Search Results - "Yi, Hwalin"
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CRISPR-based editing strategies to rectify EYA1 complex genomic rearrangement linked to haploinsufficiency
Published in Molecular therapy. Nucleic acids (11-06-2024)“…Pathogenic structure variations (SVs) are associated with various types of cancer and rare genetic diseases. Recent studies have used Cas9 nuclease with paired…”
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Journal Article -
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Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor
Published in Nucleic acids research (10-06-2024)“…Nucleotide repeat expansion disorders, a group of genetic diseases characterized by the expansion of specific DNA sequences, pose significant challenges to…”
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Journal Article