Evaluation of the Xpert Xpress GBS test for rapid detection of group B Streptococcus in pregnant women

Evaluation of the Xpert Xpress GBS test for rapid detection of group B Streptococcus in pregnant women

This was the first study evaluating the performance of the Xpert Xpress group B (GBS) test using rectovaginal swabs from Chinese pregnant women. Compared to the other three assays, the Xpert Xpress GBS test demonstrated high sensitivity and specificity when screening 939 pregnant women for GBS in re...

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Bibliographic Details
Published in:Microbiology spectrum Vol. 12; no. 1; p. e0220623
Main Authors: Wang, Feiling, Yi, Lehui, Ming, Fang, Dong, Rui, Wang, Feng, Chen, Ruirui, Hu, Xiaoling, Chen, Xuri, Sun, Bo, Tang, Yi-Wei, Zhu, Yuanfang, Wu, Lijuan
Format: Journal Article
Language:English
Published: United States American Society for Microbiology 11-01-2024
Subjects:
Clinical Microbiology
direct culture
enrichment culture
Female
group B Streptococcus
Humans
Pregnancy
Pregnancy Complications, Infectious - diagnosis
Pregnant Women
qPCR
Research Article
Streptococcal Infections - diagnosis
Streptococcus agalactiae - genetics
Vagina
Xpert Xpress GBS
group B Streptococcus
Xpert Xpress GBS
direct culture
enrichment culture
qPCR
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Summary:This was the first study evaluating the performance of the Xpert Xpress group B (GBS) test using rectovaginal swabs from Chinese pregnant women. Compared to the other three assays, the Xpert Xpress GBS test demonstrated high sensitivity and specificity when screening 939 pregnant women for GBS in rectovaginal specimens. Additionally, its reduced time to obtain results makes it valuable for the rapid detection of GBS.
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Feiling Wang and Lehui Yi contributed equally to this article. The order of authors was determined by the corresponding author after negotiation.
X.H. and Y.W.T. are employees of Cepheid, the commercial manufacturer of the Xpert Xpress GBS test. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
ISSN:2165-0497
2165-0497
DOI:10.1128/spectrum.02206-23