Search Results - "Ye, Peizhen"
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Evaluation of [18F]F-TZ3108 for PET Imaging of Metabolic-Associated Fatty Liver Disease
Published in Molecular imaging and biology (01-12-2022)“…Purpose Sigma-1 receptor (Sig-1R), a chaperone that resides at the mitochondrion-associated endoplasmic reticulum (ER) membrane, is an ER stress biomarker. It…”
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Synthesis and Evaluation of [64Cu]Cu-NOTA-HFn for PET Imaging of Transferrin Receptor 1 Expression in Nasopharyngeal Carcinoma
Published in ACS omega (16-04-2024)“…As recurrent and metastatic nasopharyngeal carcinoma (NPC) is the most common cause of death among patients with NPC, there is an urgent clinical need for the…”
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Positron emission tomography imaging of the P2X7 receptor with a novel tracer, [18F]GSK1482160, in a transgenic mouse model of Alzheimer's disease and healthy non‐human primates
Published in Brain-X (01-03-2024)“…This study aimed to evaluate [18F]GSK1482160 Positron emission tomography imaging for targeting P2X7R, a biomarker for neuroinflammation. Studies of acute…”
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Detoxification of benzo[a]pyrene primarily depends on cytochrome P450, while bioactivation involves additional oxidoreductases including 5‐lipoxygenase, cyclooxygenase, and aldo‐keto reductase in the liver
Published in Journal of biochemical and molecular toxicology (01-07-2017)“…Cytochrome P450s are involved in detoxification and activation of benzo[a]pyrene (BaP) with unclear balance and unknown contribution of other oxidoreductases…”
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Hetero-aryl bromide precursor fluorine-18 radiosynthesis and preclinical evaluation of a novel positron emission tomography (PET) tracer [18F]GSK1482160
Published in Bioorganic & medicinal chemistry (01-11-2022)“…[Display omitted] The purinergic P2X7 receptor (P2X7R), an ATP gated ion channel, is an important therapeutic target for various inflammatory immune and…”
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In Vivo Detection of Lymph Nodes Metastasis of ESCC Using CXCR4-Targeted Tracer [64Cu]Cu-NOTA-CP01
Published in Molecular imaging and biology (04-11-2024)Get full text
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Effectiveness of electro-acupuncture for cognitive improvement on Alzheimer's disease quantified via PET imaging of sphingosine-1-phosphate receptor 1
Published in Alzheimer's & dementia (25-09-2024)“…Electro-acupuncture (EA) has demonstrated potential in improving mild-to-moderate dementia in clinics, but the underlying scientific target remains unclear. EA…”
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Activated Microglia in the Early Stage of a Rat Model of Parkinson’s Disease: Revealed by PET-MRI Imaging by [18F]DPA-714 Targeting TSPO
Published in ACS chemical neuroscience (07-06-2023)“…In the past decades, translocator protein (TSPO) has been considered as an in vivo biomarker to measure the presence of neuroinflammatory reactions. In this…”
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PET Imaging of P2X7 Receptor (P2X7R) for Neuroinflammation with Improved Radiosynthesis of Tracer [ 18 F]4A in Mice and Non-human Primates
Published in ACS chemical neuroscience (07-12-2022)“…The P2X7 receptor (P2X7R) is a key neuroinflammation target in a variety of neurodegenerative diseases. Improved radiosynthesis was developed according to the…”
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In Vivo Detection of Lymph Nodes Metastasis of ESCC Using CXCR4-Targeted Tracer 64CuCu-NOTA-CP01
Published in Molecular imaging and biology (04-11-2024)“…Esophageal squamous cell carcinoma (ESCC) frequently exhibits skip metastasis to lymph nodes; however, non-invasive imaging techniques capable of directly…”
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Preclinical evaluation of the mono-PEGylated recombinant human interleukin-11 in cynomolgus monkeys
Published in Toxicology and applied pharmacology (01-03-2018)“…The mono-PEGylated recombinant human interleukin-11 (rhIL-11) was evaluated for its pharmacology and toxicology profile in non-human primates. This PEGylated…”
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