Search Results - "Yeung, Jennifer"

Mechanisms of adhesion G protein–coupled receptor activation by Vizurraga, Alexander, Adhikari, Rashmi, Yeung, Jennifer, Yu, Maiya, Tall, Gregory G.

“…Adhesion G protein–coupled receptors (AGPCRs) are a thirty-three-member subfamily of Class B GPCRs that control a wide array of physiological processes and are…”
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Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics by Tourdot, Benjamin E, Stoveken, Hannah, Trumbo, Derek, Yeung, Jennifer, Kanthi, Yogendra, Edelstein, Leonard C, Bray, Paul F, Tall, Gregory G, Holinstat, Michael

“…OBJECTIVE—Platelet activation after stimulation of PAR (protease-activated receptor) 4 is heightened in platelets from blacks compared with those from whites…”
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Liposomal bupivacaine decreases pain following retropubic sling placement: a randomized placebo-controlled trial by Mazloomdoost, Donna, Pauls, Rachel N., Hennen, Erin N., Yeung, Jennifer Y., Smith, Benjamin C., Kleeman, Steven D., Crisp, Catrina C.

“…Midurethral slings are commonly used to treat stress urinary incontinence. Pain control, however, may be a concern. Liposomal bupivacaine is a local anesthetic…”
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12-lipoxygenase: a potential target for novel anti-platelet therapeutics by Yeung, Jennifer, Holinstat, Michael

“…Platelets play an essential role in the regulation of hemostasis and thrombosis and controlling their level of activation is central to prevention of occlusive…”
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Pain and embarrassment associated with urodynamic testing in women by Yeung, Jennifer Y., Eschenbacher, Michaela A., Pauls, Rachel N.

“…Introduction Multichannel urodynamics is a series of interactive tests used to evaluate lower urinary tract dysfunction. We sought to describe symptoms and…”
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MRI-Based Predictors of Hemorrhagic Transformation in Patients With Stroke Treated by Intravenous Thrombolysis by El Nawar, Rody, Yeung, Jennifer, Labreuche, Julien, Chadenat, Marie-Laure, Duong, Duc Long, De Malherbe, Maxime, Cordoliani, Yves-Sebastien, Lapergue, Bertrand, Pico, Fernando

“…Clinical and biological risk factors for hemorrhagic transformation (HT) after intravenous thrombolysis (IT) have been well-established in several registries…”
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Anatomy of the Vulva and the Female Sexual Response by Yeung, Jennifer, DO, Pauls, Rachel N., MD

“…The female vulva is an intricate structure comprising several components. Each structure has been described separately, but the interplay among them and…”
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12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity by Yeung, J, Apopa, P L, Vesci, J, Stolla, M, Rai, G, Simeonov, A, Jadhav, A, Fernandez-Perez, P, Maloney, D J, Boutaud, O, Holman, T R, Holinstat, M

“…Following initial platelet activation, arachidonic acid is metabolised by cyclooxygenase-1 and 12-lipoxygenase (12-LOX). While the role of 12-LOX in the…”
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Fatty acids negatively regulate platelet function through formation of noncanonical 15‐lipoxygenase‐derived eicosanoids by Yamaguchi, Adriana, Hoorebeke, Christopher, Tourdot, Benjamin E., Perry, Steven C., Lee, Grace, Rhoads, Nicole, Rickenberg, Andrew, Green, Abigail R., Sorrentino, James, Yeung, Jennifer, Freedman, J. Cody, Holman, Theodore R., Holinstat, Michael

“…The antiplatelet effect of polyunsaturated fatty acids is primarily attributed to its metabolism to bioactive metabolites by oxygenases, such as lipoxygenases…”
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The Effect of Intravenous Acetaminophen on Postoperative Pain and Narcotic Consumption After Vaginal Reconstructive Surgery: A Double-Blind Randomized Placebo-Controlled Trial by Crisp, Catrina C, Khan, Madiha, Lambers, Donna L, Westermann, Lauren B, Mazloomdoost, Donna M, Yeung, Jennifer J, Kleeman, Steven D, Pauls, Rachel N

“…OBJECTIVEThis study aimed to determine the effect of intravenous acetaminophen versus placebo on postoperative pain, satisfaction with pain control, and…”
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Platelet Signaling and Disease: Targeted Therapy for Thrombosis and Other Related Diseases by Yeung, Jennifer, Li, Wenjie, Holinstat, Michael

“…Platelets are essential for clotting in the blood and maintenance of normal hemostasis. Under pathologic conditions such as atherosclerosis, vascular injury…”
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Investigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation1[S] by Ikei, Kenneth N., Yeung, Jennifer, Apopa, Patrick L., Ceja, Jesús, Vesci, Joanne, Holman, Theodore R., Holinstat, Michael

“…Human platelet-type 12-lipoxygenase (12-LOX) has recently been shown to play an important role in regulation of human platelet function by reacting with…”
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LMP4 regulates Tbx5 protein subcellular localization and activity by Camarata, Troy, Bimber, Benjamin, Kulisz, Andre, Chew, Teng-Leong, Yeung, Jennifer, Simon, Hans-Georg

“…The limb- and heart-specific Tbx5 transcription factor coexpresses with and directly binds to the novel PDZ-LIM domain protein, LMP4. LMP4 is distributed in…”
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The expansive role of oxylipins on platelet biology by Yeung, Jennifer, Hawley, Megan, Holinstat, Michael

“…In mammals, three major oxygenases, cyclooxygenases (COXs), lipoxygenases (LOXs), and cytochrome P450 (CYP450), generate an assortment of unique lipid…”
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A role for the histone deacetylase HDAC4 in the life-cycle of HIV-1-based vectors by Smith, Johanna A, Yeung, Jennifer, Kao, Gary D, Daniel, René

“…HIV-1 integration is mediated by the HIV-1 integrase protein, which joins 3'-ends of viral DNA to host cell DNA. To complete the integration process, HIV-1 DNA…”
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Who is the real 12-HETrE? by Yeung, Jennifer, Holinstat, Michael

“…•Structurally distinct 12-HETrE structures derived from platelet 12-LOX and CYP450.•12(S)-HETrE derived from platelet 12-LOX oxidation of DGLA is…”
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Discovery of First‐in‐Class Small Molecule Adhesion GPCR Modulators by Vizurraga, Alexander, Yeung, Jennifer, Tall, Gregory

“…Abstract only GPR56 (ADGRG1) is a member of a subset of G protein coupled receptors called adhesion GPCRs (AGPCRs). These GPCRs are unique in their possession…”
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An Individualized Countermeasure Assessment Framework for Astronauts in Space by Yeung, Jennifer, McGregor, Carolyn

“…Preventive measures and countermeasure exercises play integral roles in maintaining the physiological health, wellbeing, and performance of astronauts in…”
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Working Title: Who is the real 12-HETrE? by Yeung, Jennifer, Holinstat, Michael

“…Oxygenases, including lipoxygenases and cytochrome P450s, generate an array of structurally diverse oxylipins that modulate distinct biological responses in…”
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GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force by Yeung, Jennifer, Adili, Reheman, Stringham, Emily N., Luo, Rong, Vizurraga, Alexander, Rosselli-Murai, Luciana K., Stoveken, Hannah M., Yu, Maiya, Piao, Xianhua, Holinstat, Michael, Tall, Gregory G.

“…Circulating platelets roll along exposed collagen at vessel injury sites and respond with filipodia protrusion, shape change, and surface area expansion to…”
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