Search Results - "Ye, Willy G."

Connexin45 (GJC1) loss-of-function mutation contributes to familial atrial fibrillation and conduction disease by Li, Ruo-Gu, Xu, Ying-Jia, Ye, Willy G., Li, Yan-Jie, Chen, Honghong, Qiu, Xing-Biao, Yang, Yi-Qing, Bai, Donglin

“…Atrial fibrillation (AF) represents the most common clinical cardiac arrhythmia and substantially increases the risk of cerebral stroke, heart failure, and…”
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Atrial fibrillation-linked germline GJA5/connexin40 mutants showed an increased hemichannel function by Sun, Yiguo, Hills, Matthew D, Ye, Willy G, Tong, Xiaoling, Bai, Donglin

“…Mutations in GJA5 encoding the gap junction protein connexin40 (Cx40) have been linked to lone atrial fibrillation. Some of these mutants result in impaired…”
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Engineered Cx40 variants increased docking and function of heterotypic Cx40/Cx43 gap junction channels by Jassim, Arjewan, Aoyama, Hiroshi, Ye, Willy G, Chen, Honghong, Bai, Donglin

“…Abstract Gap junction (GJ) channels provide low resistance passages for rapid action potential propagation in the heart. Both connexin40 (Cx40) and Cx43 are…”
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Discovery of GJC1 (Cx45) as a New Gene Underlying Congenital Heart Disease and Arrhythmias by Li, Yan-Jie, Wang, Juan, Ye, Willy G, Liu, Xing-Yuan, Li, Li, Qiu, Xing-Biao, Chen, Honghong, Xu, Ying-Jia, Yang, Yi-Qing, Bai, Donglin, Huang, Ri-Tai

“…As the most prevalent type of birth malformation, congenital heart disease (CHD) gives rise to substantial mortality and morbidity as well as a socioeconomic…”
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Junctional delay, frequency, and direction-dependent uncoupling of human heterotypic Cx45/Cx43 gap junction channels by Ye, Willy G., Yue, Benny, Aoyama, Hiroshi, Kim, Nicholas K., Cameron, John A., Chen, Honghong, Bai, Donglin

“…Gap junction (GJ) channels form low resistance passages between cardiomyocytes and play a role in the rapid propagation of action potentials in the heart. A GJ…”
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Engineered Cx40 Variants Showed Heterotypic Colocalization and Increased GAP Junctional Coupling with Cx43 by Jassim, Arjewan, Aoyama, Hiroshi, Ye, Willy G., Chen, Honghong, Bai, Donglin

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Discovery of IGJC1/I as a New Gene Underlying Congenital Heart Disease and Arrhythmias by Li, Yan-Jie, Wang, Juan, Ye, Willy G, Liu, Xing-Yuan, Li, Li, Qiu, Xing-Biao, Chen, Honghong, Xu, Ying-Jia, Yang, Yi-Qing, Bai, Donglin, Huang, Ri-Tai

“…Congenital heart disease is associated with substantial mortality and morbidity as well as socioeconomic burden, and increasing research underscores the…”
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Function Study of Atrial Fibrillation-Linked Connexin Mutants and Heterotypic Docking Compatibility of Cardiac Connexins by Ye, Willy G

“…Gap junctions are critical for the propagation of action potentials in the heart. Many autosomal dominant Cx40 mutations have been linked to atrial…”
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