Search Results - "Yee, Leow Chiuan"

Global Prevalence of Nosocomial Multidrug-Resistant Klebsiella pneumoniae : A Systematic Review and Meta-Analysis by Mohd Asri, Nur Ain, Ahmad, Suhana, Mohamud, Rohimah, Mohd Hanafi, Nurmardhiah, Mohd Zaidi, Nur Fatihah, Irekeola, Ahmad Adebayo, Shueb, Rafidah Hanim, Yee, Leow Chiuan, Mohd Noor, Norhayati, Mustafa, Fatin Hamimi, Yean, Chan Yean, Yusof, Nik Yusnoraini

“…The emergence of nosocomial multidrug-resistant is an escalating public health threat worldwide. The prevalence of nosocomial infections due to was recorded up…”
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Advances of Reverse Vaccinology for mRNA Vaccine Design against SARS-CoV-2: A Review of Methods and Tools by da Silva, Maria Karolaynne, Campos, Daniel Melo de Oliveira, Akash, Shopnil, Akter, Shahina, Yee, Leow Chiuan, Fulco, Umberto Laino, Oliveira, Jonas Ivan Nobre

“…mRNA vaccines are a new class of vaccine that can induce potent and specific immune responses against various pathogens. However, the design of mRNA vaccines…”
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Isolation and characterization of malaria PfHRP2 specific VNAR antibody fragments from immunized shark phage display library by Leow, Chiuan Herng, Fischer, Katja, Leow, Chiuan Yee, Braet, Katleen, Cheng, Qin, McCarthy, James

“…Background Malaria rapid diagnostic tests (RDTs) represent an important antibody based immunoassay platform. Unfortunately, conventional monoclonal antibodies…”
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Shigella iron-binding proteins: An insight into molecular physiology, pathogenesis, and potential target vaccine development by Hisyam Bin Ismail, Che Muhammad Khairul, Raihan Mohammad Shabani, Nor, Chuah, Candy, Hassan, Zurina, Bakar Abdul Majeed, Abu, Herng Leow, Chiuan, Kaur Banga Singh, Kirnpal, Yee Leow, Chiuan

“…•Iron is an essential supplement in most living organisms including the survival of the pathogens during pathogenesis.•Shigella strains have evolved a variety…”
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Malaria drives T cells to exhaustion by Wykes, Michelle N, Horne-Debets, Joshua M, Leow, Chiuan-Yee, Karunarathne, Deshapriya S

“…Malaria is a significant global burden but after >30 years of effort there is no vaccine on the market. While the complex life cycle of the parasite presents…”
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The role of REST and HDAC2 in epigenetic dysregulation of Nav1.5 and nNav1.5 expression in breast cancer by Kamarulzaman, Nur Sabrina, Dewadas, Hemaniswarri Dewi, Leow, Chiuan Yee, Yaacob, Nik Soriani, Mokhtar, Noor Fatmawati

“…Increased expression of voltage-gated sodium channels (VGSCs) have been implicated with strong metastatic potential of human breast cancer in vitro and in vivo…”
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Innate and Adaptive Immunity during SARS-CoV-2 Infection: Biomolecular Cellular Markers and Mechanisms by Brown, Brent, Ojha, Vanshika, Fricke, Ingo, Al-Sheboul, Suhaila A, Imarogbe, Chinua, Gravier, Tanya, Green, Michael, Peterson, Lori, Koutsaroff, Ivoyl P, Demir, Ayça, Andrieu, Jonatane, Leow, Chiuan Yee, Leow, Chiuan Herng

“…The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2…”
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Insights into structural vaccinology harnessed for universal coronavirus vaccine development by Lim, Chin Peng, Leow, Chiuan Herng, Lim, Hui Ting, Kok, Boon Hui, Chuah, Candy, Oliveira, Jonas Ivan Nobre, Jones, Malcolm, Leow, Chiuan Yee

“…Structural vaccinology is pivotal in expediting vaccine design through high-throughput screening of immunogenic antigens. Leveraging the structural and…”
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Immunopathogenesis of Nipah Virus Infection and Associated Immune Responses by Brown, Brent, Gravier, Tanya, Fricke, Ingo, Al-Sheboul, Suhaila A., Carp, Theodor-Nicolae, Leow, Chiuan Yee, Imarogbe, Chinua, Arabpour, Javad

“…Pandemics in the last two centuries have been initiated by causal pathogens that include Severe Acute Coronavirus 2 (SARS-CoV-2) and Influenza (e.g., the H1N1…”
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Reverse vaccinology approach for the identification and characterization of outer membrane proteins of Shigella flexneri as potential cellular- and antibody-dependent vaccine candidates by Leow, Chiuan Yee, Kazi, Ada, Hisyam Ismail, Che Muhammad Khairul, Chuah, Candy, Lim, Boon Huat, Leow, Chiuan Herng, Banga Singh, Kirnpal Kaur

“…In the developing world, bacillary dysentery is one of the most common communicable diarrheal infections. There are approximately 169 million cases of…”
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Single Domain Antibodies as New Biomarker Detectors by Leow, Chiuan Herng, Fischer, Katja, Leow, Chiuan Yee, Cheng, Qin, Chuah, Candy, McCarthy, James

“…Biomarkers are defined as indicators of biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention. Biomarkers have…”
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Identification of MHC Class II Immunopeptidomes from Shigella flexneri 2a-infected Macrophages as Potential Vaccine Candidates by Shabani, Nor Raihan Mohammad, Ismail, Che Muhammad Khairul Hisyam, Leow, Chiuan Herng, Mokhtar, Munirah, Singh, Kirnpal Kaur Banga, Leow, Chiuan Yee

“…BACKGROUND: Shigella is a Gram-negative rod-shaped intracellular bacterial pathogen that causes bacterial dysentery or shigellosis among children under five…”
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Dengue virus infection – a review of pathogenesis, vaccines, diagnosis and therapy by Kok, Boon Hui, Lim, Hui Ting, Lim, Chin Peng, Lai, Ngit Shin, Leow, Chiuan Yee, Leow, Chiuan Herng

“…•Reviews on unsolved issues of DENV from different perspectives such as the effect of antibody dependent enhancement, immune escape and limitations of…”
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Flavivirus infection—A review of immunopathogenesis, immunological response, and immunodiagnosis by Chong, Hui Ying, Leow, Chiuan Yee, Abdul Majeed, Abu Bakar, Leow, Chiuan Herng

“…Flaviviruses are group of single stranded RNA viruses that cause severe endemic infection and epidemics on a global scale. It presents a significant health…”
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Current progress of immunoinformatics approach harnessed for cellular- and antibody-dependent vaccine design by Kazi, Ada, Chuah, Candy, Majeed, Abu Bakar Abdul, Leow, Chiuan Herng, Lim, Boon Huat, Leow, Chiuan Yee

“…Immunoinformatics plays a pivotal role in vaccine design, immunodiagnostic development, and antibody production. In the past, antibody design and vaccine…”
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Generation of soluble, disulfide-rich JEV NS1 protein recognizable by anti-NS1 antibodies through a simplified, in vitro refolding approach by Chong, Hui Ying, Leow, Chiuan Yee, Leow, Chiuan Herng

“…Co-existence of Japanese Encephalitis virus (JEV) with highly homologous antigenic epitopes results in antibody-based serodiagnosis being inaccurate at…”
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Diagnostic and therapeutic potential of shark variable new antigen receptor (VNAR) single domain antibody by Cheong, Wei Shien, Leow, Chiuan Yee, Abdul Majeed, Abu Bakar, Leow, Chiuan Herng

“…Conventional monoclonal antibodies (mAbs) have been widely used in research and diagnostic applications due to their high affinity and specificity. However,…”
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Development of an immunoaffinity chromatographic adsorbent using a moderate affinity, anti-salbutamol chicken scFv for high sensitivity LC-MS/MS detection of salbutamol in porcine urine by Warren, Lee, Ali, Syed Atif, Leow, Chiuan Yee, Tan, Soo Choon, Leow, Chiuan Herng

“…[Display omitted] •Developed a proof-of-concept scFv-based immunochromatographic (IAC) assay to detect a widely misused substance, salbutamol.•The IAC assay…”
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Exploring shark VNAR antibody against infectious diseases using phage display technology by Lim, Hui Ting, Kok, Boon Hui, Leow, Chiuan Yee, Leow, Chiuan Herng

“…Antibody with high affinity and specificity to antigen has widely used as a tool to combat various diseases. The variable domain of immunoglobulin new antigen…”
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Schistosomiasis in Malaysia: A review by Chuah, Candy, Gobert, Geoffrey N., Latif, Baha, Heo, Chong Chin, Leow, Chiuan Yee

“…Schistosomiasis, a neglected tropical parasitic disease caused by the trematode flatworms of the genus Schistosoma, affects approximately 207 million people…”
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