Search Results - "Yi-Fang Wu"
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URB597 protects against NLRP3 inflammasome activation by inhibiting autophagy dysfunction in a rat model of chronic cerebral hypoperfusion
Published in Journal of neuroinflammation (09-12-2019)“…Previous studies reported that URB597 (URB) had therapeutic potential for treating chronic cerebral hypoperfusion (CCH)-induced neuroinflammation and autophagy…”
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Synthesis, Self-Assembly, and Cell Responses of Aromatic IKVAV Peptide Amphiphiles
Published in Molecules (Basel, Switzerland) (27-06-2022)“…Synthetic bioactive aromatic peptide amphiphiles have been recognized as key elements of emerging biomedical strategies due to their biocompatibility, design…”
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Fecal microbiota transplantation and short‐chain fatty acids protected against cognitive dysfunction in a rat model of chronic cerebral hypoperfusion
Published in CNS neuroscience & therapeutics (01-06-2023)“…Aims Clear roles and mechanisms in explaining gut microbial dysbiosis and microbial metabolites short‐chain fatty acids (SCFAs) alterations in chronic cerebral…”
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Fecal microbiota transplantation and replenishment of short-chain fatty acids protect against chronic cerebral hypoperfusion-induced colonic dysfunction by regulating gut microbiota, differentiation of Th17 cells, and mitochondrial energy metabolism
Published in Journal of neuroinflammation (26-12-2022)“…Little is known about the association between gut microbiota and intestinal injury under a state of chronic cerebral hypoperfusion (CCH). Here, the effects of…”
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Inhibition of excessive autophagy and mitophagy mediates neuroprotective effects of URB597 against chronic cerebral hypoperfusion
Published in Cell death & disease (28-06-2018)“…URB597 (URB) has therapeutic potential for treating chronic cerebral hypoperfusion (CCH)-induced neuronal death. The present study investigated the protective…”
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Association of vaccine‐specific regulatory T cells with reduced antibody response to repeated influenza vaccination
Published in European journal of immunology (01-12-2023)“…Repeated annual influenza vaccinations have been associated with reduced vaccine‐induced antibody responses. This prospective study aimed to explore the role…”
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The aromatic fullerene-like silicon cage with 12 Si5 pentagons stabilized by a V3 unit
Published in Theoretical chemistry accounts (01-07-2020)“…Silicon clusters doped with transition-metal (TM) atoms not only can hold stable fullerene-like structures, but also can exhibit unique electronic properties…”
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Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-10-2019)“…Andrographolide is a medical herbal compound with documented anti-inflammatory activity and therapeutic efficacy in animal models of Alzheimer’s disease,…”
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The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo
Published in Molecular therapy. Nucleic acids (01-08-2014)“…Persistence of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) under current antiviral therapy is a major barrier to eradication of chronic…”
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The effect of pay-for-performance program on infection events and mortality rate in diabetic patients: a nationwide population-based cohort study
Published in BMC health services research (21-01-2021)“…Diabetes mellitus is a known risk factor for infection. Pay for Performance (P4P) program is designed to enhance the comprehensive patient care. The aim of…”
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Permanent Inactivation of HBV Genomes by CRISPR/Cas9-Mediated Non-cleavage Base Editing
Published in Molecular therapy. Nucleic acids (05-06-2020)“…Current antiviral therapy fails to cure chronic hepatitis B virus (HBV) infection because of persistent covalently closed circular DNA (cccDNA)…”
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Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 ameliorate neuroinflammatory responses in chronic cerebral hypoperfusion model by blocking NF-κB pathways
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-12-2017)“…The present study explored the protective effects of cannabinoid receptor agonist WIN55,212-2 (WIN) and fatty acid amide hydrolase inhibitor URB597 (URB)…”
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Cannabinoid receptor agonist WIN55,212-2 and fatty acid amide hydrolase inhibitor URB597 may protect against cognitive impairment in rats of chronic cerebral hypoperfusion via PI3K/AKT signaling
Published in Behavioural brain research (15-10-2016)“…•WIN55,212-2 and URB597 protect neurons against cognitive impairment.•WIN55,212-2 and URB597 inhibited cognitive impairment via the PI3K/AKT…”
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Effect of Molecular Chain Length on the Mechanical and Thermal Properties of Amine-Functionalized Graphene Oxide/Polyimide Composite Films Prepared by In Situ Polymerization
Published in ACS applied materials & interfaces (13-02-2013)“…This study fabricates amine (NH2)-functionalized graphene oxide (GO)/polyimide(PI) composite films with high performance using in situ polymerization. Linear…”
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Modification of geometrical and electronic structures of anionic and neutral silicon clusters by double-doped tantalum atoms
Published in Molecular physics (01-12-2020)“…In this work, structural evolution, geometrical and electronic structures of Ta 2 Si n − and Ta 2 Si n (n = 3-21) clusters are investigated by joint Crystal…”
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Vaccine-induced antigen-specific regulatory T cells attenuate the antiviral immunity against acute influenza virus infection
Published in Mucosal immunology (01-07-2018)“…Peptide-based T cell vaccines targeting the conserved epitopes of influenza virus can provide cross-protection against distantly related strains, but they are…”
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Asthma medication increases dental caries among children in Taiwan: An analysis using the National Health Insurance Research Database
Published in Journal of dental sciences (01-12-2019)“…Asthma is a common, chronic disease that causes respiratory symptoms in children. Dental caries is also a common chronic disease in the pediatric population…”
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The effects of intracranial pressure monitoring in patients with traumatic brain injury
Published in PloS one (21-02-2014)“…Although international guideline recommended routine intracranial pressure (ICP) monitoring for patients with severe traumatic brain injury(TBI), there were…”
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Comorbidity in Older Patients Hospitalized with Cancer in Northeast China based on Hospital Discharge Data
Published in International journal of environmental research and public health (31-10-2020)“…Patients with cancer often carry the dual burden of the cancer itself and other co-existing medical conditions. The problems associated with comorbidities…”
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