Search Results - "Yentur, Sibel P."

Genetic Association of a Gain‐of‐Function IFNGR1 Polymorphism and the Intergenic Region LNCAROD/DKK1 With Behçet’s Disease by Ortiz Fernández, Lourdes, Coit, Patrick, Yilmaz, Vuslat, Yentür, Sibel P., Alibaz‐Oner, Fatma, Aksu, Kenan, Erken, Eren, Düzgün, Nursen, Keser, Gokhan, Cefle, Ayse, Yazici, Ayten, Ergen, Andac, Alpsoy, Erkan, Salvarani, Carlo, Casali, Bruno, Kısacık, Bünyamin, Kötter, Ina, Henes, Jörg, Çınar, Muhammet, Schaefer, Arne, Nohutcu, Rahime M., Zhernakova, Alexandra, Wijmenga, Cisca, Takeuchi, Fujio, Harihara, Shinji, Kaburaki, Toshikatsu, Messedi, Meriam, Song, Yeong‐Wook, Kaşifoğlu, Timuçin, Carmona, F. David, Guthridge, Joel M., James, Judith A., Martin, Javier, González Escribano, María Francisca, Saruhan‐Direskeneli, Güher, Direskeneli, Haner, Sawalha, Amr H.

“…Objective Behçet’s disease is a complex systemic inflammatory vasculitis of incompletely understood etiology. This study was undertaken to investigate genetic…”
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Identification of Multiple Genetic Susceptibility Loci in Takayasu Arteritis by Saruhan-Direskeneli, Güher, Hughes, Travis, Aksu, Kenan, Keser, Gokhan, Coit, Patrick, Aydin, Sibel Z., Alibaz-Oner, Fatma, Kamalı, Sevil, Inanc, Murat, Carette, Simon, Hoffman, Gary S., Akar, Servet, Onen, Fatos, Akkoc, Nurullah, Khalidi, Nader A., Koening, Curry, Karadag, Omer, Kiraz, Sedat, Langford, Carol A., McAlear, Carol A., Ozbalkan, Zeynep, Ates, Askin, Karaaslan, Yasar, Maksimowicz-McKinnon, Kathleen, Monach, Paul A., Ozer, Hüseyin T., Seyahi, Emire, Fresko, Izzet, Cefle, Ayse, Seo, Philip, Warrington, Kenneth J., Ozturk, Mehmet A., Ytterberg, Steven R., Cobankara, Veli, Onat, A. Mesut, Guthridge, Joel M., James, Judith A., Tunc, Ercan, Duzgun, Nurşen, Bıcakcıgil, Muge, Yentür, Sibel P., Merkel, Peter A., Direskeneli, Haner, Sawalha, Amr H.

“…Takayasu arteritis is a rare inflammatory disease of large arteries. The etiology of Takayasu arteritis remains poorly understood, but genetic contribution to…”
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Differential Cytokine Changes in Patients with Myasthenia Gravis with Antibodies against AChR and MuSK by Yilmaz, Vuslat, Oflazer, Piraye, Aysal, Fikret, Durmus, Hacer, Poulas, Kostas, Yentur, Sibel P, Gulsen-Parman, Yesim, Tzartos, Socrates, Marx, Alexander, Tuzun, Erdem, Deymeer, Feza, Saruhan-Direskeneli, Güher

“…Neuromuscular transmission failure in myasthenia gravis (MG) is most commonly elicited by autoantibodies (ab) to the acetylcholine receptor or the…”
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Thymic gene expression analysis reveals a potential link between HIF-1A and Th17/Treg imbalance in thymoma associated myasthenia gravis by Altınönder, İlayda, Kaya, Mustafa, Yentür, Sibel P, Çakar, Arman, Durmuş, Hacer, Yegen, Gülçin, Özkan, Berker, Parman, Yeşim, Sawalha, Amr H, Saruhan-Direskeneli, Guher

“…Myasthenia gravis (MG) is an immune-mediated disease frequently associated with thymic changes. Increased T helper 17 (Th17) cell activity and dysfunctional…”
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CD4 + T Cells of Myasthenia Gravis Patients Are Characterized by Increased IL-21, IL-4, and IL-17A Productions and Higher Presence of PD-1 and ICOS by Çebi, Merve, Durmus, Hacer, Aysal, Fikret, Özkan, Berker, Gül, Gizem Engin, Çakar, Arman, Hocaoglu, Mehmet, Mercan, Metin, Yentür, Sibel P, Tütüncü, Melih, Yayla, Vildan, Akan, Onur, Dogan, Öner, Parman, Yeşim, Saruhan-Direskeneli, Güher

“…Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies predominantly against the acetylcholine receptor (AChR). Specific T cell subsets are…”
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Sex-specific analysis in Behçet's disease reveals higher genetic risk in male patients by Jo, Yun Gun, Fernández, Lourdes Ortiz, Coit, Patrick, Yilmaz, Vuslat, Yentür, Sibel P., Alibaz-Oner, Fatma, Aksu, Kenan, Erken, Eren, Düzgün, Nursen, Keser, Gokhan, Cefle, Ayse, Yazici, Ayten, Ergen, Andac, Alpsoy, Erkan, Salvarani, Carlo, Kısacık, Bünyamin, Kötter, Ina, Henes, Jörg, Çınar, Muhammet, Schaefer, Arne, Nohutcu, Rahime M., Takeuchi, Fujio, Harihara, Shinji, Kaburaki, Toshikatsu, Messedi, Meriam, Song, Yeong-Wook, Kaşifoğlu, Timuçin, Martin, Javier, González Escribano, María Francisca, Saruhan-Direskeneli, Güher, Direskeneli, Haner, Sawalha, Amr H.

“…Behçet's disease tends to be more severe in men than women. This study was undertaken to investigate sex-specific genetic effects in Behçet's disease. A total…”
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Immune alterations in subacute sclerosing panencephalitis reflect an incompetent response to eliminate the measles virus by Yentür, Sibel P, Demirbilek, Veysi, Gurses, Candan, Baris, Safa, Kuru, Umit, Ayta, Semih, Yapici, Zuhal, Adin-Cinar, Suzan, Uysal, Serap, Celik Yilmaz, Gulden, Onal, Emel, Cokar, Ozlem, Saruhan-Direskeneli, Güher

“…In subacute sclerosing panencephalitis (SSPE) the persistence of measles virus (MeV) may be related to the altered immune response. In this study, cytokine…”
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Reduced cerebrospinal fluid levels of interleukin-10 in children with febrile seizures by Şahin, Sevim, Uysal, Serap, Yentür, Sibel P., Kaçar, Alper

“…•Cerebrospinal fluid (CSF) levels of IL-10 were reduced after a febrile seizure (FS).•The levels of IFN-β and IL-12 in CSF did not significantly change with…”
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Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome‐Wide Association Study by Renauer, Paul A., Saruhan‐Direskeneli, Guher, Coit, Patrick, Adler, Adam, Aksu, Kenan, Keser, Gokhan, Alibaz‐Oner, Fatma, Aydin, Sibel Z., Kamali, Sevil, Inanc, Murat, Carette, Simon, Cuthbertson, David, Hoffman, Gary S., Akar, Servet, Onen, Fatos, Akkoc, Nurullah, Khalidi, Nader A., Koening, Curry, Karadag, Omer, Kiraz, Sedat, Langford, Carol A., Maksimowicz‐McKinnon, Kathleen, McAlear, Carol A., Ozbalkan, Zeynep, Ates, Askin, Karaaslan, Yasar, Duzgun, Nursen, Monach, Paul A., Ozer, Huseyin T. E., Erken, Eren, Ozturk, Mehmet A., Yazici, Ayten, Cefle, Ayse, Onat, Ahmet Mesut, Kisacik, Bunyamin, Pagnoux, Christian, Kasifoglu, Timucin, Seyahi, Emire, Fresko, Izzet, Seo, Philip, Sreih, Antoine G., Warrington, Kenneth J., Ytterberg, Steven R., Cobankara, Veli, Cunninghame‐Graham, Deborah S., Vyse, Timothy J., Pamuk, Omer N., Tunc, S. Ercan, Dalkilic, Ediz, Bicakcigil, Muge, Yentur, Sibel P., Wren, Jonathan D., Merkel, Peter A., Direskeneli, Haner, Sawalha, Amr H.

“…Objective Takayasu arteritis is a rare large vessel vasculitis with incompletely understood etiology. This study was undertaken to perform the first unbiased…”
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Genetic heterogeneity within the HLA region in three distinct clinical subgroups of myasthenia gravis by Saruhan-Direskeneli, Güher, Hughes, Travis, Yilmaz, Vuslat, Durmus, Hacer, Adler, Adam, Alahgholi-Hajibehzad, Mahdi, Aysal, Fikret, Yentür, Sibel P, Akalin, Mehmet Ali, Dogan, Oner, Marx, Alexander, Gülsen-Parman, Yesim, Oflazer, Piraye, Deymeer, Feza, Sawalha, Amr H

“…Abstract This study aims to investigate genetic susceptibility to early-onset and late-onset anti-acetylcholine receptor antibody positive myasthenia gravis…”
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Increased costimulatory molecule expression of thymic and peripheral B cells and a sensitivity to IL-21 in myasthenia gravis by Hocaoğlu, Mehmet, Durmuş, Hacer, Özkan, Berker, Yentür, Sibel P., Doğan, Öner, Parman, Yeşim, Deymeer, Feza, Saruhan-Direskeneli, Güher

“…B cells may contribute to the pathogenesis of myasthenia gravis with anti-acetylcholine antibodies (AChR+ MG) by co-stimulation or selection of T cells. In…”
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Granzyme B gene polymorphism associated with subacute sclerosing panencephalitis by Yentur, Sibel P, Aydin, Hatice Nur, Gurses, Candan, Demirbilek, Veysi, Kuru, Umit, Uysal, Serap, Yapici, Zuhal, Baris, Safa, Yilmaz, Gülden, Cokar, Ozlem, Onal, Emel, Gokyigit, Ayşen, Saruhan-Direskeneli, Güher

“…Subacute sclerosing panencephalitis (SSPE) is a late complication of measles infection. Immune dysfunction related to genetic susceptibility has been…”
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A decrease of regulatory T cells and altered expression of NK receptors are observed in subacute sclerosing panencephalitis by Yentur, Sibel P, Gurses, Candan, Demirbilek, Veysi, Adin-Cinar, Suzan, Kuru, Umit, Uysal, Serap, Yapici, Zuhal, Yilmaz, Gülden, Cokar, Ozlem, Onal, Emel, Gökyigit, Aysen, Saruhan-Direskeneli, Güher

“…Subacute sclerosing panencephalitis (SSPE) is caused by a persistent measles virus infection. Regulatory mechanisms can be responsible for a failure of…”
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TIR-domain-containing adaptor protein gene TIRAP S180L polymorphism is not increased in Behçet's disease patients in two ethnic cohorts by Turunc, Gorkem, Coskun, Doga, Alibaz-Oner, Fatma, Coit, Patrick, Duzgun, Nursen, Alpsoy, Erkan, Yentur, Sibel P, Salvarani, Carlo, Casali, Bruno, Kötter, Ina, Ergun, Tulin, Direskeneli, Haner, Sawalha, Amr H, Saruhan-Direskeneli, Guher

“…The single nucleotide polymorphism (SNP) of TIRAP (Serine 180 leucine, S180L) that is shown to be associated with Behçet's disease (BD) in a European-derived…”
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Pro-inflammatory cellular immune response in Behçet's disease by Kulaber, Ayla, Tugal-Tutkun, Ilknur, Yentür, Sibel P, Akman-Demir, Gülşen, Kaneko, Fumio, Gül, Ahmet, Saruhan-Direskeneli, Güher

“…Several proteins are investigated as candidate auto-antigens in the pathogenesis of Behçet's disease (BD). This study aimed to screen the cellular responses to…”
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Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study by Ortiz-Fernández, Lourdes, Saruhan-Direskeneli, Güher, Alibaz-Oner, Fatma, Kaymaz-Tahra, Sema, Coit, Patrick, Kong, Xiufang, Kiprianos, Allan P., Maughan, Robert T., Aydin, Sibel Z., Aksu, Kenan, Keser, Gokhan, Kamali, Sevil, Inanc, Murat, Springer, Jason, Akar, Servet, Onen, Fatos, Akkoc, Nurullah, Khalidi, Nader A., Koening, Curry, Karadag, Omer, Kiraz, Sedat, Forbess, Lindsy, Langford, Carol A., McAlear, Carol A., Ozbalkan, Zeynep, Yavuz, Sule, Çetin, Gozde Yildirim, Alpay-Kanitez, Nilufer, Chung, Sharon, Ates, Askin, Karaaslan, Yasar, McKinnon-Maksimowicz, Kathleen, Monach, Paul A., Ozer, Hüseyin T.E., Seyahi, Emire, Fresko, Izzet, Cefle, Ayse, Seo, Philip, Warrington, Kenneth J., Ozturk, Mehmet A., Ytterberg, Steven R., Cobankara, Veli, Onat, Ahmet Mesut, Duzgun, Nurşen, Bıcakcıgil, Muge, Yentür, Sibel P., Lally, Lindsay, Manfredi, Angelo A., Baldissera, Elena, Erken, Eren, Yazici, Ayten, Kısacık, Bünyamin, Kaşifoğlu, Timuçin, Dalkilic, Ediz, Cuthbertson, David, Pagnoux, Christian, Sreih, Antoine, Reales, Guillermo, Wallace, Chris, Wren, Jonathan D., Cunninghame-Graham, Deborah S., Vyse, Timothy J., Sun, Ying, Chen, Huiyong, Grayson, Peter C., Tombetti, Enrico, Jiang, Lindi, Mason, Justin C., Merkel, Peter A., Direskeneli, Haner, Sawalha, Amr H.

“…Takayasu arteritis is a rare inflammatory disease of large arteries. We performed a genetic study in Takayasu arteritis comprising 6,670 individuals (1,226…”
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Elevated interleukin-12 and CXCL10 in subacute sclerosing panencephalitis by Saruhan-Direskeneli, Güher, Gürses, Candan, Demirbilek, Veysi, Yentür, Sibel P., Yılmaz, Gülden, Önal, Emel, Yapıcı, Zuhal, Yalçınkaya, Cengiz, Çokar, Özlem, Akman-Demir, Gülşen, Gökyiğit, Ayşen

“…Immunosuppression associated with measles virus (MV) can be demonstrated by cytokine production failure in subacute sclerosing panencephalitis (SSPE) and may…”
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IL-12 and IL-10 polymorphisms and their effects on cytokine production by YILMAZ, V, YENTUR, S, SARUHANDIRESKENELI, G

“…Interleukin (IL)-12 is an inducer of differentiation of T helper (Th) cells towards Th1, whereas IL-10 is mainly an anti-inflammatory cytokine inhibiting Th1…”
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Interleukin-6 in neuro-Behçet’s disease: Association with disease subsets and long-term outcome by Akman-Demir, Gülşen, Tüzün, Erdem, İçöz, Sema, Yeşilot, Nilüfer, Yentür, Sibel P., Kürtüncü, Murat, Mutlu, Melike, Saruhan-Direskeneli, Güher

“…Increased cerebrospinal fluid (CSF) IL-6 has been reported in patients with Behçet’s disease (BD) and neurological involvement. To elucidate the value of IL-6…”
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IFN-gamma response against measles virus peptides in subacute sclerosing panencephalitis patients by Yentür, Sibel P, Adin-cinar, Suzan, Gürses, Candan, Demirbilek, Veysi, Baris, Safa, Ayta, Semih, Kuru, Ümit, Yapici, Zuhal, Uysal, Serap, Cokar, Ozlem, Gokyigit, Aysen, Saruhan-direskeneli, Guher

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