Search Results - "Ye, YaYi"
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Precise pancreatic cancer therapy through targeted degradation of mutant p53 protein by cerium oxide nanoparticles
Published in Journal of nanobiotechnology (01-04-2023)“…In a significant proportion of cancers, point mutations of TP53 gene occur within the DNA-binding domain, resulting in an abundance of mutant p53 proteins…”
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Enhancing anti-tumor effect of ultrasensitive bimetallic RuCu nanoparticles as radiosensitizers with dual enzyme-like activities
Published in Biomaterials (01-11-2022)“…Radiotherapy (RT), through the generation of reactive oxygen species (ROS) and DNA damage to tumor cells caused by high-energy irradiation, has been a widely…”
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Harnessing a triphenylphosphine-based AIE nano-platform for triggering incomplete mitophagy to continuously augment anti-tumor immune response in hepatocellular carcinoma
Published in Nano today (01-02-2024)“…Hepatocellular carcinoma (HCC) ranks as the second leading cause of cancer-related mortality globally, with an escalating incidence. However, HCC exhibits a…”
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Photodynamic Modulation of Endoplasmic Reticulum and Mitochondria Network Boosted Cancer Immunotherapy
Published in Advanced materials (Weinheim) (01-01-2024)“…Immunogenic cell death (ICD) represents a promising approach for enhancing tumor therapy efficacy by inducing antitumor immune response. However, current ICD…”
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Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins
Published in ACS applied materials & interfaces (11-01-2023)“…TP53 missense mutations that express highly stabilized mutant p53 protein (mutp53) driving tumorigenesis have been witnessed in a considerable percentage of…”
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NIR Emissive Functional Nanoparticles Promote Precise Pancreatic Cancer Therapy by Co‐Targeting Mutant p53 and Oncogenic KRAS
Published in Advanced functional materials (01-05-2024)“…Pancreatic ductal adenocarcinoma (PDAC) presents a formidable global health challenge. Targeting genetic aberrations, particularly KRAS and TP53 mutations,…”
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Bxbl integrase serves as a highly efficient DNA recombinase in rapid metabolite pathway assembly
Published in 生物化学与生物物理学报:英文版 (2017)“…Phage-encoded serine integrases are widely used in genetic engineering. They also have the potential to serve as efficient DNA assemblers, demonstrated by the…”
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