Search Results - "Yeo, Robin W."

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging by Leeman, Dena S, Hebestreit, Katja, Ruetz, Tyson, Webb, Ashley E, McKay, Andrew, Pollina, Elizabeth A, Dulken, Ben W, Zhao, Xiaoai, Yeo, Robin W, Ho, Theodore T, Mahmoudi, Salah, Devarajan, Keerthana, Passegué, Emmanuelle, Rando, Thomas A, Frydman, Judith, Brunet, Anne

“…In the adult brain, the neural stem cell (NSC) pool comprises quiescent and activated populations with distinct roles. Transcriptomic analysis revealed that…”
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Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans by Daugherty, Aaron C, Yeo, Robin W, Buenrostro, Jason D, Greenleaf, William J, Kundaje, Anshul, Brunet, Anne

“…Chromatin accessibility, a crucial component of genome regulation, has primarily been studied in homogeneous and simple systems, such as isolated cell…”
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Self-sperm induce resistance to the detrimental effects of sexual encounters with males in hermaphroditic nematodes by Booth, Lauren N, Maures, Travis J, Yeo, Robin W, Tantilert, Cindy, Brunet, Anne

“…Sexual interactions have a potent influence on health in several species, including mammals. Previous work in identified strategies used by males to accelerate…”
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Aging and Rejuvenation of Neural Stem Cells and Their Niches by Navarro Negredo, Paloma, Yeo, Robin W., Brunet, Anne

“…Aging has a profound and devastating effect on the brain. Old age is accompanied by declining cognitive function and enhanced risk of brain diseases, including…”
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Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem cell adhesion and migration during aging by Yeo, Robin W, Zhou, Olivia Y, Zhong, Brian L, Sun, Eric D, Navarro Negredo, Paloma, Nair, Surag, Sharmin, Mahfuza, Ruetz, Tyson J, Wilson, Mikaela, Kundaje, Anshul, Dunn, Alexander R, Brunet, Anne

“…The regenerative potential of brain stem cell niches deteriorates during aging. Yet the mechanisms underlying this decline are largely unknown. Here we…”
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Males induce premature demise of the opposite sex by multifaceted strategies by Booth, Lauren N, Shi, Cheng, Tantilert, Cindy, Yeo, Robin W, Miklas, Jason W, Hebestreit, Katja, Hollenhorst, Cecilia N, Maures, Travis J, Buckley, Matthew T, Murphy, Coleen T, Brunet, Anne

“…Interactions between the sexes negatively impact health in many species. In Caenorhabditis, males shorten the lifespan of the opposite sex-hermaphrodites or…”
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CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells by Ruetz, Tyson J., Pogson, Angela N., Kashiwagi, Chloe M., Gagnon, Stephanie D., Morton, Bhek, Sun, Eric D., Na, Jeeyoon, Yeo, Robin W., Leeman, Dena S., Morgens, David W., Tsui, C. Kimberly, Li, Amy, Bassik, Michael C., Brunet, Anne

“…Ageing impairs the ability of neural stem cells (NSCs) to transition from quiescence to proliferation in the adult mammalian brain. Functional decline of NSCs…”
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Improving few-shot learning-based protein engineering with evolutionary sampling by Jawaid, M. Zaki, Yeo, Robin W, Gautam, Aayushma, Gainous, T. Blair, Hart, Daniel O, Daley, Timothy P

“…Designing novel functional proteins remains a slow and expensive process due to a variety of protein engineering challenges; in particular, the number of…”
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