Search Results - "Yexing, Xian"
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Oxidative stress and inflammatory markers in ovarian follicular fluid of women with diminished ovarian reserve during in vitro fertilization
Published in Journal of ovarian research (23-10-2023)“…Background Follicular microenvironment has been proposed as an important factor for oocyte grown and maturation. We sought to evaluate the oxidative stress and…”
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The safety and effectiveness of genetically corrected iPSCs derived from β-thalassaemia patients in nonmyeloablative β-thalassaemic mice
Published in Stem cell research & therapy (16-07-2020)“…Background β-Thalassaemia is a clinically common cause of hereditary haemolytic anaemia stemming from mutations in important functional regions of the β-globin…”
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Autophagy Promoted the Degradation of Mutant ATXN3 in Neurally Differentiated Spinocerebellar Ataxia-3 Human Induced Pluripotent Stem Cells
Published in BioMed research international (01-01-2016)“…Spinocerebellar ataxia-3 (SCA3) is the most common dominant inherited ataxia worldwide and is caused by an unstable CAG trinucleotide expansion mutation within…”
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Noninvasive prenatal diagnosis of β‐thalassemia by relative haplotype dosage without analyzing proband
Published in Molecular genetics & genomic medicine (01-11-2019)“…Background β‐thalassemia is one of the most common monogenic diseases in the world. Southeast China is a highly infected area affected by four β‐thalassemia…”
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Generation of integration-free induced pluripotent stem cells (GZHMUi001-A) by reprogramming peripheral blood mononuclear cells from a 47, XXX syndrome patient
Published in Stem cell research (01-08-2017)“…47, XXX syndrome is one of several sex-chromosomal aneuploidies, and it has an incidence of approximately 1/1000 in newborn females. Because of heterogeneity…”
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Generation of GZKHQi001-A and GZWWTi001-A, two induced pluripotent stem cell lines derived from peripheral blood mononuclear cells of Duchenne muscular dystrophy patients
Published in Stem cell research (01-04-2018)“…Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in the DMD gene, which spans ~2.4Mb of genomic sequence at locus Xp21. This…”
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The Combination of CRISPR/Cas9 and iPSC Technologies in the Gene Therapy of Human β-thalassemia in Mice
Published in Scientific reports (01-09-2016)“…β-thalassemia results from point mutations or small deletions in the β-globin ( HBB ) gene that ultimately cause anemia. The generation of induced pluripotent…”
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CRISPR/Cas9-mediated β-globin gene knockout in rabbits recapitulates human β-thalassemia
Published in The Journal of biological chemistry (01-01-2021)“…β-thalassemia, an autosomal recessive blood disorder that reduces the production of hemoglobin, is majorly caused by the point mutation of the HBB gene…”
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The safety and effectiveness of genetically corrected iPSCs derived from [beta]-thalassaemia patients in nonmyeloablative [beta]-thalassaemic mice
Published in Stem cell research & therapy (16-07-2020)“…Background [beta]-Thalassaemia is a clinically common cause of hereditary haemolytic anaemia stemming from mutations in important functional regions of the…”
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10
Antioxidants retard the ageing of mouse oocytes
Published in Molecular medicine reports (01-08-2018)“…The aim of the present study was to verify the effects of heavy metal coupling agents (sodium citrate and EDTA) and antioxidants (acetyl carnitine and lipoic…”
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11
The Combination of CRISPR/Cas9 and iPSC Technologies in the Gene Therapy of Human [beta]-thalassemia in Mice
Published in Scientific reports (01-09-2016)“…β-thalassemia results from point mutations or small deletions in the β-globin (HBB) gene that ultimately cause anemia. The generation of induced pluripotent…”
Get full text
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