Search Results - "Yeroslaviz, Assa"
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Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment
Published in Nature cell biology (01-08-2016)“…Tissue mechanics drive morphogenesis, but how forces are sensed and transmitted to control stem cell fate and self-organization remains unclear. We show that a…”
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2
Compromised Mitochondrial Protein Import Acts as a Signal for UPRmt
Published in Cell reports (Cambridge) (13-08-2019)“…The induction of the mitochondrial unfolded protein response (UPRmt) results in increased transcription of the gene encoding the mitochondrial chaperone HSP70…”
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3
Mitochondrial fusion is required for regulation of mitochondrial DNA replication
Published in PLoS genetics (06-06-2019)“…Mitochondrial dynamics is an essential physiological process controlling mitochondrial content mixing and mobility to ensure proper function and localization…”
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4
A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle
Published in eLife (30-05-2018)“…Muscles organise pseudo-crystalline arrays of actin, myosin and titin filaments to build force-producing sarcomeres. To study sarcomerogenesis, we have…”
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β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4
Published in Cell reports (Cambridge) (28-11-2023)“…Fibrosis, characterized by sustained activation of myofibroblasts and excessive extracellular matrix (ECM) deposition, is known to be associated with chronic…”
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The cytoplasmic poly(A) polymerases GLD-2 and GLD-4 promote general gene expression via distinct mechanisms
Published in Nucleic acids research (13-10-2014)“…Post-transcriptional gene regulation mechanisms decide on cellular mRNA activities. Essential gatekeepers of post-transcriptional mRNA regulation are broadly…”
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The complete and fully assembled genome sequence of Aeromonas salmonicida subsp. pectinolytica and its comparative analysis with other Aeromonas species: investigation of the mobilome in environmental and pathogenic strains
Published in BMC genomics (05-01-2018)“…Due to the predominant usage of short-read sequencing to date, most bacterial genome sequences reported in the last years remain at the draft level. This…”
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8
STAT3β is a tumor suppressor in acute myeloid leukemia
Published in Blood advances (09-07-2019)“…Signal transducer and activator of transcription 3 (STAT3) exists in 2 alternatively spliced isoforms, STAT3α and STAT3β. Although truncated STAT3β was…”
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Stage-specific combinations of opposing poly(A) modifying enzymes guide gene expression during early oogenesis
Published in Nucleic acids research (18-11-2019)“…Abstract RNA-modifying enzymes targeting mRNA poly(A) tails are universal regulators of post-transcriptional gene expression programs. Current data suggest…”
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The Integrated RNA Landscape of Renal Preconditioning against Ischemia-Reperfusion Injury
Published in Journal of the American Society of Nephrology (01-04-2020)“…Although AKI lacks effective therapeutic approaches, preventive strategies using preconditioning protocols, including caloric restriction and hypoxic…”
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Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity
Published in Cell reports (Cambridge) (06-12-2016)“…Fungal infections are major causes of morbidity and mortality, especially in immunocompromised individuals. The innate immune system senses fungal pathogens…”
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The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle
Published in EMBO reports (01-02-2015)“…In Drosophila , fibrillar flight muscles (IFMs) enable flight, while tubular muscles mediate other body movements. Here, we use RNA‐sequencing and…”
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13
Genome-wide RNAi screen for regulators of UPRmt in Caenorhabditis elegans mutants with defects in mitochondrial fusion
Published in G3 : genes - genomes - genetics (14-07-2021)“…Mitochondrial dynamics plays an important role in mitochondrial quality control and the adaptation of metabolic activity in response to environmental changes…”
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14
Compromised Mitochondrial Protein Import Acts as a Signal for UPR mt
Published in Cell reports (Cambridge) (13-08-2019)“…The induction of the mitochondrial unfolded protein response (UPR ) results in increased transcription of the gene encoding the mitochondrial chaperone HSP70…”
Get full text
Journal Article