Search Results - "Yee, Joyce"
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Karyopherin-mediated nucleocytoplasmic transport
Published in Nature reviews. Molecular cell biology (01-05-2022)“…Efficient and regulated nucleocytoplasmic trafficking of macromolecules to the correct subcellular compartment is critical for proper functions of the…”
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Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization
Published in Scientific reports (04-05-2018)“…ALS (Amyotrophic Lateral Sclerosis) is a neurodegenerative disease characterized by the redistribution of the RNA binding protein TDP-43 in affected neurons:…”
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Atomic basis of CRM1-cargo recognition, release and inhibition
Published in Seminars in cancer biology (01-08-2014)“…Abstract CRM1 or XPO1 is the major nuclear export receptor in the cell, which controls the nuclear-cytoplasmic localization of many proteins and RNAs. CRM1 is…”
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Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
Published in Cell (19-04-2018)“…Liquid-liquid phase separation (LLPS) is believed to underlie formation of biomolecular condensates, cellular compartments that concentrate macromolecules…”
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Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals
Published in eLife (10-03-2017)“…Nuclear export receptor CRM1 binds highly variable nuclear export signals (NESs) in hundreds of different cargoes. Previously we have shown that CRM1 binds…”
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Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex
Published in Proceedings of the National Academy of Sciences - PNAS (18-07-2023)“…Previously, we showed that the nuclear import receptor Importin-9 wraps around the H2A-H2B core to chaperone and transport it from the cytoplasm to the…”
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Anosmia caused by brain tumor
Published in The American journal of the medical sciences (01-01-2023)Get full text
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Predicting Fatigue-Associated Aberrant Driving Behaviors Using a Dynamic Weighted Moving Average Model With a Long Short-Term Memory Network Based on Heart Rate Variability
Published in Human factors (01-06-2024)“…Objective This study proposed a moving average (MA) approach to dynamically process heart rate variability (HRV) and developed aberrant driving behavior (ADB)…”
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Can Face- and Smartphone-Touching Behaviors Be Altered with Personal Hygiene Reminders during the COVID-19 Pandemic Period? An Observational Study
Published in International journal of environmental research and public health (01-10-2021)“…As part of the new measures to prevent the spread of the 2019 coronavirus disease (COVID-19), medical students were advised to wear a mask in class and avoid…”
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Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination
Published in Nature neuroscience (01-04-2015)“…In this study, the authors report the molecular characterization of orally bioavailable and blood-brain-barrier permeable inhibitors of the nuclear export…”
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Structural determinants of nuclear export signal orientation in binding to exportin CRM1
Published in eLife (08-09-2015)“…The Chromosome Region of Maintenance 1 (CRM1) protein mediates nuclear export of hundreds of proteins through recognition of their nuclear export signals…”
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Research Through Design: Twenty-First Century Makers and Materialities
Published in Design issues (01-07-2017)“…The Research Through Design conferences is a new, experimental dissemination platform to support design practitioner-researchers. “Research through design” has…”
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Aberrant Driving Behavior Prediction for Urban Bus Drivers in Taiwan Using Heart Rate Variability and Various Machine Learning Approaches: A Pilot Study
Published in Transportation research record (01-03-2023)“…Objective: Aberrant driving behavior (ADB) decreases road safety and is particularly relevant for urban bus drivers, who are required to drive daily shifts of…”
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Group A streptococcal pharyngitis
Published in BMJ case reports (30-09-2021)Get full text
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Similar early functional recovery after total knee replacement comparing single shot versus continuous saphenous nerve block: A randomised, double-blind trial
Published in Journal of orthopaedic surgery (Hong Kong) (01-01-2020)“…Purpose: Total knee replacement (TKR) is associated with post-operative pain. Femoral nerve block can relieve the pain but also affects the post-operative…”
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Machine learning model for aberrant driving behaviour prediction using heart rate variability: a pilot study involving highway bus drivers
Published in International journal of occupational safety and ergonomics (02-10-2023)“…Objectives. Current approaches via physiological features detecting aberrant driving behaviour (ADB), including speeding, abrupt steering, hard braking and…”
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Improving nutrition care and diet intake for hospitalised older people at risk of malnutrition through a nurse‐driven mealtime assistance bundle
Published in International journal of older people nursing (01-01-2024)“…Background Poor dietary intake is common in hospitalised older people. A targeted mealtime intervention is needed to improve nutrition care and dietary intake,…”
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Validation of a Personalized Hearing Screening Mobile Health Application for Persons with Moderate Hearing Impairment
Published in Journal of personalized medicine (16-10-2021)“…Hearing impairment is a frequent human sensory impairment. It was estimated that over 50% of those aged >75 years experience hearing impairment in the United…”
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Thyroglossal duct cysts in adults treated by ethanol sclerotherapy: A pilot study of a nonsurgical technique
Published in The Laryngoscope (01-06-2012)“…Objectives/Hypothesis: To investigate the effect of ethanol sclerotherapy on the thyroglossal duct cyst (TDC). Study Design: Prospective case series. Methods:…”
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