Search Results - "Yeakey, Anne"

Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone by Stempel, David A, Raphiou, Ibrahim H, Kral, Kenneth M, Yeakey, Anne M, Emmett, Amanda H, Prazma, Charlene M, Buaron, Kathleen S, Pascoe, Steven J

“…Among more than 11,000 patients with moderate-to-severe asthma, fluticasone–salmeterol was noninferior to fluticasone alone with respect to severe asthma…”
Get full text

Safety of Adding Salmeterol to Fluticasone Propionate in Children with Asthma by Stempel, David A, Szefler, Stanley J, Pedersen, Søren, Zeiger, Robert S, Yeakey, Anne M, Lee, Laurie A, Liu, Andrew H, Mitchell, Herman, Kral, Kenneth M, Raphiou, Ibrahim H, Prillaman, Barbara A, Buaron, Kathleen S, Yun Kirby, Suyong, Pascoe, Steven J

“…This large trial involving children with asthma examined whether the addition of a long-acting beta-agonist to current therapy with inhaled glucocorticoids…”
Get full text

A review of the immunogenicity and safety of booster doses of omicron variant-containing mRNA-1273 COVID-19 vaccines in adults and children by Priddy, Frances, Chalkias, Spyros, Essink, Brandon, Whatley, Jordan, Brosz, Adam, Lee, Ivan T, Feng, Jing, Tracy, LaRee, Deng, Weiping, Zhou, Wen, Zhou, Honghong, Dixit, Avika, Schnyder-Ghamloush, Sabine, Girard, Bethany, de Windt, Elizabeth, Yeakey, Anne, Miller, Jacqueline, Das, Rituparna, Kuter, Barbara J

“…Vaccination against SARS-CoV-2 is an integral pillar of the public health approach to COVID-19. With the emergence of variants of concern that increase…”
Get full text

Enhanced passive surveillance of influenza vaccination in England, 2016−2017- an observational study using an adverse events reporting card by de Lusignan, Simon, Ferreira, Filipa, Damaso, Silvia, Byford, Rachel, Pathirannehelage, Sameera, Yeakey, Anne, Yonova, Ivelina, Schuind, Anne, Dos Santos, Gael

“…Influenza is a major public health burden, mainly prevented by vaccination. Recommendations on influenza vaccine composition are updated annually and constant…”
Get full text

Austri, a Large Randomized Study in Adolescents and Adults with Asthma, Assessing the Safety and Efficacy of Salmeterol in Combination with Fluticasone Propionate Compared to Fluticasone Propionate Alone by Stempel, David A., Dr, Raphiou, Ibrahim, Dr, Kral, Kenneth, Yeakey, Anne, Dr, Buaron, Kathy, Emmett, Amanda, Prazma, Charlene M., Dr, Pascoe, Steve, Dr

“…To declare non-inferiority the hazard ratio of subjects with a serious asthma-related event with FSC compared to FP was <2.0 based on the upper bound of the…”
Get full text

An evaluation of asthma medication utilization for risk evaluation and mitigation strategies (REMS) in the United States: 2005-2011 by DiSantostefano, Rachael L., Yeakey, Anne M., Raphiou, Ibrahim, Stempel, David A.

“…Abstract Purpose: The purpose of this study was to assess drug utilization patterns of fluticasone propionate (FP)/salmeterol (SAL) combination (FSC) and SAL…”
Get full text

Enhanced Safety Surveillance of GSK’s Quadrivalent Seasonal Influenza Vaccine in Belgium, Germany, and Spain for the 2018/19 Season: Interim Analysis by Dos Santos, Gael, Shende, Vishvesh, Damaso, Silvia, Yeakey, Anne

“…Introduction Influenza is an important cause of morbidity and mortality in Europe. Prevention by annual vaccination is most effective but with yearly vaccine…”
Get full text

Safety and immunogenicity of a single-dose omicron-containing COVID-19 vaccination in adolescents: an open-label, single-arm, phase 2/3 trial by Figueroa, Amparo L, Torres, Dania, Reyes-Acuna, Celia, Matherne, Paul, Yeakey, Anne, Deng, Weiping, Xu, Wenqin, Sigal, Yelena, Chambers, Greer, Olsen, Michelle, Girard, Bethany, Miller, Jacqueline M, Das, Rituparna, Priddy, Frances

“…Most individuals show immunity to SARS-CoV-2 from vaccination or infection, or both. We aimed to determine the safety and immunogenicity of an…”
Get full text

Effect of raxibacumab on immunogenicity of Anthrax Vaccine Adsorbed: a phase 4, open-label, parallel-group, randomised non-inferiority study by Skoura, Nancy, Wang-Jairaj, Jie, Della Pasqua, Oscar, Chandrasekaran, Vijayalakshmi, Billiard, Julia, Yeakey, Anne, Smith, William, Steel, Helen, Tan, Lionel K

“…Raxibacumab is a monoclonal antibody against protective antigen, which is the cell-binding part of Bacillus anthracis toxin, and is approved for treatment and…”
Get full text

Safety and Immunogenicity of an mRNA-1273 Booster in Children by Berthaud, Vladimir, Creech, C Buddy, Rostad, Christina A, Carr, Quito, De Leon, Liberation, Dietrich, Monika, Gupta, Anil, Javita, David, Nachman, Sharon, Pinninti, Swetha, Rathore, Mobeen, Rodriguez, Carina A, Luzuriaga, Katherine, Towner, William, Yeakey, Anne, Brown, Mollie, Zhao, Xiaoping, Deng, Weiping, Xu, Wenqin, Zhou, Honghong, Girard, Bethany, Kelly, Roxanne, Slobod, Karen, Anderson, Evan J, Das, Rituparna, Miller, Jacqueline, Schnyder Ghamloush, Sabine

“…A 2-dose mRNA-1273 primary series in children aged 6 months-5 years (25-µg) and 6-11 years (50-µg) had an acceptable safety profile and was immunogenic in the…”
Get full text

DREAMM-9: Phase I Study of Belantamab Mafodotin Plus Standard of Care in Patients with Transplant-Ineligible Newly Diagnosed Multiple Myeloma by Usmani, Saad Z., Alonso Alonso, Aránzazu, Quach, Hang, Koh, Youngil, Guenther, Andreas, Min, Chang-Ki, Zhou, Xiaoou L., Kaisermann, Morrys, Mis, Lukasz M., Williams, Danaè, Yeakey, Anne, Ferron-Brady, Geraldine, Figueroa, David J., Kremer, Brandon E., Gupta, Ira, Janowski, Wojciech

“…Introduction: The bortezomib, lenalidomide, and dexamethasone (VRd) regimen is an acceptable standard of care (SoC) for both transplant-eligible and…”
Get full text

Interim safety and immunogenicity of COVID-19 omicron BA.1 variant-containing vaccine in children in the USA: an open-label non-randomised phase 3 trial by Dixit, Avika, Bennett, Richard, Ali, Kashif, Griffin, Carl, Clifford, Robert A, Turner, Mark, Poston, Rosanne, Hautzinger, Kelly, Yeakey, Anne, Girard, Bethany, Zhou, Wen, Deng, Weiping, Zhou, Honghong, Schnyder Ghamloush, Sabine, Kuter, Barbara J, Slobod, Karen, Miller, Jacqueline M, Priddy, Frances, Das, Rituparna, Ali, Kashif, Ampajwala, Madhavi, Atz, Andrew, Bennett, Richard, Berman, Gary, Clifford, Robert, Dunn, Michael, Eder, Frank, Fuchs, George, Griffin, Carl, Hernandez, John M., Jeanfreau, Robert, Johnson, Kimball, Lavery, William, Meyer, Jay, Muller, William, Ohnmacht, Richard, Padhye, Amruta, Palanpurwala, Khozema, Rodrigue, Carina, Turner, Mark, Vasko, Todd, Waits, John, Warfield, Peter

“…Variant-containing mRNA vaccines for COVID-19 to broaden protection against SARS-CoV-2 variants are recommended based on findings in adults. We report interim…”
Get full text

DREAMM-5 platform trial: Belantamab mafodotin in combination with novel agents in patients with relapsed/refractory multiple myeloma (RRMM) by Richardson, Paul G., Biswas, Swethajit, Holkova, Beata, Jackson, Nicola, Netherway, Thelma, Paul, Sofia, Ferron-Brady, Geraldine, Yeakey, Anne, Shelton, Chris, Montes de Oca, Rocio, Ahlers, Christoph Matthias, Ballas, Marc S., Paul, Elaine Marie, Gupta, Ira, Opalinska, Joanna, Luptakova, Katarina

“…Abstract only TPS8552 Background: Single-agent belantamab mafodotin (GSK2857916), a B-cell maturation antigen targeting immunoconjugate, induced deep and…”
Get full text

DREAMM-6: Safety and tolerability of belantamab mafodotin in combination with bortezomib/dexamethasone in relapsed/refractory multiple myeloma (RRMM) by Nooka, Ajay K., Stockerl-Goldstein, Keith, Quach, Hang, Forbes, Adam, Mateos, Maria-Victoria, Khot, Amit, Tan, Alan, Abonour, Rafat, Chopra, Bikramjit, Rogers, Rachel, Ferron-Brady, Geraldine, Davidge, Jacqueline, Frey, Steve, Yeakey, Anne, Talekar, Mala, Luptakova, Katarina, Gupta, Ira, Popat, Rakesh

“…Abstract only 8502 Background: Belantamab mafodotin, a B-cell maturation antigen targeting immunoconjugate, demonstrated clinically meaningful, single-agent…”
Get full text

Dreamm-5: Platform Trial Evaluating Belantamab Mafodotin (a BCMA-directed Immuno-conjugate) in Combination with Novel Agents in Relapsed or Refractory Multiple Myeloma (RRMM) by Richardson, Paul G., Biswas, Swethajit, Holkova, Beata, Jackson, Nicola, Netherway, Thelma, Bao, Weichao, Ferron-Brady, Geraldine, Yeakey, Anne, Shelton, Chris, Montes De Oca, Rocio, Ahlers, Chris, Franco, Sonia, Ballas, Marc, Paul, Elaine, Luptakova, Katarina, Gupta, Ira, Opalinska, Joanna

“…Background: Patients with RRMM who have relapsed through multiple prior lines of therapy need novel, effective, targeted agents. B-cell maturation antigen…”
Get full text

367. Safety and Immunogenicity of a 50-μg mRNA-1273 Vaccine Booster for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) in Adolescents by Figueroa, Amparo, Ali, Kashif, Berman, Gary, Zhou, Honghong, Deng, Weiping, Patel, Monali, Girard, Bethany, Yeakey, Anne, Slobod, Karen, Priddy, Frances, Miller, Jacqueline, Das, Rituparna

“…Abstract Background Increased community COVID-19 cases prompted the clinical evaluation of an mRNA-1273 booster dose (BD) in TeenCOVE adolescent participants…”
Get full text

DREAMM-6: Safety, Tolerability and Clinical Activity of Belantamab Mafodotin (Belamaf) in Combination with Bortezomib/Dexamethasone (BorDex) in Relapsed/Refractory Multiple Myeloma (RRMM) by Popat, Rakesh, Nooka, Ajay, Stockerl-Goldstein, Keith, Abonour, Rafat, Ramaekers, Ryan, Khot, Amit, Forbes, Adam, Lee, Cindy, Augustson, Bradley, Spencer, Andrew, Mateos, Maria-Victoria, Chopra, Bikramjit, Rogers, Rachel, Smith, Deborah A, Davidge, Jacqueline, Montes de Oca, Rocio, Ferron-Brady, Geraldine, Yeakey, Anne, Talekar, Mala, Kremer, Brandon E., Gupta, Ira, Quach, Hang

“…Introduction: Single-agent belamaf (GSK2857916), a B-cell maturation antigen-targeting antibody-drug conjugate, demonstrated deep and durable responses with a…”
Get full text

Brand-Specific Enhanced Safety Surveillance of GSK’s Quadrivalent Seasonal Influenza Vaccine in Belgium, Germany and Spain for the 2018/2019 Season by Dos Santos, Gael, Nguyen, Bach-Yen, Damaso, Silvia, Godderis, Lode, Martínez-Gómez, Xavier, Eckermann, Tamara, Loos, Hugo, Salamanca de la Cueva, Ignacio, Shende, Vishvesh, Schmidt, Alexander C., Yeakey, Anne

“…Introduction Seasonal influenza causes numerous deaths worldwide each year. Annual vaccination for disease prevention is crucial. Seasonal vaccines are updated…”
Get full text

Safety and durability of mRNA-1273–induced SARS-CoV-2 immune responses in adolescents: results from the phase 2/3 TeenCOVE trial by Figueroa, Amparo L., Ali, Kashif, Berman, Gary, Zhou, Honghong, Deng, Weiping, Xu, Wenqin, Lussier, Stephanie, Girard, Bethany, Dutko, Frank J., Slobod, Karen, Yeakey, Anne, Priddy, Frances, Miller, Jacqueline M., Das, Rituparna

“…Longitudinal changes in vaccination-induced immune response remain inadequately characterized in adolescents. We present long-term safety, immunogenicity, and…”
Get full text

Safety and durability of mRNA-1273–induced SARS-CoV-2 immune responses in adolescents: results from the phase 2/3 TeenCOVE trialResearch in context by Amparo L. Figueroa, Kashif Ali, Gary Berman, Honghong Zhou, Weiping Deng, Wenqin Xu, Stephanie Lussier, Bethany Girard, Frank J. Dutko, Karen Slobod, Anne Yeakey, Frances Priddy, Jacqueline M. Miller, Rituparna Das

“…Background: Longitudinal changes in vaccination-induced immune response remain inadequately characterized in adolescents. We present long-term safety,…”
Get full text