Search Results - "Yen, B. Linju"

Human mesenchymal stem cells (MSCs) for treatment towards immune- and inflammation-mediated diseases: review of current clinical trials by Wang, Li-Tzu, Ting, Chiao-Hsuan, Yen, Men-Luh, Liu, Ko-Jiunn, Sytwu, Huey-Kang, Wu, Kenneth K, Yen, B Linju

“…Human mesenchymal stem cells (MSCs) are multilineage somatic progenitor/stem cells that have been shown to possess immunomodulatory properties in recent years…”
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Advances in mesenchymal stem cell therapy for immune and inflammatory diseases: Use of cell‐free products and human pluripotent stem cell‐derived mesenchymal stem cells by Wang, Li‐Tzu, Liu, Ko‐Jiunn, Sytwu, Huey‐Kang, Yen, Men‐Luh, Yen, B. Linju

“…Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to be popular based on progressive accumulation of preclinical mechanistic…”
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Induction of immunomodulatory monocytes by human mesenchymal stem cell‐derived hepatocyte growth factor through ERK1/2 by Chen, Pei‐Min, Liu, Ko‐Jiunn, Hsu, Pei‐Ju, Wei, Chung‐Fan, Bai, Chyi‐Huey, Ho, Ling‐Jun, Sytwu, Huey‐Kang, Yen, B. Linju

“…IL‐10‐producing CD14+ immunomodulatory monocytes are induced through human MSC‐secreted HGF via ERK1/2 to modulate allogeneic T cell function. Monocytes are a…”
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Current status of mesenchymal stem cell therapy for immune/inflammatory lung disorders: Gleaning insights for possible use in COVID‐19 by Yen, B. Linju, Yen, Men‐Luh, Wang, Li‐Tzu, Liu, Ko‐Jiunn, Sytwu, Huey‐Kang

“…The broad immunomodulatory properties of human mesenchymal stem cells (MSCs) have allowed for wide application in regenerative medicine as well as…”
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Clinical implications of differential functional capacity between tissue‐specific human mesenchymal stromal/stem cells by Yen, B. Linju, Liu, Ko‐Jiunn, Sytwu, Huey‐Kang, Yen, Men‐Luh

“…Over the past two decades, there has been an explosion in the numbers of clinical trials using mesenchymal stem cells (MSCs). While the safety profile of MSC…”
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Multipotent human mesenchymal stromal cells mediate expansion of myeloid-derived suppressor cells via hepatocyte growth factor/c-met and STAT3 by Yen, B Linju, Yen, Men-Luh, Hsu, Pei-Ju, Liu, Ko-Jiunn, Wang, Chia-Jen, Bai, Chyi-Huey, Sytwu, Huey-Kang

“…Mesenchymal stromal cells (MSCs) are multilineage progenitors with immunomodulatory properties, including expansion of immunomodulatory leukocytes such as…”
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Upregulation of SOX9 in Lung Adenocarcinoma and Its Involvement in the Regulation of Cell Growth and Tumorigenicity by SHIH SHENG JIANG, FANG, Wen-Tsen, LI, Yu-Wei, JANG, Te-Hsuan, CHAN, Shih-Hsuan, SU JING YANG, HSIUNG, Chao A, WU, Cheng-Wen, WANG, Lu-Hai, CHANG, I-Shou, HOU, Ya-Hsiue, HUANG, Shiu-Feng, LINJU YEN, B, CHANG, Junn-Liang, LI, Shih-Miao, LIU, Hui-Ping, LIU, Ying-Lan, HUANG, Chih-Ting

“…SOX9 is an important transcription factor required for development and has been implicated in several types of cancer. However, SOX9 has never been linked to…”
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Correction: Excess glucose alone depress young mesenchymal stromal/stem cell osteogenesis and mitochondria activity within hours/days via NAD + / SIRT1 axis by Yen, B Linju, Wang, Li-Tzu, Wang, Hsiu-Huang, Hung, Chin-Pao, Hsu, Pei-Ju, Chang, Chia-Chi, Liao, Chien-Yu, Sytwu, Huey-Kang, Yen, Men-Luh

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Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells by Chen, Pei-Min, Yen, Men-Luh, Liu, Ko-Jiunn, Sytwu, Huey-Kang, Yen, B-Linju

“…In recent years, a large number of studies have contributed to our understanding of the immunomodulatory mechanisms used by multipotent mesenchymal stem cells…”
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Excess glucose alone depress young mesenchymal stromal/stem cell osteogenesis and mitochondria activity within hours/days via NAD + /SIRT1 axis by Yen, B Linju, Wang, Li-Tzu, Wang, Hsiu-Huang, Hung, Chin-Pao, Hsu, Pei-Ju, Chang, Chia-Chi, Liao, Chien-Yu, Sytwu, Huey-Kang, Yen, Men-Luh

“…The impact of global overconsumption of simple sugars on bone health, which peaks in adolescence/early adulthood and correlates with osteoporosis (OP) and…”
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Neuroprotective Action of Human Wharton’s Jelly-Derived Mesenchymal Stromal Cell Transplants in a Rodent Model of Stroke by Wu, Kuo-Jen, Yu, Seong-Jin, Chiang, Chia-Wen, Lee, Yu-Wei, Yen, B Linju, Tseng, Pei-Chi, Hsu, Chun-Sen, Kuo, Li-Wei, Wang, Yun

“…Wharton’s jelly-derived mesenchymal stromal cells (WJ-MSCs) have distinct immunomodulatory and protective effects against kidney, liver, or heart injury…”
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Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses by Wang, Wei-Bei, Yen, Men-Luh, Liu, Ko-Jiunn, Hsu, Pei-Ju, Lin, Ming-Hong, Chen, Pei-Min, Sudhir, Putty-Reddy, Chen, Chein-Hung, Chen, Chung-Hsuan, Sytwu, Huei-Kang, Yen, B. Linju

“…Multipotent human mesenchymal stromal cells (hMSCs) harbor immunomodulatory properties that are therapeutically relevant. One of the most clinically important…”
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Physiological concentrations of soluble uric acid are chondroprotective and anti-inflammatory by Lai, Jenn-Haung, Luo, Shue-Fen, Hung, Li-Feng, Huang, Chuan-Yueh, Lien, Shiu-Bii, Lin, Leou-Chyr, Liu, Feng-Cheng, Yen, B. Linju, Ho, Ling-Jun

“…High uric acid levels are a risk factor for cardiovascular disorders and gout; however, the role of physiological concentrations of soluble uric acid (sUA) is…”
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HLA-G Expression in Human Mesenchymal Stem Cells (MSCs) Is Related to Unique Methylation Pattern in the Proximal Promoter as well as Gene Body DNA by Yen, B Linju, Hwa, Hsiao-Lin, Hsu, Pei-Ju, Chen, Pei-Min, Wang, Li-Tzu, Jiang, Shih-Sheng, Liu, Ko-Jiunn, Sytwu, Huey-Kang, Yen, Men-Luh

“…Multipotent human mesenchymal stem cells (MSCs) harbor clinically relevant immunomodulation, and HLA-G, a non-classical MHC class I molecule with highly…”
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Stromal Galectin-1 Promotes Colorectal Cancer Cancer-Initiating Cell Features and Disease Dissemination Through SOX9 and β-Catenin: Development of Niche-Based Biomarkers by Peng, Kai-Yen, Jiang, Shih-Sheng, Lee, Yu-Wei, Tsai, Fang-Yu, Chang, Chia-Chi, Chen, Li-Tzong, Yen, B. Linju

“…Over 90% of colorectal cancer (CRC) patients have mutations in the Wnt/β-catenin pathway, making the development of biomarkers difficult based on this critical…”
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Protocol for efficient human MSC chondrogenesis via Wnt antagonism instead of TGF-β by Hsieh, Chen-Chan, Chang, Chia-Chi, Hsu, Pei-Ju, Chen, Linyi, Yen, B. Linju

“…To better implement mesenchymal stem cell (MSC)-based therapy toward cartilage diseases, a more efficient and less off-target chondrogenesis protocol is…”
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Isolation of Multipotent Cells from Human Term Placenta by Yen, B. Linju, Huang, Hsing‐I, Chien, Chih‐Cheng, Jui, Hsiang‐Yiang, Ko, Bor‐Sheng, Yao, Ming, Shun, Chia‐Tung, Yen, Men‐luh, Lee, Meng‐Chou, Chen, Yao‐Chang

“…Current sources of stem cells include embryonic stem cells (ESCs) and adult stem cells (ASCs). However, concerns exist with either source: ESCs, with their…”
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Resident vs nonresident multipotent mesenchymal stromal cell interactions with B lymphocytes result in disparate outcomes by Lee, Wei, Wang, Li‐Tzu, Yen, Men‐Luh, Hsu, Pei‐Ju, Lee, Yu‐Wei, Liu, Ko‐Jiunn, Lin, Kuo‐I, Su, Yu‐Wen, Sytwu, Huey‐Kang, Yen, B. Linju

“…Multipotent human mesenchymal stromal cells (MSCs) from multiple organs including the bone marrow (BM) and placenta harbor clinically relevant immunomodulation…”
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Solid freeform-fabricated scaffolds designed to carry multicellular mesenchymal stem cell spheroids for cartilage regeneration by Huang, G S, Tseng, C S, Linju Yen, B, Dai, L G, Hsieh, P S, Hsu, S-h

“…Three-dimensional (3D) cellular spheroids have recently emerged as a new trend to replace suspended single cells in modern cell-based therapies because of…”
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Transplantation of human placenta-derived multipotent stem cells reduces ischemic brain injury in adult rats by Wu, Kou-Jen, Yu, Seong-Jin, Chiang, Chia-Wen, Cho, Kuna-Hung, Lee, Yu-Wei, Yen, B Linju, Kuo, Li-Wei, Wang, Yun

“…After the onset of stroke, a series of progressive and degenerative reactions, including inflammation, is activated, which leads to cell death. We recently…”
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