Search Results - "Yeager, L."

Potential mechanisms of target-independent uptake and toxicity of antibody-drug conjugates by Mahalingaiah, Prathap Kumar, Ciurlionis, Rita, Durbin, Kenneth R., Yeager, Ronnie L., Philip, Binu K., Bawa, Bhupinder, Mantena, Srinivasa R., Enright, Brian P., Liguori, Michael J., Van Vleet, Terry R.

“…Antibody-drug conjugates (ADCs) are a promising therapeutic modality for oncology indications. The concept of an ADC platform is to increase the therapeutic…”
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Introducing the “TCDD-Inducible AhR-Nrf2 Gene Battery” by Yeager, Ronnie L., Reisman, Scott A., Aleksunes, Lauren M., Klaassen, Curtis D.

“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces genes via the transcription factor aryl hydrocarbon receptor (AhR), including Cyp1a1, NAD(P)H:quinone…”
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Paddlebots: Translation of Rotating Colloidal Assemblies near an Air/Water Interface by Wolvington, E., Yeager, L., Gao, Y., Zimmermann, C.J., Marr, D.W.M.

“…Microbot propulsion requires unique strategies due to the dominance of viscosity and the reversible nature of microscale flows. To address this, swimmers of…”
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Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet by Zhang, Yu-Kun Jennifer, Yeager, Ronnie L., Tanaka, Yuji, Klaassen, Curtis D.

“…Oxidative stress has been proposed as an important promoter of the progression of fatty liver diseases. The current study investigates the potential functions…”
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An Unexpected Synergist Role of P-Glycoprotein and Breast Cancer Resistance Protein on the Central Nervous System Penetration of the Tyrosine Kinase Inhibitor Lapatinib (N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine; GW572016) by Polli, Joseph W, Olson, Katie L, Chism, John P, John-Williams, Lisa St, Yeager, Russell L, Woodard, Sesha M, Otto, Vicky, Castellino, Stephen, Demby, Victoria E

“…Lapatinib is a tyrosine kinase inhibitor approved for use in combination with capecitabine to treat advanced or metastatic breast cancers overexpressing human…”
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NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet by Tanaka, Yuji, Aleksunes, Lauren M, Yeager, Ronnie L, Gyamfi, Maxwell A, Esterly, Noriko, Guo, Grace L, Klaassen, Curtis D

“…NF-E2-related factor 2 (Nrf2) is a transcription factor that is activated by oxidative stress and electrophiles that regulates the expression of numerous…”
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Circadian Expression Profiles of Drug-Processing Genes and Transcription Factors in Mouse Liver by ZHANG, Yu-Kun Jennifer, YEAGER, Ronnie L, KLAASSEN, Curtis D

“…Temporal coordination of hepatic drug-processing gene (DPG) expression facilitates absorption, biotransformation, and excretion of exogenous and endogenous…”
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Randomized clinical trial of a brief, scalable intervention for mental health sequelae in college students during the COVID-19 pandemic by Rizvi, Shireen L., Finkelstein, Jesse, Wacha-Montes, Annmarie, Yeager, April L., Ruork, Allison K., Yin, Qingqing, Kellerman, John, Kim, Joanne S., Stern, Molly, Oshin, Linda A., Kleiman, Evan M.

“…This randomized clinical trial aimed to determine feasibility, acceptability, and initial efficacy of brief Dialectical Behavior Therapy (DBT) skills videos in…”
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A System Level Analysis of Coastal Ecosystem Responses to Hurricane Impacts by Patrick, C. J., Yeager, L., Armitage, A. R., Carvallo, F., Congdon, V. M., Dunton, K. H., Fisher, M., Hardison, A. K., Hogan, J. D., Hosen, J., Hu, X., Reese, B. Kiel, Kinard, S., Kominoski, J. S., Lin, X., Liu, Z., Montagna, P. A., Pennings, S. C., Walker, L., Weaver, C. A., Wetz, M.

“…Tropical cyclones are major disturbances for coastal systems. Hurricane Harvey made landfall in Texas, USA, on August 25, 2017 as a category 4 storm. There…”
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Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice by Aleksunes, Lauren M, Reisman, Scott A, Yeager, Ronnie L, Goedken, Michael J, Klaassen, Curtis D

“…The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) induces a battery of cytoprotective genes after oxidative stress. Nrf2 aids in…”
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Commonly prescribed medications and potential false-positive urine drug screens by Brahm, Nancy C, Yeager, Lynn L, Fox, Mark D, Farmer, Kevin C, Palmer, Tony A

“…The implications of potential false-positive urine drug screen (UDS) results for patients receiving commonly prescribed medications were evaluated. A…”
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Design and rationale of the Fontan Udenafil Exercise Longitudinal (FUEL) trial by Goldberg, David J., Zak, Victor, Goldstein, Bryan H., McCrindle, Brian W., Menon, Shaji C., Schumacher, Kurt R., Payne, R. Mark, Rhodes, Jonathan, McHugh, Kimberly E., Penny, Daniel J., Trachtenberg, Felicia, Hamstra, Michelle S., Richmond, Marc E., Frommelt, Peter C., Files, Matthew D., Yeager, James L., Pemberton, Victoria L., Stylianou, Mario P., Pearson, Gail D., Paridon, Stephen M.

“…The Fontan operation creates a circulation characterized by elevated central venous pressure and low cardiac output. Over time, these characteristics result in…”
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Diet variation of a generalist fish predator, grey snapper Lutjanus griseus, across an estuarine gradient: trade-offs of quantity for quality? by Yeager, L. A., Layman, C. A., Hammerschlag-Peyer, C. M.

“…This study examined diet, prey quality and growth for a generalist fish predator, grey snapper Lutjanus griseus, at five sites across an estuarine gradient in…”
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Predictors of severe right ventricular failure after implantable left ventricular assist device insertion: analysis of 245 patients by Ochiai, Yoshie, McCarthy, Patrick M, Smedira, Nicholas G, Banbury, Michael K, Navia, Jose L, Feng, Jingyuan, Hsu, Amy P, Yeager, Michael L, Buda, Tiffany, Hoercher, Katherine J, Howard, Michael W, Takagaki, Masami, Doi, Kazuyoshi, Fukamachi, Kiyotaka

“…Insertion of an implantable left ventricular assist device (LVAD) complicated by early right ventricular (RV) failure has a poor prognosis and is largely…”
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Results of a Phase I/II Multi-Center Investigation of Udenafil in Adolescents after Fontan Palliation by Goldberg, David J, Zak, Victor, Goldstein, Bryan H, Chen, Shan, Hamstra, Michelle S, Radojewski, Elizabeth A, Maunsell, Eileen, Mital, Seema, Menon, Shaji C, Schumacher, Kurt R, Payne, R. Mark, Stylianou, Mario, Kaltman, Jonathan R, deVries, Tina M, Yeager, James L, Paridon, Stephen M

“…Background The Fontan operation results in a circulation that is dependent on low pulmonary vascular resistance to maintain an adequate cardiac output. Medical…”
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Ethical decision making by Yeager, Arthur L., DMD, MMH

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Clinical and experimental applications of NIR-LED photobiomodulation by Desmet, Kristina D, Paz, David A, Corry, Jesse J, Eells, Janis T, Wong-Riley, Margaret T T, Henry, Michele M, Buchmann, Ellen V, Connelly, Mary P, Dovi, Julia V, Liang, Huan Ling, Henshel, Diane S, Yeager, Ronnie L, Millsap, Deborah S, Lim, Jinhwan, Gould, Lisa J, Das, Rina, Jett, Marti, Hodgson, Brian D, Margolis, David, Whelan, Harry T

“…This review presents current research on the use of far-red to near-infrared (NIR) light treatment in various in vitro and in vivo models. Low-intensity light…”
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Social support as protective factor for suicidal ideation during treatment for substance abuse: Differential effects across treatment modalities by Grove, Jeremy L., Yeager, April L., Kleiman, Evan M.

“…•Social support predicted odds of suicidal ideation (SI) in substance use patients.•Contact with one's social support system predicted lower mid-treatment SI…”
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Critical Care RNs Engage in Releasing time to care™: Transforming RN Practice by Domm, E, Russell, T, Parsons, L, Myrah, M, Etner, D, Gerbrandt, S, Yeager, L

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A preventive approach to obstetric care in a rural hospital: association between higher rates of preventive labor induction and lower rates of cesarean delivery by Nicholson, James M, Yeager, David L, Macones, George

“…Annual cesarean delivery rates in North America are increasing. Despite the morbidity associated with cesarean delivery, a safe preventive strategy to reduce…”
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