Search Results - "Yeow, Tan Boon"
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Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial
Published in The American journal of medicine (01-11-2015)“…Abstract Background It is important to establish whether frailty among older individuals is reversible with nutritional, physical, or cognitive interventions,…”
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2
Plasma osteopontin as a biomarker of Alzheimer’s disease and vascular cognitive impairment
Published in Scientific reports (17-02-2021)“…Cerebrovascular disease (CeVD) and neurodegenerative dementia such as Alzheimer’s disease (AD) are frequently associated comorbidities in the elderly, sharing…”
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3
White matter microstructural abnormalities and default network degeneration are associated with early memory deficit in Alzheimer’s disease continuum
Published in Scientific reports (18-03-2019)“…Instead of assuming a constant relationship between brain abnormalities and memory impairment, we aimed to examine the stage-dependent contributions of…”
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4
Distinct BOLD variability changes in the default mode and salience networks in Alzheimer’s disease spectrum and associations with cognitive decline
Published in Scientific reports (15-04-2020)“…Optimal levels of intrinsic Blood-Oxygenation-Level-Dependent (BOLD) signal variability (variability hereafter) are important for normative brain functioning…”
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Risk Factors for and Clinical Relevance of Incident and Progression of Cerebral Small Vessel Disease Markers in an Asian Memory Clinic Population
Published in Journal of Alzheimer's disease (01-01-2019)“…Cerebral small vessel disease (SVD) is one of the major contributors to cognitive impairment and dementia. However, data on the incidence and progression of…”
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6
Cortical microinfarcts on 3T MRI: Clinical correlates in memory-clinic patients
Published in Alzheimer's & dementia (01-12-2015)“…Abstract Introduction This is the first study to assess cerebral microinfarcts (CMIs) on 3 tesla (3T) magnetic resonance imaging (MRI) in a memory clinic…”
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7
FTIR studies of the curing reactions of palm oil alkyd-melamine enamels
Published in Journal of applied polymer science (20-06-2001)“…Three alkyds of high hydroxyl numbers with oil lengths of 21, 30, and 41 were prepared from crude palm oil. The excess hydroxyl groups provided good…”
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8
Cerebral microinfarcts affect brain structural network topology in cognitively impaired patients
Published in Journal of cerebral blood flow and metabolism (01-01-2021)“…Cerebral microinfarcts (CMIs), a novel cerebrovascular marker, are prevalent in Alzheimer’s disease (AD) and associated with cognitive impairment. Nonetheless,…”
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Inter-hemispheric functional dysconnectivity mediates the association of corpus callosum degeneration with memory impairment in AD and amnestic MCI
Published in Scientific reports (01-09-2016)“…Evidences suggested that both corpus callosum (CC) degeneration and alternations of homotopic inter-hemispheric functional connectivity (FC) are present in…”
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10
Effects of multi-domain lifestyle interventions on sarcopenia measures and blood biomarkers: secondary analysis of a randomized controlled trial of community-dwelling pre-frail and frail older adults
Published in Aging (Albany, NY.) (15-04-2021)“…Few studies have comprehensively described changes in blood biomarkers of the physiological responses underlying sarcopenia reduction associated with lifestyle…”
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Burden of informal care in stroke survivors and its determinants: a prospective observational study in an Asian setting
Published in BMC public health (26-10-2021)“…Abstract Background Informal caregiving is an integral part of post-stroke recovery with strenuous caregiving demands often resulting in caregiving burden,…”
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Cognitive Effects of Multi-Domain Interventions Among Pre-Frail and Frail Community-Living Older Persons: Randomized Controlled Trial
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (09-05-2018)“…Cognitive, physical, and nutritional interventions may produce different cognitive effects for different groups of older persons. We investigated…”
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13
Impact of Strategically Located White Matter Hyperintensities on Cognition in Memory Clinic Patients with Small Vessel Disease
Published in PloS one (08-11-2016)“…Studies on the impact of small vessel disease (SVD) on cognition generally focus on white matter hyperintensity (WMH) volume. The extent to which WMH location…”
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14
'I secretly wish. . .' Caregivers' expression of wish for death of persons with severe dementia
Published in Age and ageing (01-05-2024)“…Qualitative evidence suggests that caregivers may express a wish for death of persons with severe dementia (PwSD). No study has assessed the extent to which it…”
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Markers of Cardiac Dysfunction in Cognitive Impairment and Dementia
Published in Medicine (Baltimore) (01-01-2015)“…Markers of cardiac dysfunction such as amino terminal pro-brain natriuretic peptide (NTpro-BNP) and high sensitivity cardiac troponin T (hs-cTnT) may be…”
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Primary Care Prognostic (PCP) Index of 11-Year Mortality Risk: Development and Validation of a Brief Prognostic Tool
Published in Journal of general internal medicine : JGIM (01-01-2021)“…Background Healthcare providers use a life expectancy of at least 5 to 10 years in shared clinical decision-making with older adults about cancer screening,…”
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Interactive effect of diabetes mellitus and subclinical MRI markers of cerebrovascular disease on cognitive decline and incident dementia: a memory-clinic study
Published in Alzheimer's research & therapy (03-10-2024)“…Cognitive impairment is an increasingly recognized comorbidity of diabetes, yet the mechanisms underlying this association remain poorly understood. This…”
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Cerebrovascular disease influences functional and structural network connectivity in patients with amnestic mild cognitive impairment and Alzheimer's disease
Published in Alzheimer's research & therapy (18-08-2018)“…Patients with amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD) show functional and structural connectivity alterations in the default…”
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Healthcare utilization and cost trajectories post-stroke: role of caregiver and stroke factors
Published in BMC health services research (22-11-2018)“…It is essential to study post-stroke healthcare utilization trajectories from a stroke patient caregiver dyadic perspective to improve healthcare delivery,…”
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Qualitative study exploring heterogeneity in caregiving experiences post-stroke in Singapore
Published in BMJ open (15-03-2023)“…ObjectiveStroke, a common illness in older adults, accounts for up to 4% of direct medical costs in developed nations. Informal caregiving contributing a…”
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