Search Results - "Yeargin, Jo"
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1
Early human prostate adenocarcinomas harbor androgen-independent cancer cells
Published in PloS one (25-09-2013)“…Although blockade of androgen receptor (AR) signaling represents the main treatment for advanced prostate cancer (PrCa), many patients progress to a lethal…”
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2
Suppression of acute lymphoblastic leukemia by the human wild-type p53 gene
Published in Cancer research (Chicago, Ill.) (1992)“…Independent mutations in both alleles of the p53 tumor suppressor gene are a frequent finding in human T-cell acute lymphoblastic leukemia (T-ALL) cell lines…”
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3
P53 mutation in acute T cell lymphoblastic leukemia is of somatic origin and is stable during establishment of T cell acute lymphoblastic leukemia cell lines
Published in The Journal of clinical investigation (01-05-1993)“…Samples donated by patients with T cell acute lymphoblastic leukemia (T-ALL) were screened for mutations of the p53 tumor suppressor gene. Peripheral blood…”
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4
Elevated levels of wild-type p53 induced by radiolabeling of cells leads to apoptosis or sustained growth arrest
Published in Current biology (01-04-1995)“…Background: The tumor suppressor protein p53 regulates progression through the checkpoint between the G1 and S phases of the cell cycle in response to…”
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5
Gain-of-function mutations of the p53 gene induce lymphohematopoietic metastatic potential and tissue invasiveness
Published in The American journal of pathology (01-09-1994)“…Leukemia cell infiltration and the induction of lethal hematopoietic disease in immune-deficient SCID mice transplanted with human T cell acute lymphoblastic T…”
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6
Nonhereditary p53 mutations in T-cell acute lymphoblastic leukemia are associated with the relapse phase
Published in Blood (15-05-1994)“…We have previously reported that greater than 60% of human leukemic T-cell lines possess mutations in the p53 tumor suppressor gene. To determine whether…”
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7
Insulin-like growth factor-I supports proliferation of autocrine thymic lymphoma cells with a pre-T cell phenotype
Published in The Journal of immunology (1950) (15-11-1990)“…We have studied the phenotypic characteristics and growth properties of murine T lymphoma cell lines derived from primary x-ray-induced thymic lymphomas at the…”
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8
Dissemination and tissue invasiveness in murine acute leukemia associated with acquisition of p53 mutation and loss of wild-type p53
Published in Molecular carcinogenesis (01-06-1995)“…Approximately 60% of mice treated with split-dose radiation develop leukemias that disseminate widely through the body, whereas 40% of the treated mice incur…”
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