Search Results - "Yeow, Wen‐Shuz"

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression by Sharma, Ankur, Yeow, Wen-Shuz, Ertel, Adam, Coleman, Ilsa, Clegg, Nigel, Thangavel, Chellappagounder, Morrissey, Colm, Zhang, Xiaotun, Comstock, Clay E S, Witkiewicz, Agnieszka K, Gomella, Leonard, Knudsen, Erik S, Nelson, Peter S, Knudsen, Karen E

“…Retinoblastoma (RB; encoded by RB1) is a tumor suppressor that is frequently disrupted in tumorigenesis and acts in multiple cell types to suppress cell cycle…”
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Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells by Izaguirre, Alexander, Barnes, Betsy J., Amrute, Sheela, Yeow, Wen‐Shuz, Megjugorac, Nicholas, Dai, Jihong, Feng, Di, Chung, Eugene, Pitha, Paula M., Fitzgerald‐Bocarsly, Patricia

“…Plasmacytoid dendritic cells (PDC) produce high levels of type I IFN upon stimulation with viruses, while monocytes and monocyte‐derived dendritic cells (MDDC)…”
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Functional Analysis of Human Herpesvirus 8-Encoded Viral Interferon Regulatory Factor 1 and Its Association with Cellular Interferon Regulatory Factors and p300 by Burýsek, L, Yeow, W S, Lubyová, B, Kellum, M, Schafer, S L, Huang, Y Q, Pitha, P M

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Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin by Tsai, Wilson S, Yeow, Wen-Shuz, Chua, Alex, Reddy, Rishindra M, Nguyen, Duc M, Schrump, David S, Nguyen, Dao M

“…Although expressing adequate levels of functional tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) receptors DR4/DR5, significant proportion of…”
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Valproic Acid, an Antiepileptic Drug with Histone Deacetylase Inhibitory Activity, Potentiates the Cytotoxic Effect of Apo2L/TRAIL on Cultured Thoracic Cancer Cells through Mitochondria-Dependent Caspase Activation by Ziauddin, M. Firdos, Yeow, Wen-Shuz, Maxhimer, Justin B., Baras, Aris, Chua, Alex, Reddy, Rishindra M., Tsai, Wilson, Cole, George W., Schrump, David S., Nguyen, Dao M.

“…Inhibitors of histone deacetylases have been shown to enhance the sensitivity of cancer cells to tumor necrosis factor-related apoptosis-inducing ligand…”
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The Canonical NF-κB Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion by Liu, Manran, Sakamaki, Toshiyuki, Casimiro, Mathew C., Willmarth, Nicole E., Quong, Andrew A., Ju, Xiaoming, Ojeifo, John, Jiao, Xuanmao, Yeow, Wen-Shuz, Katiyar, Sanjay, Shirley, L. Andrew, Joyce, David, Lisanti, Michael P., Albanese, Christopher, Pestell, Richard G.

“…The role of mammary epithelial cell (MEC) NF-κB in tumor progression in vivo is unknown, as murine NF-κB components and kinases either are required for murine…”
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Cyclin D1/Cyclin-Dependent Kinase 4 Interacts with Filamin A and Affects the Migration and Invasion Potential of Breast Cancer Cells by ZHIJIU ZHONG, YEOW, Wen-Shuz, CHUNHUA ZOU, WASSELL, Richard, CHENGUANG WANG, PESTELL, Richard G, QUONG, Judy N, QUONG, Andrew A

“…Cyclin D1 belongs to a family of proteins that regulate progression through the G1-S phase of the cell cycle by binding to cyclin-dependent kinase (cdk)-4 to…”
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Regulation of DNA-Raised Immune Responses by Cotransfected Interferon Regulatory Factors by Sasaki, Shin, Amara, Rama Rao, Yeow, Wen-Shuz, Pitha, Paula M, Robinson, Harriet L

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The essential role of the mitochondria-dependent death-signaling cascade in chemotherapy-induced potentiation of Apo2L/TRAIL cytotoxicity in cultured thoracic cancer cells: amplified caspase 8 is indispensable for combination-mediated massive cell death by Nguyen, Dao M, Yeow, Wen-Shuz, Ziauddin, M Firdos, Baras, Aris, Tsai, Wilson, Reddy, Rishindra M, Chua, Alex, Cole, Jr, George W, Schrump, David S

“…Despite adequately expressing functional receptors for tumor necrosis factor receptor apoptosis-inducing ligand (TRAIL), many cultured tumor cells are…”
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Suppression of Pro-metastasis Phenotypes Expression in Malignant Pleural Mesothelioma by the PI3K Inhibitor LY294002 or the MEK Inhibitor UO126 by COLE, George W, ALLEVA, Annette M, ZUO, Jing T, SEHGAL, Shailen S, YEOW, Wen-Shuz, SCHRUMP, David S, NGUYEN, Dao M

“…Background: This study aimed to evaluate the impact of selective abrogation of either the MEK/ERK1/2 (UO126 or PD98059) or the PI3K/AKT (LY294002) signaling…”
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Disruption of a Sirt1-Dependent Autophagy Checkpoint in the Prostate Results in Prostatic Intraepithelial Neoplasia Lesion Formation by POWELL, Michael J, CASIMIRO, Mathew C, CORDON-CARDO, Carlos, XIAOHONG HE, YEOW, Wen-Shuz, CHENGUANG WANG, MCCUE, Peter A, MCBURNEY, Michael W, PESTELL, Richard G

“…The Sirtuin family of proteins (SIRT) encode a group of evolutionarily conserved, NAD-dependent histone deacetylases, involved in many biological pathways…”
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Expression of biologically active human interferon alpha 2 in Aloe vera by Lowther, William, Lorick, Kevin, Lawrence, Susan D, Yeow, Wen-Shuz

“…Methods necessary for the successful transformation and regeneration of Aloe vera were developed and used to express the human protein, interferon alpha 2…”
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The Cell Fate Determination Factor DACH1 Is Expressed in Estrogen Receptor-α-Positive Breast Cancer and Represses Estrogen Receptor-α Signaling by POPOV, Vladimir M, JIE ZHOU, KUMAR, Rakesh, CHENGUANG WANG, PESTELL, Richard G, ANDREW SHIRLEY, L, QUONG, Judy, YEOW, Wen-Shuz, WRIGHT, Jennifer A, KONGMING WU, RUI, Hallgeir, VADLAMUDI, Ratna K, JIE JIANG

“…The Dachshund (dac) gene, initially cloned as a dominant inhibitor of the Drosophila hyperactive EGFR mutant ellipse, encodes a key component of the cell fate…”
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Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor–related apoptosis-inducing ligand by Yeow, Wen-Shuz, Baras, Aris, Chua, Alex, Nguyen, Duc M., Sehgal, Shailen S., Schrump, David S., Nguyen, Dao M.

“…Chemotherapeutic agents sensitize cancer cells to Apo2 ligand/tumor necrosis factor–related apoptosis-inducing ligand (Apo2L/TRAIL) via recruitment of the…”
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Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade by Reddy, Rishindra M, Yeow, Wen-Shuz, Chua, Alex, Nguyen, Duc M, Baras, Aris, Ziauddin, M Firdos, Shamimi-Noori, Susan M, Maxhimer, Justin B, Schrump, David S, Nguyen, Dao M

“…Apo2L/TRAIL is actively investigated as a novel targeted agent to directly induce apoptosis of susceptible cancer cells. Apo2L/TRAIL-refractory cells can be…”
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Reconstitution of Virus-mediated Expression of Interferon α Genes in Human Fibroblast Cells by Ectopic Interferon Regulatory Factor-7 by Yeow, Wen-Shuz, Au, Wei-Chun, Juang, Yuang-Taung, Fields, Cindy D., Dent, Carolyn L., Gewert, Dirk R., Pitha, Paula M.

“…Type I interferons constitute an important part of the innate immune response against viral infection. Unlike the expression of interferon (IFN) B gene, the…”
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Antiviral activities of individual murine IFN-alpha subtypes in vivo: intramuscular injection of IFN expression constructs reduces cytomegalovirus replication by Yeow, W S, Lawson, C M, Beilharz, M W

“…The IFN-alpha cytokines belong to a multigene family. However, the in vivo biological functions of each of the IFN-alpha subtypes is unknown. Recently, we…”
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Downregulation of IRF-3 Levels by Ribozyme Modulates the Profile of IFNA Subtypes Expressed in Infected Human Cells by Yeow, W S, Au, W C, Lowther, W J, Pitha, P M

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Regulation of the Promoter Activity of Interferon Regulatory Factor-7 Gene by Lu, Runqing, Au, Wei-Chun, Yeow, Wen-Shuz, Hageman, Nathan, Pitha, Paula M.

“…The molecular mechanism by which virus induces expression of the early inflammatory genes has not yet been completely elucidated. Previous studies indicated…”
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The in vitro expression patterns of individual type I interferon genes in newcastle disease virus infected murine splenocytes and fibroblasts by Yeow, Wen-Shuz, Beilharz, Manfred W., Lai, C.May

“…Murine type I interferon levels present in mice sera following Newcastle disease virus infections are influenced by the If-1 locus. Sera interferon levels in…”
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