Search Results - "Yeoh, Thean"

The Effect of Process Parameters on the Microstructure, Stability, and Sensorial Properties of an Emulsion Cream Formulation by Chow, Pui Shan, Lim, Ron Tau Yee, Cyriac, Febin, Shah, Jaymin C, Badruddoza, Abu Zayed Md, Yeoh, Thean, Yagnik, Chetan Kantilal, Tee, Xin Yi, Wong, Annie Bao Hua, Chia, Vernissa Dilys, Wang, Guan

“…A classical emulsion formulation based on petrolatum and mineral oil as the internal phase with emulsifier wax as a typical topical emulsion cream was…”
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Influence of Manufacturing Process on the Microstructure, Stability, and Sensorial Properties of a Topical Ointment Formulation by Chow, Pui Shan, Lim, Ron Tau Yee, Cyriac, Febin, Shah, Jaymin C, Badruddoza, Abu Zayed Md, Yeoh, Thean, Yagnik, Chetan Kantilal, Tee, Xin Yi, Wong, Annie Bao Hua, Chia, Vernissa Dilys, Wang, Guan

“…The manufacturing process for ointments typically involves a series of heating, cooling, and mixing steps. Precise control of the level of mixing through…”
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API-polymer interactions in Sepineo P600 based topical gel formulation- impact on rheology by Badruddoza, Abu Zayed Md, Yeoh, Thean, Shah, Jaymin C.

“…[Display omitted] In the present study, topical gel and emulsion gel were formulated using Acrylamide/ Sodium Acryloyldimethyl taurate copolymer (Sepineo P600)…”
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Topical drug delivery by Sepineo P600 emulgel: Relationship between rheology, physical stability, and formulation performance by Badruddoza, Abu Zayed Md, Zahid, Md Ikhtiar, Walsh, Taylor, Shah, Jaymin, Gates, Dana, Yeoh, Thean, Nurunnabi, Md

“…[Display omitted] The objective of this present work was to develop and optimize oil-in-water (O/W) emulsion-based gels, namely emulgels that allow maximum…”
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Semisolid Pharmaceutical Product Characterization Using Non-invasive X-ray Microscopy and AI-Based Image Analytics by Yeoh, Thean, Ma, Lisa, Badruddoza, Abu Zayed, Shah, Jaymin, Zhang, Shawn

“…This work reports the use of X-ray microscopy (XRM) imaging to characterize the microstructure of semisolid formulations containing multiple immiscible phases…”
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Ex vivo (human skin) and in vivo (minipig) permeation of propylene glycol applied as topical crisaborole ointment, 2 by Thombre, Avinash, Tse, Susanna, Yeoh, Thean, Chen, Raymond, North, Robert, Brown, Marc

“…[Display omitted] Crisaborole ointment, 2%, is a non-steroidal phosphodiesterase 4 inhibitor for the treatment of mild-to-moderate atopic dermatitis. It…”
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Crystallization and Rheology of Mono- and Diglycerides and Their Role in Stabilization of Emulsion Droplets in Model Topical Ointments by Ali, Samim, Tiwari, Anju, Yeoh, Thean, Doshi, Pankaj, Kelkar, Narayani, Shah, Jaymin C., Seth, Jyoti R.

“…The crystallization behavior of commercial mono- and diglycerides (MDG) in paraffin oil is studied to develop an in-depth understanding of the polymorphic…”
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Sustainable Alternatives to Petroleum-Derived Excipients in Pharmaceutical Oil-in-Water Creams by Gates, Dana, Badruddoza, Abu Zayed Md, Zahid, Md Ikhtiar, Yeoh, Thean, Shah, Jaymin, Walsh, Taylor, Nurunnabi, Md

“…Recently, vast efforts towards sustainability have been made in the pharmaceutical industry. In conventional oil-in-water (O/W) cream formulations, various…”
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Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model by Bodenlenz, Manfred, Yeoh, Thean, Berstein, Gabriel, Mathew, Shibin, Shah, Jaymin, Banfield, Christopher, Hollingshead, Brett, Steyn, Stefanus J., Osgood, Sarah M., Beaumont, Kevin, Kainz, Sonja, Holeček, Christian, Trausinger, Gert, Raml, Reingard, Birngruber, Thomas

“…Purpose Accurate methods to determine dermal pharmacokinetics are important to increase the rate of clinical success in topical drug development. We…”
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Correction: Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model by Bodenlenz, Manfred, Yeoh, Thean, Berstein, Gabriel, Mathew, Shibin, Shah, Jaymin, Banfield, Christopher, Hollingshead, Brett, Steyn, Stefanus J., Osgood, Sarah M., Beaumont, Kevin, Kainz, Sonja, Holeček, Christian, Trausinger, Gert, Raml, Reingard, Birngruber, Thomas

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Interplay of Aging and Lot-to-Lot Variability on the Physical and Chemical Properties of Excipients: A Case Study of Mono- and Diglycerides by Kushwah, Varun, Saraf, Isha, Yeoh, Thean, Ardelean, Ioan, Weber, Hansjoerg, Sarkar, Avik, Chen, Raymond, Vogel, Trevor, Modhave, Dattatray, Laggner, Peter, Paudel, Amrit

“…The present study investigates the chemical composition governing the physical properties of mono- and diglycerides (MDGs) at the microstructural level, as a…”
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Quantitative Chemical Profiling of Commercial Glyceride Excipients via 1H NMR Spectroscopy by Saraf, Isha, Kushwah, Varun, Weber, Hansjoerg, Modhave, Dattatray, Yeoh, Thean, Paudel, Amrit

“…Abstract Glycerides are the main components of oils, and fats, used in formulated products in the food and cosmetic industry as well as in the pharmaceutical…”
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Coalescence-induced phase separation of an oil in water emulsion under controlled shear and temperature conditions by Nadeem, Hannan, Vigil, R. Dennis, Samuel, Amanda, Sarkar, Avik, Yeoh, Thean, Olsen, Michael G.

“…Phase separation behavior was investigated in an oil-in-water type emulsion. A Couette flow cell was utilized for the phase separation experiments. The…”
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Skin permeation and penetration of crisaborole when coapplied with emollients by Draelos, Zoe D., Ports, William C., Vlahos, Bonnie, Yeoh, Thean, Wu-Linhares, Dan, Brown, Marc B., Lenn, Jon, Thombre, Avinash G.

“…[Display omitted]…”
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Current landscape and trends in transdermal drug delivery systems by Yeoh, Thean

“…"Generic pharmaceutical marketers are increasingly keen to have a presence in generic patches as they represent high-margin, high entry-barrier opportunities…”
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Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin by Jones, Peter, Storer, R. Ian, Sabnis, Yogesh A, Wakenhut, Florian M, Whitlock, Gavin A, England, Katherine S, Mukaiyama, Takasuke, Dehnhardt, Christoph M, Coe, Jotham W, Kortum, Steve W, Chrencik, Jill E, Brown, David G, Jones, Rhys M, Murphy, John R, Yeoh, Thean, Morgan, Paul, Kilty, Iain

“…By use of a structure-based computational method for identification of structurally novel Janus kinase (JAK) inhibitors predicted to bind beyond the ATP…”
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Continuous Manufacturing of Oil in Water (O/W) Emulgel by Extrusion Process by Echanur, V. Anusha, Matadh, Anusha V., Pragathi, S. G., Sarasija, S., Thean, Yeoh, Badruddoza, Abu Zayed, Shah, Jaymin, Kulkarni, Vijay, Ajjarapu, Srinivas, Reena, N. M., Shivakumar, H. N., Murthy, S. Narasimha

“…Pharmaceutical industries and drug regulatory agencies are inclining towards continuous manufacturing due to better control over the processing conditions and…”
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Current opportunities and challenges in intradermal vaccination by Chen, David, Bowersock, Terry, Weeratna, Risini, Yeoh, Thean

“…The skin is an attractive site for immunization in humans and animals, owing to its resident population of dendritic cells and macrophages along with extensive…”
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Minimization of CYP2D6 Polymorphic Differences and Improved Bioavailability via Transdermal Administration: Latrepirdine Example by Chew, Marci L., Mordenti, Joyce, Yeoh, Thean, Ranade, Gautam, Qiu, Ruolun, Fang, Juanzhi, Liang, Yali, Corrigan, Brian

“…Purpose Transdermal delivery has the potential to offer improved bioavailability by circumventing first-pass gut and hepatic metabolism. This study evaluated…”
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Quantitative Chemical Profiling of Commercial Glyceride Excipients via1H NMR Spectroscopy by Saraf, Isha, Kushwah, Varun, Weber, Hansjoerg, Modhave, Dattatray, Yeoh, Thean, Paudel, Amrit

“…Glycerides are the main components of oils, and fats, used in formulated products in the food and cosmetic industry as well as in the pharmaceutical product…”
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