Search Results - "Yeh, Che‐Chung"

N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes by Joffre, Jérémie, Wong, Erika, Lawton, Samira, Lloyd, Elliot, Nguyen, Nina, Xu, Fengyun, Sempio, Cristina, Kobzik, Lester, Zlatanova, Ivana, Schumacher, Mark, Klawitter, Jost, Su, Hua, Rabl, Katalin, Wilhelmsen, Kevin, Yeh, Che-Chung, Hellman, Judith

“…The transient receptor potential vanilloid 1 (TRPV1) participates in thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain…”
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Role of CD44 in increasing the potency of mesenchymal stem cell extracellular vesicles by hyaluronic acid in severe pneumonia by Zhou, Li, Hao, Qi, Sugita, Shinji, Naito, Yoshifumi, He, Hongli, Yeh, Che-Chung, Lee, Jae-Woo

“…Although promising, clinical translation of human mesenchymal stem or stromal cell-derived extracellular vesicles (MSC EV) for acute lung injury is potentially…”
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Inhibition of yes‐associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model by Hsu, Ping‐Chih, Miao, Jinbai, Huang, Zhen, Yang, Yi‐Lin, Xu, Zhidong, You, Joanna, Dai, Yuyuan, Yeh, Che‐Chung, Chan, Geraldine, Liu, Shu, Urisman, Anatoly, Yang, Cheng‐Ta, Jablons, David M., You, Liang

“…Yes‐associated protein (YAP) is a main mediator of the Hippo pathway and promotes cancer development and progression in human lung cancer. We sought to…”
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Shift toward greater pathologic post-myocardial infarction remodeling with loss of the adaptive hypertrophic signaling of alpha1 adrenergic receptors in mice by Yeh, Che-Chung, Fan, Yanying, Xu, Yanchun, Yang, Yi-Lin, Simpson, Paul C, Mann, Michael J

“…We have hypothesized that post-infarction cardiac remodeling can be influenced by shifts in the balance between intracellular mediators of "pathologic" and…”
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Spacial and Temporal Patterns of Gene Expression After Cardiac MEK1 Gene Transfer Improve Post‐Infarction Remodeling Without Inducing Global Hypertrophy by Fan, Yanying, Yang, Yi‐Lin, Yeh, Che‐Chung, Mann, Michael J.

“…ABSTRACT Alteration of mitogen activated protein (MAP) kinase signaling in transgenic mice can ameliorate post‐myocardial infarction (MI) remodeling. However,…”
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Biomimetic matrices for myocardial stabilization and stem cell transplantation by Wall, Samuel T., Yeh, Che-Chung, Tu, Richard Y. K., Mann, Michael J., Healy, Kevin E.

“…Although natural biological matrices have demonstrated modest improvement in the survival of cells transplanted into the infarcted myocardium, these materials…”
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Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect by Yeh, Che-Chung, Fan, Yanying, Yang, Yi-Lin, Mann, Michael J

“…MEK1 mutation and activated MAPK signaling has been found in patients with RASopathies and abnormal cardiac development. Previous studies have suggested that…”
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Lung tumourigenesis in a conditional Cul4A transgenic mouse model by Yang, Yi-Lin, Hung, Ming-Szu, Wang, Yang, Ni, Jian, Mao, Jian-Hua, Hsieh, David, Au, Alfred, Kumar, Atul, Quigley, David, Fang, Li Tai, Yeh, Che-Chung, Xu, Zhidong, Jablons, David M, You, Liang

“…Cullin4A (Cul4A) is a scaffold protein that assembles cullin–RING ubiquitin ligase (E3) complexes and regulates many cellular events, including cell survival,…”
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Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse by Yeh, Che-Chung, Li, Hongzhe, Malhotra, Deepak, Turcato, Sally, Nicholas, Susan, Tu, Richard, Zhu, Bo-Qing, Cha, John, Swigart, Philip M, Myagmar, Bat-Erdene, Baker, Anthony J., Simpson, Paul C., Mann, Michael J.

“…Global activation of MAP kinases has been reported in both human and experimental heart failure. Chronic remodeling of the surviving ventricular wall after…”
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MEK1-induced physiological hypertrophy inhibits chronic post-myocardial infarction remodeling in mice by Yeh, Che-Chung, Malhotra, Deepak, Yang, Yi-Lin, Xu, Yanchun, Fan, Yanying, Li, Hongzhe, Mann, Michael J.

“…Although activation of MEK‐ERK signaling is known to be cardioprotective during acute reperfusion injury, the effect of MEK activation on chronic changes in…”
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Sphingolipid signaling and treatment during remodeling of the uninfarcted ventricular wall after myocardial infarction by Yeh, Che-Chung, Li, Hongzhe, Malhotra, Deepak, Huang, Mei-Chuan, Zhu, Bo-Qing, Goetzl, Edward J, Vessey, Donald A, Karliner, Joel S, Mann, Michael J

“…The sphingosine kinase (SphK)/sphingosine 1-phosphate (S1P) pathway, known to determine the fate and growth of various cell types, can enhance cardiac myocyte…”
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Activation of CB1R Promotes Lipopolysaccharide-Induced IL-10 Secretion by Monocytic Myeloid-Derived Suppressive Cells and Reduces Acute Inflammation and Organ Injury by Joffre, Jérémie, Yeh, Che-Chung, Wong, Erika, Thete, Mayuri, Xu, Fengyun, Zlatanova, Ivana, Lloyd, Elliot, Kobzik, Lester, Legrand, Matthieu, Hellman, Judith

“…Abstract Cannabis sativa and its principal components, Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol, are increasingly being used to treat a variety of…”
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Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease by Mahimkar, Rajeev, Nguyen, Anita, Mann, Michael, Yeh, Che-Chung, Zhu, Bo-Qing, Karliner, Joel S, Lovett, David H

“…Abstract Introduction Myxomatous mitral valve “degeneration” with prolapse (MVP) is the most frequent form of nonischemic mitral valve disease. In myxomatous…”
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Induction of protein growth factor systems in the ovaries of transgenic mice overexpressing human type 2 lysophosphatidic acid G protein-coupled receptor (LPA ) by HUANG, Mei-Chuan, LEE, Hsin-Yu, YEH, Che-Chung, KONG, Yvonne, ZALOUDEK, Charles J, GOETZL, Edward J

“…The lipid growth factor lysophosphatidic acid (LPA) is produced by ovarian cancer cells in quantities sufficient to attain concentrations of up to 10 microM…”
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Oxidative stress and antioxidant status in mouse liver: effects of dietary lipid, vitamin E and iron by Ibrahim, W, Lee, U S, Yeh, C C, Szabo, J, Bruckner, G, Chow, C K

“…The purpose of this study was to determine the effects of dietary fat, vitamin E and iron on oxidative damage and antioxidant status. Male Swiss-Webster mice…”
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Surgical ventricular reconstruction in mice: Elucidating potential targets for combined molecular/surgical intervention by Yeh, Che-Chung, PhD, Malhotra, Deepak, MD, Li, Hongzhe, MD, PhD, Nicholas, Susan, MD, Tu, Richard, MD, Mann, Michael J., MD

“…Objectives We hypothesize that persistent alterations in molecular signaling may drive recurrent pathologic remodeling even after the reduction of mechanical…”
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Myocardial Survival Signaling in Response to Stem Cell Transplantation by Li, Hongzhe, MD, PhD, Malhotra, Deepak, MD, Yeh, Che-chung, MD, Tu, Richard, MD, Zhu, Bo-Qing, MD, Birger, Noy, BA, Wisneski, Andrew, Cha, John, BS, Karliner, Joel S., MD, Mann, Michael J., MD, FACS

“…Background Experimental human stem cell transplantation to the heart has begun, but the mechanisms underlying benefits seen in preclinical models, both at the…”
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Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells by YONG XU, KRISHNAN, A, WAN, X. S, MAJIMA, H, YEH, C.-C, LUDEWIG, G, KASARSKIS, E. J, STCLAIR, D. K

“…Manganese superoxide dismutase (MnSOD) has been shown to play an important role in preventing the development of cancer. MnSOD activity is reduced in many…”
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Genistein Suppresses Growth of Human Uterine Sarcoma Cell Lines via Multiple Mechanisms by Yeh, Che-Chung, Fan, Yanying, Jiang, Long, Yang, Yi-Lin, He, Biao, You, Liang, Mann, Michael

“…The estrogen-like soy isoflavone genistein can suppress the growth of a number of different types of cancer cells, but its effect on uterine sarcoma is…”
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Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma by Jiang, Long, Tolani, Bhairavi, Yeh, Che-Chung, Fan, Yanying, Reza, Joseph A, Horvai, Andrew E, Xia, Endi, Kratz, Johannes R, Jablons, David M, Mann, Michael J

“…Despite numerous discoveries regarding the molecular genesis and progression of primary cancers, the biology of metastasis remains poorly understood. Compared…”
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