Search Results - "Yegen, Berrak C."

Anti‐inflammatory Effect of Obestatin and Ghrelin in Dextran Sulfate Sodium–Induced Colitis in Rats by Pamukcu, Ozge, Kumral, Zarife Nigar Ozdemir, Ercan, Feriha, Yegen, Berrak Ç., Ertem, Deniz

“…ABSTRACT Background and Objectives: Obestatin and ghrelin are hormones derived from the same gene but have opposing effects. Ghrelin has anti‐inflammatory…”
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The Novel Function of Nesfatin-1 as an Anti-inflammatory and Antiapoptotic Peptide in Subarachnoid Hemorrhage–Induced Oxidative Brain Damage in Rats by Özsavcí, Derya, Erşahin, Mehmet, Şener, Azize, Özakpinar, Özlem Bingol, Toklu, Hale Z., Akakín, Dilek, Şener, Göksel, Yeğen, Berrak Ç

“…Abstract BACKGROUND: There is substantial evidence to suggest that oxidative stress plays a significant role in the development of acute brain injury after…”
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β-glucan ameliorates methotrexate-induced oxidative organ injury via its antioxidant and immunomodulatory effects by Şener, Göksel, Ekşioğlu-Demiralp, Emel, Çetiner, Mustafa, Ercan, Feriha, Yeğen, Berrak Ç.

“…Methotrexate is an antifolate that is widely used in the treatment of rheumatic disorders and malignant tumors. The efficacy of methotrexate is often limited…”
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Anti-Inflammatory, Antioxidant and Neuroprotective Effects of Niacin on Mild Traumatic Brain Injury in Rats by Ozaydin, Dilan, Kuru Bektasoglu, Pinar, Koyuncuoglu, Turkan, Colakoglu Ozkaya, Seyma, Karagoz Koroglu, Ayca, Akakin, Dilek, Erzik, Can, Yüksel, Meral, Ç Yegen, Berrak, Gurer, Bora

“…Niacin is a water-soluble vitamin. The effects of niacin on inflammation, oxidative stress and apoptotic processes observed after mild traumatic brain injury…”
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Activation of the Alpha 7 Nicotinic Acetylcholine Receptor by GTS-21 Mitigates Contrast Nephropathy in a Rat Model by Akcay, Seckin, Ozdemir Kumral, Zarife Nigar, Cilingir-Kaya, Ozlem Tugce, Peker Eyüboglu, Irem, Akkiprik, Mustafa, Yegen, Berrak C, Koc, Mehmet

“…Contrast nephropathy (CN) is characterized by oxidative stress, vasoconstriction, tubular toxicity, and hypoxia of the renal medulla. We aimed to test the…”
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Pulmonary delivery of favipiravir inhalation solution for COVID-19 treatment: in vitro characterization, stability, in vitro cytotoxicity, and antiviral activity using real time cell analysis by Yildiz Pekoz, Ayca, Akbal Dagistan, Ozlem, Fael, Hanan, Culha, Meltem, Erturk, Aybige, Basarir, Nur Sena, Sahin, Gokben, Serhatli, Muge, Cakirca, Gamze, Tekin, Saban, Sen, Leyla Semiha, Sevim, Mustafa, Mulazimoglu Durmusoglu, Lutfiye, Yegen, Berrak C.

“…Favipiravir, an RNA-dependent RNA polymerase (RdRp) inhibitor, is used to treat patients infected with influenza virus and most recently with SARS-CoV-2…”
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The protective effect of oxytocin on renal ischemia/reperfusion injury in rats by Tuğtepe, Halil, Şener, Göksel, Bıyıklı, Neşe Karaaslan, Yüksel, Meral, Çetinel, Şule, Gedik, Nursal, Yeğen, Berrak Ç.

“…Oxytocin was previously shown to have anti-inflammatory effects in different inflammation models. The major objective of the present study was to evaluate the…”
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Taurine protects against methotrexate-induced toxicity and inhibits leukocyte death by Çetiner, Mustafa, Şener, Göksel, Şehirli, A. Özer, Ekşioğlu-Demiralp, Emel, Ercan, Feriha, Şirvancı, Serap, Gedik, Nursal, Akpulat, Sertaç, Tecimer, Tülay, Yeğen, Berrak Ç.

“…The efficacy of methotrexate (MTX), a widely used cytotoxic chemotherapeutic agent, is often limited by severe side effects and toxic sequelae. Regarding the…”
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Melatonin reduces experimental subarachnoid hemorrhage-induced oxidative brain damage and neurological symptoms by Ersahin, Mehmet, Toklu, Hale Z., Çetinel, Şule, Yüksel, Meral, Yeğen, Berrak Ç., Şener, Göksel

“…:  Oxidative stress has detrimental effects in several models of neurodegenerative diseases, including subarachnoid hemorrhage (SAH). This study investigated…”
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Melatonin treatment protects against spinal cord injury induced functional and biochemical changes in rat urinary bladder by Erşahin, Mehmet, Özdemir, Zarife, Özsavcı, Derya, Akakın, Dilek, Yeğen, Berrak Ç., Reiter, Russel J., Şener, Göksel

“…:  Oxidative stress induced by spinal cord injury (SCI) has deleterious effects on the function of several organ systems including the urinary bladder. In this…”
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Ghrelin alleviates biliary obstruction-induced chronic hepatic injury in rats by ISERI, Sevgin Ozlem, SENER, Göksel, SAGLAM, Beyhan, ERCAN, Feriha, GEDIK, Nursal, YEGEN, Berrak C

“…Reactive oxygen species and oxidative stress are implicated in hepatic stellate cell activation and liver fibrosis, which are initiated by recruitment of…”
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Oxytocin ameliorates skin damage and oxidant gastric injury in rats with thermal trauma by İşeri, Sevgin Özlem, Gedik, İsmail Ertuğrul, Erzik, Can, Uslu, Bahar, Arbak, Serap, Gedik, Nursal, Yeğen, Berrak Ç

“…Abstract Transient splanchnic vasoconstriction following major burns causes oxidative and/or nitrosative damage in gastrointestinal tissues due to ischemia,…”
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Pulmonary Delivery of Favipiravir in Rats Reaches High Local Concentrations without Causing Oxidative Lung Injury or Systemic Side Effects by Akbal-Dagistan, Ozlem, Sevim, Mustafa, Sen, Leyla Semiha, Basarir, Nur Sena, Culha, Meltem, Erturk, Aybige, Fael, Hanan, Kaptan, Engin, Sancar, Serap, Mulazimoglu Durmusoglu, Lutfiye, Yegen, Berrak C, Yildiz-Pekoz, Ayca

“…Favipiravir displays a rapid viral clearance, a high recovery rate and broad therapeutic safety; however, its oral administration was associated with systemic…”
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Oxytocin alleviates hepatic ischemia–reperfusion injury in rats by Düşünceli, Fikret, İşeri, Sevgin Ö., Ercan, Feriha, Gedik, Nursal, Yeğen, Cumhur, Yeğen, Berrak Ç.

“…Various mechanisms have been proposed for the pathogenesis of postischemic hepatic injury, including the generation of reactive oxygen metabolites. Oxytocin…”
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Melatonin improves cardiovascular function and ameliorates renal, cardiac and cerebral damage in rats with renovascular hypertension by Erşahin, Mehmet, Şehirli, Özer, Toklu, Hale Z., Süleymanoglu, Selami, Emekli-Alturfan, Ebru, Yarat, Ayşen, Tatlıdede, Elif, Yeğen, Berrak Ç., Şener, Göksel

“…:  The effect of melatonin was investigated in an angiotensin II‐dependent renovascular hypertension model in Wistar albino rats by placing a renal artery clip…”
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Oxytocin alleviates oxidative renal injury in pyelonephritic rats via a neutrophil-dependent mechanism by Bıyıklı, Neşe Karaaslan, Tuğtepe, Halil, Şener, Göksel, Velioğlu-Öğünç, Ayliz, Çetinel, Şule, Midillioğlu, Şükrü, Gedik, Nursal, Yeğen, Berrak Ç.

“…Background: Urinary tract infection (UTI) may cause inflammation of the renal parenchyma and may lead to impairment in renal function and scar formation…”
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Oxytocin or Social Housing Alleviates Local Burn Injury in Rats by İşeri, Sevgin Özlem, M.D, Düşünceli, Fikret, M.D, Erzik, Can, M.D, Uslu, Bahar, M.D, Arbak, Serap, Ph.D, Yeğen, Berrak Ç., M.D

“…Background Thermal injury may cause distant organ inflammation and multiorgan failure. Oxytocin (OT), a nonapeptide, modulates the immune and inflammatory…”
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Melatonin prevents methotrexate-induced hepatorenal oxidative injury in rats by Jahovic, Nermina, Çevik, Hülya, Şehirli, A. Özer, Yeğen, Berrak Ç., Şener, Göksel

“…:  Regarding the mechanisms of methotrexate (MTX) hepatotoxicity and nephrotoxicity, several hypotheses have been put forward, among which oxidative stress…”
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Role of garlic in the prevention of ischemia-reperfusion injury by Sener, Göksel, Sakarcan, Abdullah, Yeǧen, Berrak Ç.

“…Garlic in different forms has antioxidant properties. These properties are shown to be due to the existence of compounds such as water soluble organosulfur…”
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Oxytocin treatment alleviates stress-aggravated colitis by a receptor-dependent mechanism by CETINEL, Sule, HANCIOGLU, Sertan, SENER, Emre, ÜNER, Can, KILIC, Merve, SENER, Göksel, YEGEN, Berrak C

“…The potential protective effect of OT on a stress-aggravated colitis model in rats and the involvement of OT receptors were evaluated. Holeboard test…”
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