Search Results - "Yeoh, Zoe C."
-
1
Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
Published in Cell (27-11-2019)“…Mammalian switch/sucrose non-fermentable (mSWI/SNF) complexes are multi-component machines that remodel chromatin architecture. Dissection of the subunit- and…”
Get full text
Journal Article -
2
Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy
Published in Cell (25-11-2020)“…Cancer therapies kill tumors either directly or indirectly by evoking immune responses and have been combined with varying levels of success. Here, we describe…”
Get full text
Journal Article -
3
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival
Published in The Journal of cell biology (04-01-2021)“…Complex neural circuitry requires stable connections formed by lengthy axons. To maintain these functional circuits, fast transport delivers RNAs to distal…”
Get full text
Journal Article -
4
Identification of a potent and selective covalent Pin1 inhibitor
Published in Nature chemical biology (01-09-2020)“…Peptidyl-prolyl cis / trans isomerase NIMA-interacting 1 (Pin1) is commonly overexpressed in human cancers, including pancreatic ductal adenocarcinoma (PDAC)…”
Get full text
Journal Article -
5
NMR chemical shift assignments of RNA oligonucleotides to expand the RNA chemical shift database
Published in Biomolecular NMR assignments (01-10-2021)“…RNAs play myriad functional and regulatory roles in the cell. Despite their significance, three-dimensional structure elucidation of RNA molecules lags…”
Get full text
Journal Article -
6
Intellectual disability-associated SMARCB1 mutations reveal a nucleosome acidic patch interaction site that potentiates mSWI/SNF chromatin remodeling
Published in Cell (20-11-2019)“…Mammalian SWI/SNF (BAF) complexes are multi-component machines that remodel chromatin architecture. Dissection of the subunit- and domain- specific…”
Get full text
Journal Article