Search Results - "Ye, Yuanhua"
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Reduced ELABELA expression attenuates trophoblast invasion through the PI3K/AKT/mTOR pathway in early onset preeclampsia
Published in Placenta (Eastbourne) (01-11-2019)“…Early onset preeclampsia is linked to abnormal trophoblast invasion, leading to insufficient recasting of uterine spiral arteries and shallow placental…”
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Activation of HO-1 protects placental cells function in oxidative stress via regulating ZO-1/occludin
Published in Biochemical and biophysical research communications (16-04-2019)“…We previously confirmed that Nuclear factor erythroid 2-related factor-2 (Nrf2) and heme oxygenase (HO-1) play synergistic roles in the pathogenesis of…”
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MiR-326 inhibits trophoblast growth, migration, and invasion by targeting PAX8 via Hippo pathway
Published in Reproductive biology and endocrinology (24-02-2022)“…Preeclampsia (PE), a pregnancy disorder that affects 5-7% of pregnant women, is among the primary causes for maternal and perinatal mortality. PE is believed…”
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Efficacy of resuscitative endovascular balloon occlusion of the aorta for hemorrhage control in patients with abnormally invasive placenta: a historical cohort study
Published in BMC pregnancy and childbirth (10-05-2023)“…Patients with abnormally invasive placenta (AIP) are at high risk of massive postpartum hemorrhage. Resuscitative endovascular balloon occlusion of the aorta…”
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Progesterone inhibited endoplasmic reticulum stress associated apoptosis induced by interleukin‐1β via the GRP78/PERK/CHOP pathway in BeWo cells
Published in The journal of obstetrics and gynaecology research (01-03-2018)“…Aim Pre‐eclampsia (PE) is a pregnancy complication characterized by new onset maternal hypertension and proteinuria. Its underlying mechanisms are unclear…”
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Accumulation of Advanced Glycation End Products Involved in Inflammation and Contributing to Severe Preeclampsia, in Maternal Blood, Umbilical Blood and Placental Tissues
Published in Gynecologic and obstetric investigation (01-01-2017)“…To investigate the expression of advanced glycation end products (AGEs) and the receptor for AGE (RAGEs) in maternal blood, umbilical blood and placental…”
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Role of IL-17 Variants in Preeclampsia in Chinese Han Women
Published in PloS one (09-10-2015)“…Previous studies have suggested an important role for IL-17, mainly secreted by Th17 cells, in the development of systemic inflammation in preeclampsia (PE)…”
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Chorionic villus-derived mesenchymal stem cell-mediated NRG1 upregulation promotes HTR-8/SVneo cells proliferation through the activation of the NF-κB signaling pathway
Published in Heliyon (01-08-2023)“…In a prior study, our group found that chorionic villus-derived mesenchymal stem cells (CV-MSCs) were capable of promoting trophoblast proliferative and…”
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Interleukin-1β-31C/T and -511T/C polymorphisms were associated with preeclampsia in Chinese Han population
Published in PloS one (15-09-2014)“…The purpose of our study is to investigate the relationship between IL-1β -31C/T (rs1143627) and -511T/C (rs16944) polymorphisms and the preeclampsia (PE), and…”
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Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes the proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway
Published in Cell & bioscience (13-10-2021)“…Abstract Background Trophoblast dysfunction during pregnancy is fundamentally involved in preeclampsia. Several studies have revealed that human chorionic…”
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Amnion-Derived Mesenchymal Stem Cell Exosomes-Mediated Autophagy Promotes the Survival of Trophoblasts Under Hypoxia Through mTOR Pathway by the Downregulation of EZH2
Published in Frontiers in cell and developmental biology (11-11-2020)“…Human amnion-derived mesenchymal stem cells (AD-MSCs) have been reported as a promising effective treatment to repair tissue. Trophoblast dysfunction during…”
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Downregulation of receptor tyrosine kinase-like orphan receptor 1 in preeclampsia placenta inhibits human trophoblast cell proliferation, migration, and invasion by PI3K/AKT/mTOR pathway accommodation
Published in Placenta (Eastbourne) (01-07-2019)“…Invasive deficiency of the trophoblast and poor remodeling of the uterine spiral arteries were probably the primary pathogenesis causes of preeclampsia (PE)…”
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Increased NDRG1 expression suppresses angiogenesis via PI3K/AKT pathway in human placental cells
Published in Pregnancy hypertension (01-07-2020)“…•NDRG1 knockdown significantly increased angiogenesis in JEG-3 cells.•NDRG1 specifically binds to PI3K.•NDRG1 may inhibit angiogenesis through reduction of…”
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STAT3 activation by IL-6 from adipose-derived stem cells promotes endometrial carcinoma proliferation and metastasis
Published in Biochemical and biophysical research communications (07-06-2018)“…Endometrial cancer is the most common gynaecological cancer, and its incidence is increasing. Obesity is a well-recognized risk factor for endometrial cancer,…”
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Increased NDRG1 expression attenuate trophoblast invasion through ERK/MMP-9 pathway in preeclampsia
Published in Placenta (Eastbourne) (01-03-2017)“…Abstract Objective The aim of this study was to investigate the expression of N -myc downstream-regulated gene1(NDRG1)in the placentas of pregnancies…”
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Adipose‐derived mesenchymal stem cells induced PAX8 promotes ovarian cancer cell growth by stabilizing TAZ protein
Published in Journal of cellular and molecular medicine (01-05-2021)“…Our previous studies have shown that the Adipose‐derived mesenchymal stem cells (ADSCs) can regulate metastasis and development of ovarian cancer. However, its…”
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Autophagy protects against oxidized low density lipoprotein-mediated inflammation associated with preeclampsia
Published in Placenta (Eastbourne) (01-12-2016)“…Abstract Introduction Inflammatory responses play an important role in the pathogenesis of preeclampsia. Recently, the anti-inflammatory role played by…”
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Complement Split Products C3a/C5a and Receptors: Are They Regulated by Circulating Angiotensin II Type 1 Receptor Autoantibody in Severe Preeclampsia?
Published in Gynecologic and obstetric investigation (01-01-2016)“…This study measured the serum levels of complement component (C)3a and C5a and the placental expressions of C3a receptor (R) and C5aR to determine a potential…”
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Genetic susceptibility analysis of GCLC rs17883901 polymorphism to preeclampsia in Chinese Han women
Published in Gynecological endocrinology (01-09-2020)“…Preeclampsia (PE) is a specific obstetric disorder that may result in maternal and neonatal morbidity and mortality. Increasing evidence has been indicated…”
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Human placental lactogen mRNA in maternal plasma play a role in prenatal diagnosis of abnormally invasive placenta: yes or no?
Published in Gynecological endocrinology (03-07-2019)“…Objective: To determine whether maternal plasma human placental lactogen (hPL) mRNA levels can predict abnormally invasive placenta. Study design: Sixty-eight…”
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