Search Results - "Yi, Jingyan"

Hormonal influence: unraveling the impact of sex hormones on vascular smooth muscle cells by Jia, Keran, Luo, Xin, Yi, Jingyan, Zhang, Chunxiang

“…Sex hormones play a pivotal role as endocrine hormones that exert profound effects on the biological characteristics and vascular function of vascular smooth…”
Get full text

Integrated bioinformatics analysis and screening of hub genes in polycystic ovary syndrome by Qiao, Gan, Xing, Jinshan, Luo, Xin, Zhang, Chunxiang, Yi, Jingyan

“…Purpose Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic disorders, posing a serious threat to the health of women. Herein,…”
Get full text

Comprehensive analysis of LASS6 expression and prognostic value in ovarian cancer by Xing, Jinshan, Yi, Jingyan

“…Ceramide plays an important role in the occurrence and development of tumor. The synthesis of ceramide needs the participation of LASS. Current studies have…”
Get full text

The utilization of nanotechnology in the female reproductive system and related disorders by Luo, Xin, Jia, Keran, Xing, Jinshan, Yi, Jingyan

“…The health of the reproductive system is intricately linked to female fertility and quality of life. There has been a growing prevalence of reproductive system…”
Get full text

BTF3 confers oncogenic activity in prostate cancer through transcriptional upregulation of Replication Factor C by Zhang, Yuan, Gao, Xiang, Yi, Jingyan, Sang, Xiaolin, Dai, Zhihong, Tao, Zhiwei, Wang, Min, Shen, Lanlin, Jia, Yaxun, Xie, Daqing, Cheng, Hailing, Liu, Zhiyu, Liu, Pixu

“…High levels of Basic Transcription Factor 3 (BTF3) have been associated with prostate cancer. However, the mechanisms underlying the role of BTF3 as an…”
Get full text

Micelle encapsulation zinc‐doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair by Yi, Jingyan, Luo, Xin, Xing, Jinshan, Gedanken, Aharon, Lin, Xiukun, Zhang, Chunxiang, Qiao, Gan

“…Micelle Encapsulation Zinc‐doped copper oxide nanocomposites (MEnZn‐CuO NPs) is a novel doped metal nanomaterial prepared by our group based on Zinc doped…”
Get full text

Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome by Xing, Jinshan, Luo, Xin, Jia, Keran, Liu, Shuang, Chen, Shaokun, Qiao, Gan, Zhang, Chunxiang, Yi, Jingyan

“…Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder in women of reproductive age that still lacks effective treatment. Inflammation is…”
Get full text

Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer by Wang, Min, Xue, Yijue, Shen, Lanlin, Qin, Pan, Sang, Xiaolin, Tao, Zhiwei, Yi, Jingyan, Wang, Jia, Liu, Pixu, Cheng, Hailing

“…Cervical cancer has poor prognosis and patients are often diagnosed at advanced stages of the disease with limited treatment options. There is thus an urgent…”
Get full text

The c.323 G>C mutation in LORICRIN causes new-found late-onset autosomal dominant loricrin keratoderma in a Chinese Han Pedigree by Gao, Xiaojie, Li, Hua, Zhao, Songhua, Li, Xiabin, Zhao, Jiao, Long, Yang, Zhang, Jun, Liao, Yongmei, Li, Shengbiao, Guo, Kai, Yi, Jingyan, Chen, Shaokun, Ma, Mingyi

“…Loricrin keratoderma is a rare early-onset autosomal dominant skin disorder. At present, no clinical reports have been published on characteristics of…”
Get full text

Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome by Xing, Jinshan, Qiao, Gan, Luo, Xin, Liu, Shuang, Chen, Shaokun, Ye, Geng, Zhang, Chunxiang, Yi, Jingyan

“…Polycystic ovary syndrome (PCOS), a common reproductive endocrine disorder in women of reproductive age, causes anovulatory infertility. Increased apoptosis of…”
Get more information

Research update on the anticancer effects of buparlisib by Xing, Jinshan, Yang, Jun, Gu, Yingjiang, Yi, Jingyan

“…Buparlisib is a highly efficient and selective PI3K inhibitor and a member of the 2,6-dimorpholinopyrimidine-derived family of compounds. It selectively…”
Get full text

Targeting the EphB4 receptor tyrosine kinase sensitizes HER2-positive breast cancer cells to Lapatinib by Ding, Jinlei, Yao, Yating, Huang, Gena, Wang, Xiaonan, Yi, Jingyan, Zhang, Nan, Liu, Chongya, Wang, Kainan, Zhang, Yuan, Wang, Min, Liu, Pixu, Ye, Mingliang, Li, Man, Cheng, Hailing

“…Clinical data analysis reveals that the expression of the EphB4 receptor tyrosine kinase is significantly elevated in HER2-positive breast cancer and high…”
Get full text

Network Pharmacology Analysis and Experimental Pharmacology Study Explore the Mechanism of Asparagus against Glioblastoma by Luo, Xin, Xing, Jinshan, Gu, Yingjiang, Qiao, Gan, Liu, Minghua, Yi, Jingyan

“…Glioblastoma (GBM) is the most malignant primary brain tumor, and there is an urgent need to explore effective therapeutic strategies to improve the prognosis…”
Get full text

Inhibition of BTF3 sensitizes luminal breast cancer cells to PI3Kα inhibition through the transcriptional regulation of ERα by Ding, Jinlei, Wang, Xiaonan, Zhang, Yuan, Sang, Xiaolin, Yi, Jingyan, Liu, Chongya, Liu, Zundong, Wang, Min, Zhang, Nan, Xue, Yijue, Shen, Lanlin, Zhao, Wenzhi, Luo, Fuwen, Liu, Pixu, Cheng, Hailing

“…Selective phosphatidylinositol 3 kinase (PI3K) inhibitors are being actively tested in clinical trials for ERα-positive (ER+) breast cancer due to the presence…”
Get full text

MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer by Yi, Jingyan, Liu, Chongya, Tao, Zhiwei, Wang, Min, Jia, Yaxun, Sang, Xiaolin, Shen, Lanlin, Xue, Yijue, Jiang, Kui, Luo, Fuwen, Liu, Pixu, Cheng, Hailing

“…While PARP inhibitors and CDK4/6 inhibitors, the two classes of FDA-approved agents, have shown promising clinical benefits, there is an urgent need to develop…”
Get full text

Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation by Xiao, Zhen, He, Yingying, Liu, Chongya, Xiang, Lin, Yi, Jingyan, Wang, Min, Shen, Tingting, Shen, Lanlin, Xue, Yijue, Shi, Hong, Liu, Pixu

“…Uterine serous carcinoma (USC) is a subtype of endometrial cancer. Compared with endometrial endometroid carcinoma, the majority of USC cases are more…”
Get full text

MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancerResearch in context by Jingyan Yi, Chongya Liu, Zhiwei Tao, Min Wang, Yaxun Jia, Xiaolin Sang, Lanlin Shen, Yijue Xue, Kui Jiang, Fuwen Luo, Pixu Liu, Hailing Cheng

“…Background: While PARP inhibitors and CDK4/6 inhibitors, the two classes of FDA-approved agents, have shown promising clinical benefits, there is an urgent…”
Get full text