combinations of ribonucleases (RNases) are commonly used to digest RNA into oligoribonucleotide fragments prior to liquid chromatography-mass spectrometry…”
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The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1
Published in PloS one (01-01-2023)Get full text
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Abstract 820: Enzymatic Methyl-Seq: methylome analysis of challenging DNA samples
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract DNA isolated from blood draws (cell-free DNA (cfDNA)) or from archival material like formalin fixed paraffin embedded (FFPE) tissues have advanced the…”
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High-resolution nucleosome mapping of targeted regions using BAC-based enrichment
Published in Nucleic acids research (01-04-2013)“…We report a target enrichment method to map nucleosomes of large genomes at unprecedented coverage and resolution by deeply sequencing locus-specific…”
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Abstract 5406: Low-input transcript profiling with enhanced sensitivity using a highly efficient, low-bias and strand-specific RNA-Seq library preparation method
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract RNA-seq has become the most popular method for transcriptome analysis and is widely used to study gene expression, detect mutations, fusion…”
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High-density nucleosome occupancy map of human chromosome 9p21-22 reveals chromatin organization of the type I interferon gene cluster
Published in Journal of interferon & cytokine research (01-09-2014)“…Genome-wide investigations have dramatically increased our understanding of nucleosome positioning and the role of chromatin in gene regulation, yet some…”
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