Search Results - "Yi, Hyojeong"

A Two-Component-System-Governed Regulon That Includes a β-Lactamase Gene is Responsive to Cell Envelope Disturbance by Lee, Dongju, Park, Jongwook, Yi, Hyojeong, Cho, Kwang-Hwi, Kim, Heenam Stanley

“…β-Lactamase production facilitates bacterial survival in nature and affects many infection therapies. However, much of its regulation remains unexplored. We…”
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SreA-mediated iron regulation in Aspergillus fumigatus by Schrettl, Markus, Kim, H. Stanley, Eisendle, Martin, Kragl, Claudia, Nierman, William C, Heinekamp, Thorsten, Werner, Ernst R, Jacobsen, Ilse, Illmer, Paul, Yi, Hyojeong, Brakhage, Axel A, Haas, Hubertus

“…Aspergillus fumigatus, the most common airborne fungal pathogen of humans, employs two high-affinity iron uptake systems: iron uptake mediated by the…”
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The early stage of bacterial genome-reductive evolution in the host by Song, Han, Hwang, Junghyun, Yi, Hyojeong, Ulrich, Ricky L, Yu, Yan, Nierman, William C, Kim, Heenam Stanley

“…The equine-associated obligate pathogen Burkholderia mallei was developed by reductive evolution involving a substantial portion of the genome from…”
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Twelve positions in a β-lactamase that can expand its substrate spectrum with a single amino acid substitution by Yi, Hyojeong, Cho, Kwang-Hwi, Cho, Yun Sung, Kim, Karan, Nierman, William C, Kim, Heenam Stanley

“…The continuous evolution of β-lactamases resulting in bacterial resistance to β-lactam antibiotics is a major concern in public health, and yet the underlying…”
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The tandem repeats enabling reversible switching between the two phases of β-lactamase substrate spectrum by Yi, Hyojeong, Song, Han, Hwang, Junghyun, Kim, Karan, Nierman, William C, Kim, Heenam Stanley

“…Expansion or shrinkage of existing tandem repeats (TRs) associated with various biological processes has been actively studied in both prokaryotic and…”
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Substrate Spectrum Extension of PenA in Burkholderia thailandensis with a Single Amino Acid Deletion, Glu168del by YI, Hyojeong, KIM, Karan, CHO, Kwang-Hwi, JUNG, Oksung, HEENAM STANLEY KIM

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Non-catalytic-Region Mutations Conferring Transition of Class A β-Lactamases Into ESBLs by Cao, Thinh-Phat, Yi, Hyojeong, Dhanasingh, Immanuel, Ghosh, Suparna, Choi, Jin Myung, Lee, Kun Ho, Ryu, Seol, Kim, Heenam Stanley, Lee, Sung Haeng

“…Despite class A ESBLs carrying substitutions outside catalytic regions, such as Cys69Tyr or Asn136Asp, have emerged as new clinical threats, the molecular…”
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Opine-Based Agrobacterium Competitiveness: Dual Expression Control of the Agrocinopine Catabolism (acc) Operon by Agrocinopines and Phosphate Levels by KIM, H. Stanley, YI, Hyojeong, MYUNG, Jaehee, PIPER, Kevin R, FARRAND, Stephen K

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Antibiotic Scars Left on the Gut Microbiota from the Stringent Response by Yi, Hyojeong, Kim, Heenam Stanley

“…Current research is primarily focused on compositional shifts and alterations in the metabolic status of the gut microbiota to elucidate the damage caused by…”
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Bacterial persistence to antibiotics activated by tRNA mutations by Park, Jongwook, Lee, Dongju, Yi, Hyojeong, Yun, Cheol-Won, Kim, Heenam Stanley

“…Bacterial persistence is a significant cause of the intractability of chronic and relapsing infections. Despite its importance, many of the underlying…”
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Simple sequence repeat (SSR)-based gene diversity in Burkholderia pseudomallei and Burkholderia mallei by Song, Han, Hwang, Junghyun, Myung, Jaehee, Seo, Hyoseok, Yi, Hyojeong, Sim, Hee-Sun, Kim, Bong-Su, Nierman, William C, Kim, Heenam Stanley

“…Pathogens Burkholderia pseudomallei (Bp) and Burkholderia mallei (Bm) contain a large number (> 12,000) of Simple Sequence Repeats (SSRs). To study the extent…”
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Mutations in ArgS Arginine-tRNA Synthetase Confer Additional Antibiotic Tolerance Protection to Extended-Spectrum-β-Lactamase-Producing Burkholderia thailandensis by Yi, Hyojeong, Park, Jongwook, Cho, Kwang-Hwi, Kim, Heenam Stanley

“…Highly conserved PenI-type class A β-lactamase in pathogenic members of species can evolve to extended-spectrum β-lactamase (ESBL), which exhibits hydrolytic…”
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Mutations in MetG (methionyl-tRNA synthetase) and TrmD [tRNA (guanine-N1)-methyltransferase] conferring meropenem tolerance in Burkholderia thailandensis by Yi, Hyojeong, Lee, Hyeri, Cho, Kwang-Hwi, Kim, Heenam Stanley

“…Although meropenem is widely used to treat Burkholderia infections, the response of Burkholderia pathogens to this antibiotic is largely unexplored…”
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Engineering ligand-specific biosensors for aromatic amino acids and neurochemicals by Rottinghaus, Austin G, Xi, Chenggang, Amrofell, Matthew B, Yi, Hyojeong, Moon, Tae Seok

“…Microbial biosensors have diverse applications in metabolic engineering and medicine. Specific and accurate quantification of chemical concentrations allows…”
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Deletion mutations conferring substrate spectrum extension in the class A β-lactamase by Hwang, Junghyun, Cho, Kwang-Hwi, Song, Han, Yi, Hyojeong, Kim, Heenam Stanley

“…We describe four new deletion mutations in a class A β-lactamase PenA in Burkholderia thailandensis, each conferring an extended substrate spectrum…”
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High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A β-lactamase, PenL by Yi, Hyojeong, Choi, Jin Myung, Hwang, Junghyun, Prati, Fabio, Cao, Thinh-Phat, Lee, Sung Haeng, Kim, Heenam Stanley

“…The omega loop in β-lactamases plays a pivotal role in substrate recognition and catalysis, and some mutations in this loop affect the adaptability of the…”
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The Tandem Repeats Enabling Reversible Switching between the Two Phases of [beta]-Lactamase Substrate Spectrum: e1004640 by Yi, Hyojeong, Song, Han, Hwang, Junghyun, Kim, Karan, Nierman, William C, Kim, Heenam Stanley

“…Expansion or shrinkage of existing tandem repeats (TRs) associated with various biological processes has been actively studied in both prokaryotic and…”
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Twelve Positions in a [beta]-Lactamase That Can Expand Its Substrate Spectrum with a Single Amino Acid Substitution by Yi, Hyojeong, Cho, Kwang-Hwi, Cho, Yun Sung, Kim, Karan, Nierman, William C, Kim, Heenam Stanley

“…The continuous evolution of [beta]-lactamases resulting in bacterial resistance to [beta]-lactam antibiotics is a major concern in public health, and yet the…”
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High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A [beta]-lactamase, PenL by Yi, Hyojeong, Choi, Jin Myung, Hwang, Junghyun, Prati, Fabio, Cao, Thinh-phat, Lee, Sung Haeng, Kim, Heenam Stanley

“…The omega loop in β-lactamases plays a pivotal role in substrate recognition and catalysis, and some mutations in this loop affect the adaptability of the…”
Get full text

The Early Stage of Bacterial Genome-Reductive Evolution in the Host: e1000922 by Song, Han, Hwang, Junghyun, Yi, Hyojeong, Ulrich, Ricky L, Yu, Yan, Nierman, William C, Kim, Heenam Stanley

“…The equine-associated obligate pathogen Burkholderia mallei was developed by reductive evolution involving a substantial portion of the genome from…”
Get full text