Search Results - "Yeung, Jake"

Oscillating and stable genome topologies underlie hepatic physiological rhythms during the circadian cycle by Mermet, Jérôme, Yeung, Jake, Naef, Felix

“…The circadian clock drives extensive temporal gene expression programs controlling daily changes in behavior and physiology. In mouse liver, transcription…”
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Sleep–wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex by Hor, Charlotte N., Yeung, Jake, Jan, Maxime, Emmenegger, Yann, Hubbard, Jeffrey, Xenarios, Ioannis, Naef, Felix, Franken, Paul

“…The timing and duration of sleep results from the interaction between a homeostatic sleep–wake-driven process and a periodic circadian process, and involves…”
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Cross-regulatory circuits linking inflammation, high-fat diet, and the circadian clock by Gachon, Frédéric, Yeung, Jake, Naef, Felix

“…Mammalian physiology resonates with the daily changes in the external environment, allowing processes such as rest-activity cycles, metabolism, and body…”
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Transcription factor activity rhythms and tissue-specific chromatin interactions explain circadian gene expression across organs by Yeung, Jake, Mermet, Jérôme, Jouffe, Céline, Marquis, Julien, Charpagne, Aline, Gachon, Frédéric, Naef, Felix

“…Temporal control of physiology requires the interplay between gene networks involved in daily timekeeping and tissue function across different organs. How the…”
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Clock-dependent chromatin topology modulates circadian transcription and behavior by Mermet, Jérôme, Yeung, Jake, Hurni, Clémence, Mauvoisin, Daniel, Gustafson, Kyle, Jouffe, Céline, Nicolas, Damien, Emmenegger, Yann, Gobet, Cédric, Franken, Paul, Gachon, Frédéric, Naef, Félix

“…The circadian clock in animals orchestrates widespread oscillatory gene expression programs, which underlie 24-h rhythms in behavior and physiology. Several…”
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Circadian clock-dependent and -independent posttranscriptional regulation underlies temporal mRNA accumulation in mouse liver by Wang, Jingkui, Symul, Laura, Yeung, Jake, Gobet, Cédric, Sobel, Jonathan, Lück, Sarah, Westermark, Pål O., Molina, Nacho, Naef, Felix

“…The mammalian circadian clock coordinates physiology with environmental cycles through the regulation of daily oscillations of gene expression. Thousands of…”
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The circadian oscillator analysed at the single‐transcript level by Phillips, Nicholas E, Hugues, Alice, Yeung, Jake, Durandau, Eric, Nicolas, Damien, Naef, Felix

“…The circadian clock is an endogenous and self‐sustained oscillator that anticipates daily environmental cycles. While rhythmic gene expression of circadian…”
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Rhythms of the Genome: Circadian Dynamics from Chromatin Topology, Tissue-Specific Gene Expression, to Behavior by Yeung, Jake, Naef, Felix

“…Circadian rhythms in physiology and behavior evolved to resonate with daily cycles in the external environment. In mammals, organs orchestrate temporal…”
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TCTAP C-093 “Break the Calcium Rock” - A Challenging Case of Calcified Left Main Bifurcation Lesion With Rotashock and Impella Support in an Elderly Patient by Jake Yeung, Yin Kei, Chan, Alan, Kang-Yin Lee, Michael

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Systems Chronobiology: Global Analysis of Gene Regulation in a 24-Hour Periodic World by Mermet, Jérôme, Yeung, Jake, Naef, Felix

“…Mammals have evolved an internal timing system, the circadian clock, which synchronizes physiology and behavior to the daily light and dark cycles of the…”
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The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism by Weger, Benjamin D., Gobet, Cédric, Yeung, Jake, Martin, Eva, Jimenez, Sonia, Betrisey, Bertrand, Foata, Francis, Berger, Bernard, Balvay, Aurélie, Foussier, Anne, Charpagne, Aline, Boizet-Bonhoure, Brigitte, Chou, Chieh Jason, Naef, Felix, Gachon, Frédéric

“…The circadian clock and associated feeding rhythms have a profound impact on metabolism and the gut microbiome. To what extent microbiota reciprocally affect…”
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scChIX-seq infers dynamic relationships between histone modifications in single cells by Yeung, Jake, Florescu, Maria, Zeller, Peter, de Barbanson, Buys Anton, Wellenstein, Max D., van Oudenaarden, Alexander

“…Regulation of chromatin states involves the dynamic interplay between different histone modifications to control gene expression. Recent advances have enabled…”
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Single-cell sortChIC identifies hierarchical chromatin dynamics during hematopoiesis by Zeller, Peter, Yeung, Jake, Viñas Gaza, Helena, de Barbanson, Buys Anton, Bhardwaj, Vivek, Florescu, Maria, van der Linden, Reinier, van Oudenaarden, Alexander

“…Post-translational histone modifications modulate chromatin activity to affect gene expression. How chromatin states underlie lineage choice in single cells is…”
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Floating IVUS Technique for Accurate Placement of Aorto-Ostial Stent by Leung, Calvin, Ho, Cheuk Bong, Wong, Ivan Man Ho, Yeung, Jake Yin Kei, Chan, Alan Ka Chun, Lee, Michael Kang Yin

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Single-Access Impella-Assisted Sheathless Antegrade and Retrograde Interventions of CTO: The SISARI Technique by Wong, Ivan, Leung, Calvin, Yeung, Jake Yin Kei, Fong, Esmond Yan Hang, Chan, Alan Ka Chun, Chan, Kam Tim, Lee, Michael Kang-Yin

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Single-Access Impella-Assisted Sheathless Antegrade and Retrograde Interventions of CTO by Wong, Ivan, Leung, Calvin, Yeung, Jake Yin Kei, Fong, Esmond Yan Hang, Chan, Alan Ka Chun, Chan, Kam Tim, Lee, Michael Kang-Yin

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HIT'nDRIVE: patient-specific multidriver gene prioritization for precision oncology by Shrestha, Raunak, Hodzic, Ermin, Sauerwald, Thomas, Dao, Phuong, Wang, Kendric, Yeung, Jake, Anderson, Shawn, Vandin, Fabio, Haffari, Gholamreza, Collins, Colin C, Sahinalp, S Cenk

“…Prioritizing molecular alterations that act as drivers of cancer remains a crucial bottleneck in therapeutic development. Here we introduce HIT'nDRIVE, a…”
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Heterogeneity in the inter-tumor transcriptome of high risk prostate cancer by Wyatt, Alexander W, Mo, Fan, Wang, Kendric, McConeghy, Brian, Brahmbhatt, Sonal, Jong, Lina, Mitchell, Devon M, Johnston, Rebecca L, Haegert, Anne, Li, Estelle, Liew, Janet, Yeung, Jake, Shrestha, Raunak, Lapuk, Anna V, McPherson, Andrew, Shukin, Robert, Bell, Robert H, Anderson, Shawn, Bishop, Jennifer, Hurtado-Coll, Antonio, Xiao, Hong, Chinnaiyan, Arul M, Mehra, Rohit, Lin, Dong, Wang, Yuzhuo, Fazli, Ladan, Gleave, Martin E, Volik, Stanislav V, Collins, Colin C

“…Genomic analyses of hundreds of prostate tumors have defined a diverse landscape of mutations and genome rearrangements, but the transcriptomic effect of this…”
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