Search Results - "Ye, Qiaozhen"
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The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein
Published in Nature communications (21-01-2021)“…The multifunctional nucleocapsid (N) protein in SARS-CoV-2 binds the ~30 kb viral RNA genome to aid its packaging into the 80–90 nm membrane-enveloped virion…”
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Architecture and self‐assembly of the SARS‐CoV‐2 nucleocapsid protein
Published in Protein science (01-09-2020)“…The COVID‐2019 pandemic is the most severe acute public health threat of the twenty‐first century. To properly address this crisis with both robust testing and…”
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Structural Basis for SARS-CoV-2 Nucleocapsid Protein Recognition by Single-Domain Antibodies
Published in Frontiers in immunology (26-07-2021)“…The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, is the most severe public health event of the twenty-first century. While effective vaccines…”
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TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching
Published in eLife (28-04-2015)“…The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved…”
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A conserved filamentous assembly underlies the structure of the meiotic chromosome axis
Published in eLife (18-01-2019)“…The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are…”
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The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA
Published in Nature (21-12-2006)“…Influenza A viruses pose a serious threat to world public health, particularly the currently circulating avian H5N1 viruses. The influenza viral nucleoprotein…”
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Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition
Published in Nature cell biology (01-09-2022)“…While acetylated, RNA-binding-deficient TDP-43 reversibly phase separates within nuclei into complex droplets (anisosomes) comprised of TDP-43-containing…”
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TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC
Published in Nature communications (19-10-2018)“…The mitotic checkpoint ensures accurate chromosome segregation through assembly of the mitotic checkpoint complex (MCC), a soluble inhibitor of the…”
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Structure of the hepatitis E virus-like particle suggests mechanisms for virus assembly and receptor binding
Published in Proceedings of the National Academy of Sciences - PNAS (04-08-2009)“…Hepatitis E virus (HEV), a small, non-enveloped RNA virus in the family Hepeviridae, is associated with endemic and epidemic acute viral hepatitis in…”
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10
Sister kinetochores are mechanically fused during meiosis I in yeast
Published in Science (American Association for the Advancement of Science) (10-10-2014)“…Production of healthy gametes requires a reductional meiosis I division in which replicated sister chromatids comigrate, rather than separate as in mitosis or…”
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Sequence in the Influenza A Virus Nucleoprotein Required for Viral Polymerase Binding and RNA Synthesis
Published in Journal of Virology (01-07-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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RNA virus replication complexes
Published in PLoS pathogens (01-07-2010)“… In picornavirus-infected cells, viral RNA replication occurs on the cytoplasmic surfaces of double-membrane vesicles derived from the endoplasmic reticulum…”
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Interaction of the Influenza A Virus Nucleocapsid Protein with the Viral RNA Polymerase Potentiates Unprimed Viral RNA Replication
Published in Journal of Virology (01-01-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Biochemical and structural evidence in support of a coherent model for the formation of the double-helical influenza A virus ribonucleoprotein
Published in mBio (01-03-2013)“…Influenza A virions contain eight ribonucleoproteins (RNPs), each comprised of a negative-strand viral RNA, the viral polymerase, and multiple nucleoproteins…”
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In Situ imaging of orthotopic kidney cancer in the murine model using an aminopeptidase N activatable fluorescent probe
Published in Sensors and actuators. B, Chemical (15-11-2023)“…Surgical treatment is the most effective treatment for renal cancer. It is urgent to develop highly selective and sensitive analytical methods for specially…”
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Reaction-Activated Disassembly of the NIR-II Probe Enables Fast Detection and Ratiometric Photoacoustic Imaging of Glutathione In Vivo
Published in Analytical chemistry (Washington) (19-09-2023)“…Glutathione (GSH), the most abundant nonprotein biothiol, is a significant endogenous molecule that plays a key role in redox equilibrium in vivo and is…”
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Engineering of a low intrinsic fluorescence and chemical-stable fluorescent probe enables highly sensitive detection of biothiols and high-fidelity imaging of dihydroartemisinin-induced ferroptosis
Published in Sensors and actuators. B, Chemical (01-02-2025)“…Ferroptosis modulation represents a novel therapeutic strategy for pancreatic ductal adenocarcinoma (PDAC), where precise control of ferroptotic levels is…”
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β-galactosidase activatable chemiluminescent probe for in vivo imaging and point-of care test
Published in Sensors and actuators. B, Chemical (01-12-2023)“…As a highly effective tool with a superior signal-to-noise ratio, chemiluminescent probes find extensive utility in the in vivo detection of diverse…”
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Recent progress of molecular fluorescent probes with multi-recognition sites enable sensitive and selective analysis
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-05-2024)“…Reaction-based fluorescent probes can react with the target through one-step reaction induced by the collision between the analytes and the probes, and…”
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A Quencher‐Based Blood‐Autofluorescence‐Suppression Strategy Enables the Quantification of Trace Analytes in Whole Blood
Published in Angewandte Chemie International Edition (19-06-2023)“…Precise quantification of trace components in whole blood via fluorescence is of great significance. However, the applicability of current fluorescent probes…”
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