Search Results - "Yi, Sang Ah"

Anti-adipogenic Pregnane Steroid from a Hydractinia-associated Fungus, Cladosporium sphaerospermum SW67 by Lee, Seoung-Rak, Kang, Heesun, Yoo, Min-Jeong, Yi, Sang-Ah, Christine, Beemelmanns, Lee, Jaecheol, Kim, Ki Hyun

“…A pregnane steroid, 3α-hydroxy-pregn-7-ene-6,20-dione (1), was isolated from a Hydractinia-associated Cladosporium sphaerospermum SW67 by repetitive column…”
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Bioengineering Approaches for the Advanced Organoid Research by Yi, Sang Ah, Zhang, Yixiao, Rathnam, Christopher, Pongkulapa, Thanapat, Lee, Ki‐Bum

“…Recent advances in 3D cell culture technology have enabled scientists to generate stem cell derived organoids that recapitulate the structural and functional…”
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Identification of anti-adipogenic withanolides from the roots of Indian ginseng (Withania somnifera) by Lee, Seoung Rak, Lee, Bum Soo, Yu, Jae Sik, Kang, Heesun, Yoo, Min Jeong, Yi, Sang Ah, Han, Jeung-Whan, Kim, Sil, Kim, Jung Kyu, Kim, Jin-Chul, Kim, Ki Hyun

“…Background: Withania somnifera (Solanaceae), generally known as Indian ginseng, is a medicinal plant that is used in Ayurvedic practice for promoting health…”
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Epigenetic role of nuclear S6K1 in early adipogenesis by Yi, Sang Ah, Han, Jihoon, Han, Jeung-Whan

“…S6K1 is a key regulator of cell growth, cell size, and metabolism. Although the role of cytosolic S6K1 in cellular processes is well established, the function…”
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Anti-adipogenic Pregnane Steroid from a Hydractinia-associated Fungus, Cladosporium sphaerospermum SW67 by Lee, Seoung Rak, Kang, Heesun, Yoo, Min Jeong, Yu, Jae Sik, Lee, Seulah, Yi, Sang Ah, Beemelmanns, Christine, Lee, Jaecheol, Kim, Ki Hyun

“…A pregnane steroid, 3α-hydroxy-pregn-7-ene-6,20-dione (1), was isolated from a Hydractinia-associated Cladosporium sphaerospermum SW67 by repetitive column…”
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Fermented ginseng extract, BST204, disturbs adipogenesis of mesenchymal stem cells through inhibition of S6 kinase 1 signaling by Yi, Sang Ah, Lee, Jieun, Park, Sun Kyu, Kim, Jeom Yong, Park, Jong Woo, Lee, Min Gyu, Nam, Ki Hong, Park, Jee Hun, Oh, Hwamok, Kim, Saetbyul, Han, Jihoon, Kim, Bo Kyung, Jo, Dong-Gyu, Han, Jeung-Whan

“…Background: The biological and pharmacological effects of BST204, a fermented ginseng extract, have been reported in various disease conditions. However, its…”
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Infection of Brain Organoids and 2D Cortical Neurons with SARS-CoV-2 Pseudovirus by Yi, Sang Ah, Nam, Ki Hong, Yun, Jihye, Gim, Dongmin, Joe, Daeho, Kim, Yong Ho, Kim, Han-Joo, Han, Jeung-Whan, Lee, Jaecheol

“…Since the global outbreak of SARS-CoV-2 (COVID-19), infections of diverse human organs along with multiple symptoms continue to be reported. However, the…”
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Developing MiR‐133a Zipper Nanoparticles for Targeted Enhancement of Thermogenic Adipocyte Generation by Yi, Sang Ah, Pongkulapa, Thanapat, Nevins, Sarah, Goldston, Li Ling, Chen, Meizi, Lee, Ki‐Bum

“…Existing delivery methods for RNAi therapeutics encounter challenges, including stability, specificity, and off‐target effects, which restrict their clinical…”
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Ginsenoside Rg3 Induces Browning of 3T3-L1 Adipocytes by Activating AMPK Signaling by Kim, Kyungtae, Nam, Ki Hong, Yi, Sang Ah, Park, Jong Woo, Han, Jeung-Whan, Lee, Jaecheol

“…Ginsenoside Rg3, one of the major components in , has been reported to possess several therapeutic effects including anti-obesity properties. However, its…”
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Rg3 and Rh2 ginsenosides suppress embryoid body formation by inhibiting the epithelial-mesenchymal transition by Noh, Jae Sung, Jeong, Jae Kyun, Han, Jeung-Whan, Yi, Sang Ah

“…Numerous active compounds derived from ginseng exhibit various pharmacological and therapeutic effects in humans. Despite the benefits of ginsenosides, little…”
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S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis by Yi, Sang Ah, Um, Sung Hee, Lee, Jaecheol, Yoo, Ji Hee, Bang, So Young, Park, Eun Kyung, Lee, Min Gyu, Nam, Ki Hong, Jeon, Ye Ji, Park, Jong Woo, You, Jueng Soo, Lee, Sang-Jin, Bae, Gyu-Un, Rhie, Jong Won, Kozma, Sara C., Thomas, George, Han, Jeung-Whan

“…S6K1 has been implicated in a number of key metabolic responses, which contribute to obesity. Critical among these is the control of a transcriptional program…”
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HP1γ Sensitizes Cervical Cancer Cells to Cisplatin through the Suppression of UBE2L3 by Yi, Sang Ah, Kim, Go Woon, Yoo, Jung, Han, Jeung-Whan, Kwon, So Hee

“…Cisplatin is the most frequently used agent for chemotherapy against cervical cancer. However, recurrent use of cisplatin induces resistance, representing a…”
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In vitro modeling for inherited neurological diseases using induced pluripotent stem cells: from 2D to organoid by Nam, Ki Hong, Yi, Sang Ah, Jang, Hyun Ji, Han, Jeung-Whan, Lee, Jaecheol

“…Stem cells are characterized by self-renewal and by their ability to differentiate into cells of various organs. With massive progress in 2D and 3D cell…”
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Identification of anti-adipogenic withanolides from the roots of Indian ginseng (Withania somnifera) by Lee, Seoung Rak, Lee, Bum Soo, Yu, Jae Sik, Kang, Heesun, Yoo, Min Jeong, Yi, Sang Ah, Han, Jeung-Whan, Kim, Sil, Kim, Jung Kyu, Kim, Jin-Chul, Kim, Ki Hyun

“…Withania somnifera (Solanaceae), generally known as Indian ginseng, is a medicinal plant that is used in Ayurvedic practice for promoting health and longevity…”
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Heterochromatin Protein 1: A Multiplayer in Cancer Progression by Jeon, Yu Hyun, Kim, Go Woon, Kim, So Yeon, Yi, Sang Ah, Yoo, Jung, Kim, Ji Yoon, Lee, Sang Wu, Kwon, So Hee

“…Dysregulation of epigenetic mechanisms as well as genomic mutations contribute to the initiation and progression of cancer. In addition to histone code…”
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Reversine promotes browning of white adipocytes by suppressing miR‐133a by Kim, Saetbyul, Park, Jong Woo, Lee, Min Gyu, Nam, Ki Hong, Park, Jee Hun, Oh, Hwamok, Lee, Jieun, Han, Jihoon, Yi, Sang Ah, Han, Jeung‐Whan

“…Brown adipocytes are characterized by a high number of uncoupling protein 1 (UCP1)‐positive mitochondrial content and increased thermogenic capacity. As…”
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Identification of a novel S6K1 inhibitor, rosmarinic acid methyl ester, for treating cisplatin-resistant cervical cancer by Nam, Ki Hong, Yi, Sang Ah, Nam, Gibeom, Noh, Jae Sung, Park, Jong Woo, Lee, Min Gyu, Park, Jee Hun, Oh, Hwamok, Lee, Jieun, Lee, Kang Ro, Park, Hyun-Ju, Lee, Jaecheol, Han, Jeung-Whan

“…The mTOR/S6K1 signaling pathway is often activated in cervical cancer, and thus considered a molecular target for cervical cancer therapies. Inhibiting mTOR is…”
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S6K1 controls adiponectin expression by inducing a transcriptional switch: BMAL1-to-EZH2 by Yi, Sang Ah, Jeon, Ye Ji, Lee, Min Gyu, Nam, Ki Hong, Ann, Sora, Lee, Jaecheol, Han, Jeung-Whan

“…Adiponectin (encoded by Adipoq ), a fat-derived hormone, alleviates risk factors associated with metabolic disorders. Although many transcription factors are…”
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Rosmarinic Acid Methyl Ester Regulates Ovarian Cancer Cell Migration and Reverses Cisplatin Resistance by Inhibiting the Expression of Forkhead Box M1 by Lim, Soo Hyun, Nam, Ki Hong, Kim, Kyungtae, Yi, Sang Ah, Lee, Jaecheol, Han, Jeung-Whan

“…Rosmarinic acid methyl ester (RAME), a derivative of rosmarinic acid (RA), is reported to have several therapeutic effects, including anti-tumor effects…”
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Transcriptomics-Based Repositioning of Natural Compound, Eudesmin, as a PRC2 Modulator by Yi, Sang Ah, Nam, Ki Hong, Lee, Min Gyu, Oh, Hwamok, Noh, Jae Sung, Jeong, Jae Kyun, Kwak, Sangwoo, Jeon, Ye Ji, Kwon, So Hee, Lee, Jaecheol, Han, Jeung-Whan

“…Extensive epigenetic remodeling occurs during the cell fate determination of stem cells. Previously, we discovered that eudesmin regulates lineage commitment…”
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