Search Results - "Ye, Mujie"

m6A Modification: A Double-Edged Sword in Tumor Development by Gao, Runnan, Ye, Mujie, Liu, Baihui, Wei, Meng, Ma, Duan, Dong, Kuiran

“…Modification of m6A, as the most abundant mRNA modification, plays diverse roles in various biological processes in eukaryotes. Emerging evidence has revealed…”
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Emerging role of long noncoding RNA-encoded micropeptides in cancer by Ye, Mujie, Zhang, Jingjing, Wei, Meng, Liu, Baihui, Dong, Kuiran

“…Abstract Increasing evidence has indicated that long noncoding RNAs (lncRNAs) play various important roles in the development of cancers. The widespread…”
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Downregulation of MEG3 and upregulation of EZH2 cooperatively promote neuroblastoma progression by Ye, Mujie, Gao, Runnan, Chen, Shiyu, Wei, Meng, Wang, Jing, Zhang, Bowen, Wu, Suwen, Xu, Yuexin, Wu, Peixuan, Chen, Xin, Ma, Jing, Ma, Duan, Dong, Kuiran

“…Neuroblastoma (NB), an embryonic tumour originating from sympathetic crest cells, is the most common extracranial solid tumour type in children with poor…”
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ALKBH5 enhances lipid metabolism reprogramming by increasing stability of FABP5 to promote pancreatic neuroendocrine neoplasms progression in an m6A-IGF2BP2-dependent manner by Chen, Jinhao, Ye, Mujie, Bai, Jianan, Gong, Zhihui, Yan, Lijun, Gu, Danyang, Hu, Chunhua, Lu, Feiyu, Yu, Ping, Xu, Lin, Wang, Yan, Tian, Ye, Tang, Qiyun

“…Abstract The process of post-transcriptional regulation has been recognized to be significantly impacted by the presence of N 6-methyladenosine (m6A)…”
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Hypoxia upregulating ACSS2 enhances lipid metabolism reprogramming through HMGCS1 mediated PI3K/AKT/mTOR pathway to promote the progression of pancreatic neuroendocrine neoplasms by Gu, Danyang, Ye, Mujie, Zhu, Guoqin, Bai, Jianan, Chen, Jinhao, Yan, Lijun, Yu, Ping, Lu, Feiyu, Hu, Chunhua, Zhong, Yuan, Liu, Pengfei, He, Qibin, Tang, Qiyun

“…Pancreatic neuroendocrine neoplasms (pNENs) are relatively rare. Hypoxia and lipid metabolism-related gene acetyl-CoA synthetase 2 (ACSS2) is involved in tumor…”
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Methylmalonic acid promotes colorectal cancer progression via activation of Wnt/β-catenin pathway mediated epithelial-mesenchymal transition by Hu, Chunhua, Ye, Mujie, Bai, Jianan, Liu, Pengfei, Lu, Feiyu, Chen, Jinhao, Yu, Ping, Chen, Tiaotiao, Shi, Xiaoting, Tang, Qiyun

“…It has been manifested in several studies that age-related metabolic reprogramming is associated with tumor progression, in particular, colorectal cancer…”
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Down-regulated FTO and ALKBH5 co-operatively activates FOXO signaling through m6A methylation modification in HK2 mRNA mediated by IGF2BP2 to enhance glycolysis in colorectal cancer by Ye, Mujie, Chen, Jinhao, Lu, Feiyu, Zhao, Minghui, Wu, Suwen, Hu, Chunhua, Yu, Ping, Kan, Jingbao, Bai, Jianan, Tian, Ye, Tang, Qiyun

“…N6-methyladenosine (m6A) modification is the most abundant reversible methylation modification in eukaryotes, and it is reportedly closely associated with a…”
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FAM201A encodes small protein NBASP to inhibit neuroblastoma progression via inactivating MAPK pathway mediated by FABP5 by Ye, Mujie, Gao, Runnan, Chen, Shiyu, Bai, Jianan, Chen, Jinhao, Lu, Feiyu, Gu, Danyang, Shi, Xiaoting, Yu, Ping, Tian, Ye, Tang, Qiyun, Dong, Kuiran

“…Increasing evidence indicates that long non-coding RNA (lncRNA) is one of the most important RNA regulators in the pathogenesis of neuroblastoma (NB). Here, we…”
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S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression by He, Weijing, Zhang, Jingjing, Liu, Baihui, Liu, Xiangqi, Liu, Gongbao, Xie, Lulu, He, Jiajun, Wei, Meng, Li, Kai, Ma, Jing, Dong, Rui, Ma, Duan, Dong, Kuiran, Ye, Mujie

“…A previous study on hepatoblastoma revealed novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex, including the tumor suppressor…”
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SP1-Mediated Upregulation of Long Noncoding RNA ZFAS1 Involved in Non-syndromic Cleft Lip and Palate via Inactivating WNT/β-Catenin Signaling Pathway by Chen, Shiyu, Jia, Zhonglin, Cai, Ming, Ye, Mujie, Wu, Dandan, Wan, Teng, Zhang, Bowen, Wu, Peixuan, Xu, Yuexin, Guo, Yuntao, Tian, Chan, Ma, Duan, Ma, Jing

“…Non-syndromic cleft lip and palate (NSCLP) is one of the most common congenital malformations with multifactorial etiology. Although long non-coding RNAs…”
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FABP5 regulates lipid metabolism to facilitate pancreatic neuroendocrine neoplasms progression via FASN mediated Wnt/β‐catenin pathway by Lu, Feiyu, Ye, Mujie, Hu, Chunhua, Chen, Jinhao, Yan, Lijun, Gu, Danyang, Xu, Lin, Tian, Ye, Bai, Jianan, Tang, Qiyun

“…Pancreatic neuroendocrine neoplasms (pNENs) are among the most frequently occurring neuroendocrine neoplasms (NENs) and require targeted therapy. High levels…”
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Novel insights into the interplay between m6A modification and programmed cell death in cancer by Chen, Jinhao, Ye, Mujie, Bai, Jianan, Hu, Chunhua, Lu, Feiyu, Gu, Danyang, Yu, Ping, Tang, Qiyun

“…N6-methyladenosine (m6A) methylation, the most prevalent and abundant RNA modification in eukaryotes, has recently become a hot research topic. Several studies…”
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Circulating tumor DNA in neuroblastoma by Wei, Meng, Ye, Mujie, Dong, Kuiran, Dong, Rui

“…As a sympathetic nervous system–derived tumor, aggressive neuroblastoma (NB) is currently attracting interest from researchers seeking diagnostic and…”
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FOXA2-initiated transcriptional activation of INHBA induced by methylmalonic acid promotes pancreatic neuroendocrine neoplasm progression by Hu, Chunhua, Ye, Mujie, Bai, Jianan, Liu, Pengfei, Lu, Feiyu, Chen, Jinhao, Xu, Yanling, Yan, Lijun, Yu, Ping, Xiao, Zequan, Gu, Danyang, Xu, Lin, Tian, Ye, Tang, Qiyun

“…Pancreatic neuroendocrine neoplasms (PanNENs) are a group of highly heterogeneous neoplasms originating from the endocrine islet cells of the pancreas with…”
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Multifunctional cascade nanocatalysts for NIR-II-synergized photonic hyperthermia-strengthened nanocatalytic therapy of epithelial and embryonal tumors by Liu, Xiangqi, Feng, Wei, Xiang, Huijing, Liu, Baihui, Ye, Mujie, Wei, Meng, Dong, Rui, Chen, Yu, Dong, Kuiran

“…•Innovation of multifunctional nanocatalysts against epithelial and embryonal tumors.•Synergistic nanotherapy triggered by tumor microenvironment and NIR-II…”
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WTAP activates MAPK signaling through m6A methylation in VEGFA mRNA‐mediated by YTHDC1 to promote colorectal cancer development by Ye, Mujie, Chen, Jinhao, Yu, Ping, Hu, Chunhua, Wang, Bangting, Bao, Jinxing, Lu, Feiyu, Zhong, Yuan, Yan, Lijun, Kan, Jingbao, Bai, Jianan, Tian, Ye, Tang, Qiyun

“…N6‐methyladenosine modification, especially Wilms tumor 1‐associated protein (WTAP), is reportedly associated with a variety of cancers, including colorectal…”
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Hypoxia exosome derived CEACAM5 promotes tumor‐associated macrophages M2 polarization to accelerate pancreatic neuroendocrine tumors metastasis via MMP9 by Ye, Mujie, Lu, Feiyu, Gu, Danyang, Xue, Bingyan, Xu, Lin, Hu, Chuanhua, Chen, Jinhao, Yu, Ping, Zheng, Hongxia, Gao, Yue, Wang, Jianhua, Tang, Qiyun

“…Exosomes play significant roles in the communications between tumor cells and tumor microenvironment. However, the specific mechanisms by which exosomes…”
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Identification of EGR4 as a prospective target for inhibiting tumor cell proliferation and a novel biomarker in colorectal cancer by Wang, Bangting, Zhang, Shijie, Wang, Haiyang, Wang, Min, Tao, Yuwen, Ye, Mujie, Fan, Zhining, Wang, Yan, Liu, Li

“…EGR4 (Early Growth Response 4) is a member of the EGR family, involving in tumorigenesis. However, the function and action mechanism of EGR4 in the…”
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Linc01105 acts as an oncogene in the development of neuroblastoma by Ye, Mujie, Ma, Jing, Liu, Baihui, Liu, Xiangqi, Ma, Duan, Dong, Kuiran

“…Previous research from our group revealed that the long coding RNA (lncRNA) linc01105 is associated with neuroblastoma proliferation and apoptosis, and that…”
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FABP5 suppresses colorectal cancer progression via mTOR-mediated autophagy by decreasing FASN expression by Ye, Mujie, Hu, Chunhua, Chen, Tiaotiao, Yu, Ping, Chen, Jinhao, Lu, Feiyu, Xu, Lin, Zhong, Yuan, Yan, Lijun, Kan, Jingbao, Bai, Jianan, Li, Xiaolin, Tian, Ye, Tang, Qiyun

“…Lipid metabolism plays an important role in the occurrence and development of cancer, in particular, digestive system tumors such as colon cancer. Here, we…”
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