Search Results - "Yeboah, Kofi S"
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Bacterial Cyclic Dinucleotides and the cGAS-cGAMP-STING Pathway: A Role in Periodontitis?
Published in Pathogens (Basel) (30-05-2021)“…Host cells can recognize cytosolic double-stranded DNAs and endogenous second messengers as cyclic dinucleotides-including c-di-GMP, c-di-AMP, and cGAMP-of…”
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Journal Article -
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Identification of a Mycobacterium tuberculosis Cyclic Dinucleotide Phosphodiesterase Inhibitor
Published in ACS infectious diseases (12-02-2021)“…Immune cells sense bacteria-derived c-di-GMP and c-di-AMP as well as host-derived cGAMP, which is synthesized by cGAS upon binding to the pathogen’s DNA, to…”
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A STING-based fluorescent polarization assay for monitoring activities of cyclic dinucleotide metabolizing enzymes
Published in RSC chemical biology (01-02-2021)“…Cyclic dinucleoties, such as cGAMP, c-di-GMP and c-di-AMP, are fascinating second messengers with diverse roles in both prokaryotes and eukaryotes…”
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Journal Article