Search Results - "Yeo, Mirae"

Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations by Lee, Stanley Chun-Wei, North, Khrystyna, Kim, Eunhee, Jang, Eunjung, Obeng, Esther, Lu, Sydney X., Liu, Bo, Inoue, Daichi, Yoshimi, Akihide, Ki, Michelle, Yeo, Mirae, Zhang, Xiao Jing, Kim, Min Kyung, Cho, Hana, Chung, Young Rock, Taylor, Justin, Durham, Benjamin H., Kim, Young Joon, Pastore, Alessandro, Monette, Sebastien, Palacino, James, Seiler, Michael, Buonamici, Silvia, Smith, Peter G., Ebert, Benjamin L., Bradley, Robert K., Abdel-Wahab, Omar

“…Mutations affecting RNA splicing factors are the most common genetic alterations in myelodysplastic syndrome (MDS) patients and occur in a mutually exclusive…”
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Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth by Choi, Hyukjun, Yeo, Mirae, Kang, Yujin, Kim, Hyo Jeong, Park, Seong Guk, Jang, Eunjung, Park, Sung Ho, Kim, Eunhee, Kang, Sebyung

“…The aggressive proliferation of tumor cells often requires increased glucose uptake and excessive anaerobic glycolysis, leading to the massive production and…”
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Akt enhances the vulnerability of cancer cells to VCP/p97 inhibition-mediated paraptosis by Lee, Dong Min, Kim, In Young, Lee, Hong Jae, Seo, Min Ji, Cho, Mi-Young, Lee, Hae In, Yoon, Gyesoon, Ji, Jae-Hoon, Park, Seok Soon, Jeong, Seong-Yun, Choi, Eun Kyung, Choi, Yong Hyeon, Yun, Chae-Ok, Yeo, Mirae, Kim, Eunhee, Choi, Kyeong Sook

“…Valosin-containing protein (VCP)/p97, an AAA+ ATPase critical for maintaining proteostasis, emerges as a promising target for cancer therapy. This study…”
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TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth by Jun, Heejin, Jang, Eunjung, Kim, Hansol, Yeo, Mirae, Park, Seong Guk, Lee, Jaehyeok, Shin, Kyeong Jin, Chae, Young Chan, Kang, Sebyung, Kim, Eunhee

“…The TNF-related apoptosis-inducing ligand (TRAIL) is a promising anticancer drug candidate because it selectively binds to the proapoptotic death receptors,…”
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CD13-targeting and TRAIL-displaying protein nanoparticles effectively induce apoptotic cell death of acute myeloid leukemia, prolonging survival in mouse models by Jun, Heejin, Yeo, Mirae, Jeon, Jun Pyo, Eom, Soomin, Kim, Hyo Jeong, Kim, Yunjung, Jang, Eunjung, Park, Sung Ho, Kim, Eunhee, Kang, Sebyung

“…Acute myeloid leukemia (AML) is a rapidly proliferating blood cancer, necessitating treatments that specifically target and swiftly eradicate it. In this…”
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Lactate oxidase/vSIRPα conjugates efficiently consume tumor-produced lactates and locally produce tumor-necrotic H2O2 to suppress tumor growth by Kang, Yujin, Yeo, Mirae, Choi, Hyukjun, Jun, Heejin, Eom, Soomin, Park, Seong Guk, Yoon, Haejin, Kim, Eunhee, Kang, Sebyung

“…Aggressive tumor formation often leads to excessive anaerobic glycolysis and massive production and accumulation of lactate in the tumor microenvironment…”
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Lactate oxidase/vSIRPα conjugates efficiently consume tumor-produced lactates and locally produce tumor-necrotic H 2 O 2 to suppress tumor growth by Kang, Yujin, Yeo, Mirae, Choi, Hyukjun, Jun, Heejin, Eom, Soomin, Park, Seong Guk, Yoon, Haejin, Kim, Eunhee, Kang, Sebyung

“…Aggressive tumor formation often leads to excessive anaerobic glycolysis and massive production and accumulation of lactate in the tumor microenvironment…”
Get full text