Search Results - "Ye, Siying"

Inhibition of reactive oxygen species production ameliorates inflammation induced by influenza A viruses via upregulation of SOCS1 and SOCS3 by Ye, Siying, Lowther, Sue, Stambas, John

“…Highly pathogenic avian influenza virus infection is associated with severe mortality in both humans and poultry. The mechanisms of disease pathogenesis and…”
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Extracellular Matrix Enzymes and Immune Cell Biology by McMahon, Meagan, Ye, Siying, Pedrina, Jess, Dlugolenski, Daniel, Stambas, John

“…Remodelling of the extracellular matrix (ECM) by ECM metalloproteinases is increasingly being associated with regulation of immune cell function. ECM…”
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Long-distance delivery of bacterial virulence factors by Pseudomonas aeruginosa outer membrane vesicles by Bomberger, Jennifer M, Maceachran, Daniel P, Coutermarsh, Bonita A, Ye, Siying, O'Toole, George A, Stanton, Bruce A

“…Bacteria use a variety of secreted virulence factors to manipulate host cells, thereby causing significant morbidity and mortality. We report a mechanism for…”
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ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity by McMahon, Meagan, Ye, Siying, Izzard, Leonard, Dlugolenski, Daniel, Tripp, Ralph A, Bean, Andrew G D, McCulloch, Daniel R, Stambas, John

“…The extracellular matrix (ECM) provides physical scaffolding for cellular constituents and initiates biochemical and biomechanical cues that are required for…”
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A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system by Bomberger, Jennifer M, Ye, Siying, Maceachran, Daniel P, Koeppen, Katja, Barnaby, Roxanna L, O'Toole, George A, Stanton, Bruce A

“…Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen chronically infecting the lungs of patients with chronic obstructive pulmonary disease…”
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Correction: ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity by McMahon, Meagan, Ye, Siying, Izzard, Leonard, Dlugolenski, Daniel, Tripp, Ralph A, Bean, Andrew G. D, McCulloch, Daniel R, Stambas, John

“…Cleavage of versican by ADAMTS5 removes the ECM blockade, allowing migration (top panel). [...]versican accumulation in the absence of ADAMTS enzyme activity…”
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c-Cbl Facilitates Endocytosis and Lysosomal Degradation of Cystic Fibrosis Transmembrane Conductance Regulator in Human Airway Epithelial Cells by Ye, Siying, Cihil, Kristine, Stolz, Donna Beer, Pilewski, Joseph M., Stanton, Bruce A., Swiatecka-Urban, Agnieszka

“…Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated Cl− channel expressed in the apical membrane of fluid-transporting epithelia…”
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Pseudomonas aeruginosa Secreted Protein PA2934 Decreases Apical Membrane Expression of the Cystic Fibrosis Transmembrane Conductance Regulator by MacEachran, Daniel P, Ye, Siying, Bomberger, Jennifer M, Hogan, Deborah A, Swiatecka-Urban, Agnieszka, Stanton, Bruce A, O'Toole, George A

“…We previously reported that Pseudomonas aeruginosa PA14 secretes a protein that can reduce the apical membrane expression of the cystic fibrosis transmembrane…”
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Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase by Albiston, Anthony L, Morton, Craig J, Ng, Hooi Ling, Pham, Vi, Yeatman, Holly R, Ye, Siying, Fernando, Ruani N, De Bundel, Dimitri, Ascher, David B, Mendelsohn, Frederick A.O, Parker, Michael W, Chai, Siew Yeen

“…Approximately one-quarter of people over the age of 65 are estimated to suffer some form of cognitive impairment, underscoring the need for effective…”
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Influenza reverse genetics: dissecting immunity and pathogenesis by Ye, Siying, Evans, Justin G, Stambas, John

“…Reverse genetics systems allow artificial generation of non-segmented and segmented negative-sense RNA viruses, like influenza viruses, entirely from cloned…”
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Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP) by Lew, Rebecca A., Mustafa, Tomris, Ye, Siying, McDowall, Sharon G., Chai, Siew Yeen, Albiston, Anthony L.

“…Angiotensin IV (Ang IV) exerts profound effects on memory and learning, a phenomenon ascribed to its binding to a specific AT4 receptor. However the AT4…”
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Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase by Albiston, Anthony L, Pham, Vi, Ye, Siying, Ng, Leelee, Lew, Rebecca A, Thompson, Philip E, Holien, Jessica K, Morton, Craig J, Parker, Michael W, Chai, Siew Yeen

“…Inhibitors of insulin-regulated aminopeptidase (IRAP) improve memory and are being developed as a novel treatment for memory loss. In this study, the binding…”
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A critical role for the short intracellular C terminus in receptor activity-modifying protein function by Udawela, Madhara, Christopoulos, George, Morfis, Maria, Christopoulos, Arthur, Ye, Siying, Tilakaratne, Nanda, Sexton, Patrick M

“…Receptor activity-modifying proteins (RAMPs) interact with and modify the behavior of the calcitonin receptor (CTR) and calcitonin receptor-like receptor…”
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Membrane bound members of the M1 family: more than aminopeptidases by Albiston, Anthony L, Ye, Siying, Chai, Siew Yeen

“…In mammals the M1 aminopeptidase family consists of nine different proteins, five of which are integral membrane proteins. The aminopeptidases are defined by…”
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Alzheimer's, Angiotensin IV and an Aminopeptidase by Albiston, Anthony Lloyd, Fernando, Ruani, Ye, Siying, Peck, Grantley Ross, Chai, Siew Yeen

“…The angiotensin AT4 receptor was originally defined as the specific, high affinity binding site for the hexapeptide angiotensin IV (Ang IV). Subsequently, the…”
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Gel properties transition from mono-succinylation to cross-linking of agar by attemperation with succinic anhydride by Xiao, Qiong, Ye, Siying, Zhang, Yonghui, Chen, Jun, Chen, Fuquan, Weng, Huifen, Xiao, Anfeng

“…[Display omitted] •The transition from succinylation to crosslink of agar was achieved by attemperation.•Agar succinylation greatly improved its swelling ratio…”
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Synthesis and properties of maleic anhydride-modified agar with reversibly controlled gel strength by Ye, Siying, Zhang, Yonghui, Chen, Jun, Chen, Fuquan, Weng, Huifen, Xiao, Qiong, Xiao, Anfeng

“…[Display omitted] Agar is modified by chemical methods to improve its functional properties and meet the increasing demand of the market. Some of the…”
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Super absorbent glutaric anhydride-modified agar: Structure, properties, and application in biomaterial delivery by Zhang, Luyao, Ye, Siying, Chen, Fuquan, Xiao, Qiong, Weng, Huifen, Xiao, Anfeng

“…Agar was modified with glutaric anhydride (GA) in this study to expand its application in food and medicine. Glutaric anhydride-modified agar (GAR) can…”
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Colorimetric aptasensor based on magnetic beads and gold nanoparticles for detecting mucin 1 by Ye, Siying, Wu, Xiaoyan, Chen, Huilong, Chen, Shuping, Zeng, Yingying, Zhang, Hongyan, Yu, Yuyan

“…[Display omitted] •A visual detection method for mucin 1 has been developed.•The system combines advantages of aptamer, magnetic beads, and gold…”
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Alzheimer's, Angiotensin IV and an Aminopeptidase by Anthony Lloyd ALBISTON, Ruani FERNANDO, Siying YE, Grantley Ross PECK, Siew Yeen CHAI

“…The angiotensin AT4 receptor was originally defined as the specific, high affinity binding site for the hexapeptide angiotensin IV (Ang IV). Subsequently, the…”
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