Search Results - "Yeldell, Sean B."

Transcriptome in vivo analysis (TIVA) of spatially defined single cells in live tissue by Lovatt, Ditte, Ruble, Brittani K, Lee, Jaehee, Dueck, Hannah, Kim, Tae Kyung, Fisher, Stephen, Francis, Chantal, Spaethling, Jennifer M, Wolf, John A, Grady, M Sean, Ulyanova, Alexandra V, Yeldell, Sean B, Griepenburg, Julianne C, Buckley, Peter T, Kim, Junhyong, Sul, Jai-Yoon, Dmochowski, Ivan J, Eberwine, James

“…A noninvasive method is reported for the isolation and profiling of the transcriptome from a single cell in the context of intact tissue. Transcriptome…”
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Efficient Synthesis of Light‐Triggered Circular Antisense Oligonucleotides Targeting Cellular Protein Expression by Yang, Linlin, Kim, Hyun Bum, Sul, Jai‐Yoon, Yeldell, Sean B., Eberwine, James H., Dmochowski, Ivan J.

“…Light‐activated (“caged”) antisense oligonucleotides are powerful molecules for regulating gene expression at submicron spatial resolution through the focal…”
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Nucleic acid constructs for the interrogation of multivalent protein interactions by Yeldell, Sean B, Seitz, Oliver

“…Multivalency is nature's way to establish firm and specific interactions when the binding sites of a protein receptor have only low affinity for monovalent…”
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Caged oligonucleotides for studying biological systems by Ruble, Brittani K., Yeldell, Sean B., Dmochowski, Ivan J.

“…Light-activated (“caged”) compounds have been widely employed for studying biological processes with high spatial and temporal control. In the past decade,…”
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Oligonucleotide Probe for Transcriptome in Vivo Analysis (TIVA) of Single Neurons with Minimal Background by Yeldell, Sean B., Yang, Linlin, Lee, Jaehee, Eberwine, James H., Dmochowski, Ivan J.

“…Messenger RNA (mRNA) isolated from single cells can generate powerful biological insights, including the discovery of new cell types with unique functions as…”
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In situ analysis and imaging of aromatic amidine at varying ligand densities in solid phase by Ortiz-Hernandez, Christian J., Santiago-Ruiz, Adriana N., Torres-Rosado, Adaliz J., Jiménez-Gonzalez, Jomarie, Yeldell, Sean B., Oyola, Rolando, Dmochowski, Ivan J., Sotero-Esteva, Jose, Bansal, Vibha, Fasoli, Ezio

“…We report the development of a fast and accurate fluorescence-based assay for amidine linked to cellulose membranes and Sepharose gel. The assay is founded on…”
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In situ analysis and imaging of aromatic amidine at varying ligand density in solid phase by Ortiz-Hernandez, Christian J, Santiago-Ruiz, Adriana N, Torres-Rosado, Adaliz J, Jiménez-Gonzalez, Jomarie, Yeldell, Sean B, Oyola, Rolando, Dmochowski, Ivan J, Sotero-Esteva, Jose, Bansal, Vibha, Fasoli, Ezio

“…We report the development of a fast and accurate fluorescence-based assay for amidine linked to cellulose membranes and Sepharose gel. The assay is founded on…”
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Next-Generation Oligonucleotide Probes for Transcriptome in Vivo Analysis (TIVA) by Yeldell, Sean B

“…The transcriptome – the total collection of every RNA transcript in a cell – provides a unique readout of a cell’s commands as it executes its own genetic…”
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Transcriptome In Vivo Analysis (TIVA) of spatially defined single cells in intact live mouse and human brain tissue by Lovatt, Ditte, Ruble, Brittani K., Lee, Jaehee, Dueck, Hannah, Kim, Tae Kyung, Fisher, Stephen, Francis, Chantal, Spaethling, Jennifer M., Wolf, John A., Grady, M. Sean, Ulyanova, Alexandra V., Yeldell, Sean B., Griepenburg, Julianne C., Buckley, Peter T., Kim, Junhyong, Sul, Jai-Yoon, Dmochowski, Ivan J., Eberwine, James

“…Transcriptome profiling is an indispensable tool in advancing the understanding of single cell biology, but depends upon methods capable of isolating mRNA at…”
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