Search Results - "Yeow, Yen"
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Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones
Published in Nature communications (03-04-2024)“…High-grade serous ovarian carcinoma (HGSOC) is genetically unstable and characterised by the presence of subclones with distinct genotypes. Intratumoural…”
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A novel stress sensor enables accurate estimation of micro-scale tissue mechanics in quantitative micro-elastography
Published in APL bioengineering (01-09-2024)“…Quantitative micro-elastography (QME) is a compression-based optical coherence elastography technique enabling the estimation of tissue mechanical properties…”
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Injury to the tunica media initiates atherogenesis in the presence of hyperlipidemia
Published in Frontiers in cardiovascular medicine (30-03-2023)“…Fatty streaks initiating the formation of atheromatous plaque appear in the tunica intima. The tunica media is not known to be a nidus for lipid accumulation…”
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ECM Depletion Is Required to Improve the Intratumoral Uptake of Iron Oxide Nanoparticles in Poorly Perfused Hepatocellular Carcinoma
Published in Frontiers in oncology (22-02-2022)“…Improving tumor access for drug delivery is challenging, particularly in poorly perfused tumors. The availability of functional tumor blood vessels for…”
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Immune‐mediated ECM depletion improves tumour perfusion and payload delivery
Published in EMBO molecular medicine (01-12-2019)“…High extracellular matrix (ECM) content in solid cancers impairs tumour perfusion and thus access of imaging and therapeutic agents. We have devised a new…”
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Enhanced Detection of Desmoplasia by Targeted Delivery of Iron Oxide Nanoparticles to the Tumour-Specific Extracellular Matrix
Published in Pharmaceutics (12-10-2021)“…Diagnostic imaging of aggressive cancer with a high stroma content may benefit from the use of imaging contrast agents targeted with peptides that have high…”
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Ultrahigh-resolution optical coherence elastography through a micro-endoscope: towards in vivo imaging of cellular-scale mechanics
Published in Biomedical optics express (01-11-2017)“…In this paper, we describe a technique capable of visualizing mechanical properties at the cellular scale deep in living tissue, by incorporating a…”
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Brain and spinal tumour
Published in Medical journal of Malaysia (01-12-2014)“…This study reviewed the epidemiology of brain and spinal tumours in Sarawak from January 2009 till December 2012. The crude incidence of brain tumour in…”
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Antecedents of the responsible acquisition of computers behaviour: Integrating the theory of planned behaviour with the value-belief-norm theory and the habits variable
Published in PloS one (02-06-2023)“…The responsible behaviour of consumers that purchase green computers is a form of sustainable consumption, as green computers use less energy resulting in less…”
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Solar and Battery Sizing for Maximum Savings Implementation in Malaysia's Buildings
Published in 2021 IEEE International Future Energy Electronics Conference (IFEEC) (16-11-2021)“…In the wake of global warming, the need to speed up the adoption of renewable energy is crucial. However, due to the absence of awareness of the financial…”
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