Search Results - "Yeşim Karasulu, H"

Preparation and evaluation of a lipid-based drug delivery system to ımprove valsartan oral bioavailability: pharmacokinetic and pharmacodynamic analysis by Gülmezoğlu, Eda, Yıldız Türkyılmaz, Gülbeyaz, Karasulu, H. Yeşim

“…Antihypertensive treatment reduces the risk of cardiovascular complications in patients with high mortality with hypertension. Valsartan is highly selective…”
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In vitro evaluation and in vivo efficacy studies of a liposomal doxorubicin-loaded glycyrretinic acid formulation for the treatment of hepatocellular carcinoma by Diril, Mine, Özdokur, Kemal Volkan, Yıldırım, Yeliz, Karasulu, H Yeşim

“…Hepatocellular carcinoma (HCC), more than 800 000 cases reported annually, is the most common primary liver cancer globally. Doxorubicin hydrochloride…”
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Evaluation of skin permeation and anti-inflammatory and analgesic effects of new naproxen microemulsion formulations by Üstündağ Okur, Neslihan, Apaydın, Şebnem, Karabay Yavaşoğlu, N. Ülkü, Yavaşoğlu, Altuğ, Karasulu, H. Yeşim

“…New microemulsion formulation of Np exerted a stronger anti inflammatory and analgesic activity when compared to commercial product. The aim of this study was…”
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Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+) (S)-naproxen derivatives by Birgül, Kaan, Yıldırım, Yeliz, Karasulu, H. Yeşim, Karasulu, Ercüment, Uba, Abdullah Ibrahim, Yelekçi, Kemal, Bekçi, Hatice, Cumaoğlu, Ahmet, Kabasakal, Levent, Yılmaz, Özgür, Küçükgüzel, Ş. Güniz

“…In this study, (S)-naproxen thiosemicarbazides (3a-d), 1,2,4-triazoles (4a-c), triazole-thioether hybride compounds (5a-p) were synthesized and their…”
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Preparation and evaluation of novel microemulsion-based hydrogels for dermal delivery of benzocaine by Üstündağ Okur, Neslihan, Çağlar, Emre Şefik, Arpa, Muhammet Davut, Karasulu, H. Yeşim

“…The purpose of the current research was to prepare and evaluate the potential use of microemulsion-based hydrogel (MBH) formulations for dermal delivery of…”
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Formulation and In Vitro Evaluation of Self Microemulsifying Drug Delivery System Containing Atorvastatin Calcium by Diril, Mine, Türkyılmaz, Gülbeyaz Yıldız, Karasulu, H Yeşim

“…The aim of this study was to develop a new dosage form as an alternative to the classical tablet forms of atorvastatin calcium (AtrCa). The formulation…”
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Comparison of different water/oil microemulsions containing diclofenac sodium: preparation, characterization, release rate, and skin irritation studies by Kantarci, Gülten, Ozgüney, Işik, Karasulu, H Yeşim, Arzik, Sevgi, Güneri, Tamer

“…The aim of the present study was to make a comparison of the in vitro release rate of diclofenac sodium (DS) from microemulsion (M) vehicles containing soybean…”
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Aprotinin revisited: formulation, characterization, biodistribution and therapeutic potential of new aprotinin microemulsion in acute pancreatitis by Karasulu, H. Yeşim, Oruç, Nevin, Üstündağ-Okur, Neslihan, İlem Özdemir, Derya, Ay Şenyiğit, Zeynep, Barbet Yılmaz, Funda, Aşıkoğlu, Makbule, Özkılıç, Hayal, Akçiçek, Eren, Güneri, Tamer, Özütemiz, Ömer

“…The aim of this study was to develop aprotinin-loaded microemulsion (M A ) for intravenous administration and evaluate the biodistribution and therapeutic…”
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Assessment of Aprotinin Loaded Microemulsion Formulations for Parenteral Drug Delivery: Preparation, Characterization, in vitro Release and Cytotoxicity Studies by Okur, Neslihan Üstündağ, Özdemir, Derya İlem, Kahyaoğlu, Şennur Görgülü, Şenyiğit, Zeynep Ay, Aşıkoğlu, Makbule, Genç, Lütfi, Karasulu, H Yeşim

“…The object of the current study was to prepare novel microemulsion formulations of aprotinin for parenteral delivery and to compare in vitro characteristics…”
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Permeation Studies of Indomethacin from Different Emulsions for Nasal Delivery and Their Possible Anti-Inflammatory Effects by Karasulu, H. Yeşim, Şanal, Z. Evren, Sözer, Sumru, Güneri, Tamer, Ertan, Gökhan

“…The purpose of this research was to develop an emulsion formulation of indomethacin (IND) suitable for nasal delivery. IND was incorporated into the oil phases…”
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Controlled release of methotrexate from w/o microemulsion and its in vitro antitumor activity by Karasulu, H Yesim, Karabulut, Bülent, Göker, Erdem, Güneri, Tamer, Gabor, Franz

“…The objective of this study was to prepare the microemulsion of methotrexate (M-MTX) for oral use and to investigate the suppressive effect of MTX-loaded…”
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Permeation studies and histological examination of sheep nasal mucosa following administration of different nasal formulations with or without absorption enhancers by Karasulu, Ercüment, Yavasoğlu, Altug, Evrensanal, Z, Uyanikgil, Yigit, Karasulu, H Yesim

“…This study was designed to investigate the possible histological effects of different intranasal (IN) formulations of indomethacin (IND) on nasal mucosa in…”
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Effect of microemulsion formulation on biodistribution of 99m Tc-Aprotinin in acute pancreatitis models induced rats by İlem-Özdemir, Derya, Üstündağ-Okur, Neslihan, Ay Şenyiğit, Zeynep, Oruç, Nevin, Aşıkoğlu, Makbule, Özütemiz, Ömer, Karasulu, H Yeşim

“…Aprotinin is a monomeric globular polypeptide, which derived from bovine lung tissue and theoretically attractive molecule in ameliorating the effects of acute…”
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Preparation of arsenic trioxide-loaded microemulsion and its enhanced cytotoxicity on MCF-7 breast carcinoma cell line by Karasulu, H Yeşim, Karabulut, Bülent, Kantarci, Gülten, Ozgüney, Işik, Sezgin, Canfeza, Sanli, Ulus Ali, Göker, Erdem

“…In this study, an injectable microemulsion of arsenic trioxide (As2O3-M) was prepared for intratumoral injection and the suppressive effect of As2O3-loaded…”
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Extended release lipophilic indomethacin microspheres: formulation factors and mathematical equations fitted drug release rates by Karasulu, Ercüment, Yeşim Karasulu, H, Ertan, Gökhan, Kirilmaz, Levent, Güneri, Tamer

“…Extended release liphophilic microspheres of indomethacin were prepared using cetostearyl alcohol (CsA), stearyl alcohol (SA) and cetyl alcohol (CA) in the…”
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Microemulsions as novel drug carriers: the formation, stability, applications and toxicity by Karasulu, H Yesim

“…A microemulsion, made from water, oil, surfactants and cosurfactant is a thermodynamically stable system. The presence of the cosurfactant is often required in…”
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Efficacy of a new ketoconazole bioadhesive vaginal tablet on Candida albicans by Karasulu, H.Yeşim, Hilmioğlu, Süleyha, Metin, Dilek Y, Güneri, Tamer

“…To develop more effective treatment for vaginal candidasis, ketoconazole (KTZ) was formulated in bioadhesive tablet formulations that increase the time of…”
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Different geometric shaped hydrogel theophylline tablets: statistical approach for estimating drug release by Karasulu, H.Yeşim, Ertan, Gökhan

“…The objective of this study was to develop a mathematical equation for the calculation of drug release from different shaped matrix tablets. By this way,…”
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3(3) factorial design-based optimization of the formulation of nitrofurantoin microcapsules by Karasulu, H Y, Ertan, G, Günerï, T

“…A microcapsule form of nitrofurantoin was prepared by a simple coacervation method with carboxymethylcellulose and aluminium sulfate. 3(3) factorial design was…”
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