Search Results - "Yen, Michael"

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance by Greenbaum, Adam, Hsu, Yen-Michael S., Day, Ryan B., Schuettpelz, Laura G., Christopher, Matthew J., Borgerding, Joshua N., Nagasawa, Takashi, Link, Daniel C.

“…Targeted deletion of the chemokine Cxcl12 in different bone marrow stromal cell populations shows that distinct niches exist in the bone marrow for…”
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Micromolar affinity CAR T cells to ICAM-1 achieves rapid tumor elimination while avoiding systemic toxicity by Park, Spencer, Shevlin, Enda, Vedvyas, Yogindra, Zaman, Marjan, Park, Susan, Hsu, Yen-Michael S., Min, Irene M., Jin, Moonsoo M.

“…Adoptive transfer of high-affinity chimeric antigen receptor (CAR) T cells targeting hematological cancers has yielded impressive clinical results. However,…”
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Office-based Oculoplastic Procedures That Make a Difference by Yen, Michael T

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Extracellular vesicles as cancer liquid biopsies: from discovery, validation, to clinical application by Zhao, Zhen, Fan, Jia, Hsu, Yen-Michael S, Lyon, Christopher J, Ning, Bo, Hu, Tony Y

“…Substantial research has been devoted to elucidate the roles that extracellular vesicles (EVs) play in the regulation of both normal and pathological…”
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Developments in the treatment of benign essential blepharospasm by Yen, Michael T

“…PURPOSE OF REVIEWTo review new developments in the medical and surgical treatment options for benign essential blepharospasm (BEB). RECENT FINDINGSBotulinum…”
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Rapid identification and discrimination of methicillin‐resistant Staphylococcus aureus strains via matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry by Liu, Xin, Su, Taojunfeng, Hsu, Yen‐Michael S., Yu, Hua, Yang, He Sarina, Jiang, Li, Zhao, Zhen

“…Rationale Methicillin‐resistant Staphylococcus aureus (MRSA) is one of major clinical pathogens responsible for both hospital‐ and community‐acquired…”
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CARD9 mediates Dectin-1-induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity by Jia, Xin-Ming, Tang, Bing, Zhu, Le-Le, Liu, Yan-Hui, Zhao, Xue-Qiang, Gorjestani, Sara, Hsu, Yen-Michael S, Yang, Long, Guan, Jian-Hong, Xu, Guo-Tong, Lin, Xin

“…Dectin-1 functions as a pattern recognition receptor for sensing fungal infection. It has been well-established that Dectin-1 induces innate immune responses…”
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The impact of Daratumumab on transfusion service costs by Cushing, Melissa M., DeSimone, Robert A., Goel, Ruchika, Hsu, Yen‐Michael S., Parra, Priscilla, Racine‐Brzostek, Sabrina E., Degtyaryova, Diana, Lo, Dian T., Morrison, Meta, Crowley, Kathleen M., Rossi, Adrianna, Vasovic, Ljiljana V.

“…BACKGROUND Daratumumab (DARA) is a human IgG1κ monoclonal antibody directed against CD38, approved for the treatment of multiple myeloma. As CD38 is expressed…”
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Red blood cells donated by smokers: A pilot investigation of recipient transfusion outcomes by DeSimone, Robert A., Hayden, Joshua A., Mazur, Chase A., Vasovic, Ljiljana V., Sachais, Bruce S., Zhao, Zhen, Goel, Ruchika, Hsu, Yen‐Michael S., Racine‐Brzostek, Sabrina E., Cushing, Melissa M.

“…BACKGROUND Current regulations do not require blood collection facilities to ask donors about cigarette smoking, and the prevalence of nicotine and its…”
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Thawed solvent/detergent‐treated plasma demonstrates comparable clinical efficacy to thawed plasma by Racine‐Brzostek, Sabrina E., Canver, Matthew C., DeSimone, Robert A., Zdravkova, Milena, Lo, Dian T., Crowley, Kathleen M., Hsu, Yen‐Michael S., Vasovic, Ljiljana V., Hill, Shanna Sykes, Cushing, Melissa M.

“…Background Thawed Plasma (TP), plasma thawed and refrigerated for up to 5 days, is a commonly transfused plasma product. This pilot study was conducted to…”
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Residency Research Output of Ophthalmic Plastic and Reconstructive Fellows Amidst the COVID-19 Pandemic by Huang, Austin, Jaber, Jay, Yen, Michael T.

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Differential processing of high‐molecular‐weight kininogen during normal pregnancy by Droll, Stephenie H., Hsu, Yen‐Michael Sheng, Drake, Steven K., Kim, Ashley, Wang, Weixin, Calvo, Katherine R., Cao, Zheng, Hu, Tony Y., Zhao, Zhen

“…Rationale Studies identified kininogen as a potential biomarker of preeclampsia, a major cause of adverse maternal outcomes. High‐molecular‐weight kininogen…”
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Uveal melanoma immunogenomics predict immunotherapy resistance and susceptibility by Leonard-Murali, Shravan, Bhaskarla, Chetana, Yadav, Ghanshyam S., Maurya, Sudeep K., Galiveti, Chenna R., Tobin, Joshua A., Kann, Rachel J., Ashwat, Eishan, Murphy, Patrick S., Chakka, Anish B., Soman, Vishal, Cantalupo, Paul G., Zhuo, Xinming, Vyas, Gopi, Kozak, Dara L., Kelly, Lindsey M., Smith, Ed, Chandran, Uma R., Hsu, Yen-Michael S., Kammula, Udai S.

“…Immune checkpoint inhibition has shown success in treating metastatic cutaneous melanoma but has limited efficacy against metastatic uveal melanoma, a rare…”
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Thyroid Eye Disease: Current Concepts and State of the Art Treatment by Yen, Michael T.

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Manufacturing and preclinical validation of CAR T cells targeting ICAM-1 for advanced thyroid cancer therapy by Vedvyas, Yogindra, McCloskey, Jaclyn E., Yang, Yanping, Min, Irene M., Fahey, Thomas J., Zarnegar, Rasa, Hsu, Yen-Michael S., Hsu, Jing-Mei, Van Besien, Koen, Gaudet, Ian, Law, Ping, Kim, Nak Joon, Hofe, Eric von, Jin, Moonsoo M.

“…While the majority of thyroid cancer patients are easily treatable, those with anaplastic or poorly differentiated recurrent thyroid carcinomas have a very…”
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Differential Use of CARD9 by Dectin-1 in Macrophages and Dendritic Cells by Goodridge, Helen S, Shimada, Takahiro, Wolf, Andrea J, Hsu, Yen-Michael S, Becker, Courtney A, Lin, Xin, Underhill, David M

“…The pattern recognition receptors TLR2 and Dectin-1 play key roles in coordinating the responses of macrophages and dendritic cells (DC) to fungi. Induction of…”
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The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens by Lin, Xin, Hsu, Yen-Michael S, Zhang, Yongliang, You, Yun, Wang, Donghai, Li, Hongxiu, Duramad, Omar, Qin, Xiao-Feng, Dong, Chen

“…The caspase-recruitment domain-containing adaptor protein CARD9 regulates the innate signaling responses to fungal infection. Here we show that CARD9 is…”
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How do I: Evaluate the safety and legitimacy of unproven cellular therapies? by Guleria, Indira, Los Angeles Muñiz, Maria, Wilgo, Matthew, Bapat, Asawari, Cui, Wanxing, Hsu, Yen‐Michael Sheng, Jeyaraman, Madhan, Muthu, Sathish, Rodriguez, Federico, Fesnak, Andrew, Celluzzi, Christina, Sesok‐Pizzini, Deborah, Reich‐Slotky, Ronit, Spitzer, Thomas

“…Background Unproven cellular therapies are being offered to patients for a variety of conditions and diseases for which other treatments have failed. The use…”
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CARD9 Mediates Dectin-2-induced IκBα Kinase Ubiquitination Leading to Activation of NF-κB in Response to Stimulation by the Hyphal Form of Candida albicans by Bi, Liangkuan, Gojestani, Sara, Wu, Weihui, Hsu, Yen-Michael S., Zhu, Jiayuan, Ariizumi, Kiyoshi, Lin, Xin

“…The scaffold protein CARD9 plays an essential role in anti-fungus immunity and is implicated in mediating Dectin-1/Syk-induced NF-κB activation in response to…”
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Therapy With Allogeneic Severe Acute Respiratory Syndrome Coronavirus-2–Specific T Cells for Persistent Coronavirus Disease 2019 in Immunocompromised Patients by Haidar, Ghady, Jacobs, Jana L, Kramer, Kailey Hughes, Naqvi, Asma, Heaps, Amy, Parikh, Urvi, McCormick, Kevin D, Sobolewski, Michele D, Agha, Mounzer, Bogdanovich, Tatiana, Bushunow, Vasilii, Farah, Rafic, Hensley, Matthew, Hsu, Yen-Michael S, Johnson, Bruce, Klamar-Blain, Cynthia, Kozar, Jennifer, Lendermon, Elizabeth, Macatangay, Bernard J C, Marino, Christopher C, Raptis, Anastasios, Salese, Erin, Silveira, Fernanda P, Leen, Ann M, Marshall, William L, Miller, Michael, Patel, Badrish, Atillasoy, Ercem, Mellors, John W

“…Abstract We administered severe acute respiratory syndrome coronavirus-2 viral-specific T cells (VSTs) under emergency investigational new drug applications to…”
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