Search Results - "Ye, Mingzhou"

A Tumor‐Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers by Ye, Mingzhou, Han, Yuxin, Tang, Jianbin, Piao, Ying, Liu, Xiangrui, Zhou, Zhuxian, Gao, Jianqing, Rao, Jianghong, Shen, Youqing

“…A cascade amplification release nanoparticle (CARN) is constructed by the coencapsulation of β‐lapachone and a reactive‐oxygen‐species (ROS)‐responsive…”
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Enhancing the In Vitro and In Vivo Stabilities of Polymeric Nucleic Acid Delivery Nanosystems by Wang, Yuyuan, Ye, Mingzhou, Xie, Ruosen, Gong, Shaoqin

“…Gene therapy holds great promise for various medical and biomedical applications. Nonviral gene delivery systems formed by cationic polymer and nucleic acids…”
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Zinc phthalocyanine encapsulated in polymer micelles as a potent photosensitizer for the photodynamic therapy of osteosarcoma by Yu, Wei, Ye, Mingzhou, Zhu, Jian, Wang, Yitian, Liang, Chengzhen, Tang, Jianbin, Tao, Huimin, Shen, Youqing

“…Zinc phthalocyanine (ZnPc) is a highly potent second-generation photosensitizer for cancer photodynamic therapy (PDT) with attractive photo-physical and…”
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Multifunctional nanoparticle potentiates the in situ vaccination effect of radiation therapy and enhances response to immune checkpoint blockade by Zhang, Ying, Sriramaneni, Raghava N., Clark, Paul A., Jagodinsky, Justin C., Ye, Mingzhou, Jin, Wonjong, Wang, Yuyuan, Bates, Amber, Kerr, Caroline P., Le, Trang, Allawi, Raad, Wang, Xiuxiu, Xie, Ruosen, Havighurst, Thomas C., Chakravarty, Ishan, Rakhmilevich, Alexander L., O’Leary, Kathleen A., Schuler, Linda A., Sondel, Paul M., Kim, Kyungmann, Gong, Shaoqin, Morris, Zachary S.

“…Radiation therapy (RT) activates an in situ vaccine effect when combined with immune checkpoint blockade (ICB), yet this effect may be limited because RT does…”
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Targeted PERK inhibition with biomimetic nanoclusters confers preventative and interventional benefits to elastase-induced abdominal aortic aneurysms by Yodsanit, Nisakorn, Shirasu, Takuro, Huang, Yitao, Yin, Li, Islam, Zain Husain, Gregg, Alexander Christopher, Riccio, Alessandra Marie, Tang, Runze, Kent, Eric William, Wang, Yuyuan, Xie, Ruosen, Zhao, Yi, Ye, Mingzhou, Zhu, Jingcheng, Huang, Yi, Hoyt, Nicholas, Zhang, Mengxue, Hossack, John A., Salmon, Morgan, Kent, K. Craig, Guo, Lian-Wang, Gong, Shaoqin, Wang, Bowen

“…Abdominal aortic aneurysm (AAA) is a progressive aortic dilatation, causing ∼80% mortality upon rupture. Currently, there is no approved drug therapy for AAA…”
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A Dual‐Responsive Antibiotic‐Loaded Nanoparticle Specifically Binds Pathogens and Overcomes Antimicrobial‐Resistant Infections by Ye, Mingzhou, Zhao, Yi, Wang, Yuyuan, Zhao, Miao, Yodsanit, Nisakorn, Xie, Ruosen, Andes, David, Gong, Shaoqin

“…Antimicrobial resistant (AMR) infections are a growing threat to public health and there is a general lack of development in new antibiotics. Here, a…”
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pH‐Responsive Polymer–Drug Conjugate: An Effective Strategy to Combat the Antimicrobial Resistance by Ye, Mingzhou, Zhao, Yi, Wang, Yuyuan, Yodsanit, Nisakorn, Xie, Ruosen, Gong, Shaoqin

“…An urgent need for developing new antimicrobial approaches has emerged due to the imminent threat of antimicrobial‐resistant (AMR) pathogens. Bacterial…”
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Biomimetic fibrin-targeted and H2O2-responsive nanocarriers for thrombus therapy by Zhao, Yi, Xie, Ruosen, Yodsanit, Nisakorn, Ye, Mingzhou, Wang, Yuyuan, Gong, Shaoqin

“…[Display omitted] •H2O2-responsive thrombus-targeting RBC membrane-cloaked prodrug nanoparticles (T-RBC-DTC NPs) for antithrombotic therapy.•The T-RBC-DTC NPs…”
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NAD(H)-loaded nanoparticles for efficient sepsis therapy via modulating immune and vascular homeostasis by Ye, Mingzhou, Zhao, Yi, Wang, Yuyuan, Xie, Ruosen, Tong, Yao, Sauer, John-Demian, Gong, Shaoqin

“…Sepsis is a life-threatening organ dysfunction responsible for nearly 270,000 deaths annually in the United States alone. Nicotinamide adenine dinucleotide…”
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pH‐Responsive Polymer Nanoparticles for Efficient Delivery of Cas9 Ribonucleoprotein With or Without Donor DNA by Xie, Ruosen, Wang, Xiuxiu, Wang, Yuyuan, Ye, Mingzhou, Zhao, Yi, Yandell, Brian S., Gong, Shaoqin

“…Clustered regularly interspaced short palindromic repeat (CRISPR)‐associated protein 9 (Cas9) may offer new therapeutics for genetic diseases through gene…”
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Dual-channel NIR activatable theranostic prodrug for in vivo spatiotemporal tracking thiol-triggered chemotherapy by Ye, Mingzhou, Wang, Xiaohang, Tang, Jianbin, Guo, Zhiqian, Shen, Youqing, Tian, He, Zhu, Wei-Hong

“…Real-time tracking for where (W), when (W), and how (H) prodrugs are delivered and activated is a great challenge for prodrug development. Disulfide…”
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Development of an In Situ Cancer Vaccine via Combinational Radiation and Bacterial‐Membrane‐Coated Nanoparticles by Patel, Ravi B., Ye, Mingzhou, Carlson, Peter M., Jaquish, Abigail, Zangl, Luke, Ma, Ben, Wang, Yuyuan, Arthur, Ian, Xie, Ruosen, Brown, Ryan J., Wang, Xing, Sriramaneni, Raghava, Kim, KyungMann, Gong, Shaoqin, Morris, Zachary S.

“…Neoantigens induced by random mutations and specific to an individual's cancer are the most important tumor antigens recognized by T cells. Among…”
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Research progress on the nucleoside/nucleotide-loaded nanomedicines by Zhou, Zheng, Liu, Haifang, Ye, Mingzhou

“…Nucleoside drugs play an essential role in treating major diseases such as tumor and viral infections, and have been widely applied in clinics. However, the…”
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Multimodal nanoimmunotherapy engages neutrophils to eliminate Staphylococcus aureus infections by Zhu, Jingcheng, Xie, Ruosen, Gao, Ruixuan, Zhao, Yi, Yodsanit, Nisakorn, Zhu, Min, Burger, Jacobus C., Ye, Mingzhou, Tong, Yao, Gong, Shaoqin

“…The increasing prevalence of antimicrobial resistance in Staphylococcus aureus necessitates alternative therapeutic approaches. Neutrophils play a crucial role…”
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Ultrasound-activable piezoelectric membranes for accelerating wound healing by Shi, Xingxing, Chen, Yingxin, Zhao, Yi, Ye, Mingzhou, Zhang, Shuidong, Gong, Shaoqin

“…Ultrasonic energy harvesting technologies have gained much attention for biomedical applications due to their several desirable features including low-energy…”
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Targeted biodegradable dendritic MRI contrast agent for enhanced tumor imaging by Ye, Mingzhou, Qian, Yue, Tang, Jianbin, Hu, Hongjie, Sui, Meihua, Shen, Youqing

“…Highly sensitive and safe contrast agents (CAs) are essential for magnetic resonance imaging (MRI) to achieve accurate tumor detection and imaging…”
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Double-Network Nanogel as a Nonviral Vector for DNA Delivery by Ye, Mingzhou, Wang, Yuyuan, Zhao, Yi, Xie, Ruosen, Yodsanit, Nisakorn, Johnston, Kadina, Gong, Shaoqin

“…A double-network nanogel, composed of a silane-cross-linked polyethylenimine (PEI) network (i.e., PEI-S) and a pH-responsive poly­(2-(hexamethyleneimino) ethyl…”
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Biomimetic, ROS-detonable nanoclusters — A multimodal nanoplatform for anti-restenotic therapy by Zhao, Yi, Shirasu, Takuro, Yodsanit, Nisakorn, Kent, Eric, Ye, Mingzhou, Wang, Yuyuan, Xie, Ruosen, Gregg, Alexander Christopher, Huang, Yitao, Kent, K. Craig, Guo, Lian-Wang, Gong, Shaoqin, Wang, Bowen

“…The long-term success of endovascular intervention has long been overshadowed by vessel re-occlusion, also known as restenosis. Mainstream anti-restenotic…”
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Biomimetic fibrin-targeted and H 2 O 2 -responsive nanocarriers for thrombus therapy by Zhao, Yi, Xie, Ruosen, Yodsanit, Nisakorn, Ye, Mingzhou, Wang, Yuyuan, Gong, Shaoqin

“…Thrombosis is a principle cause of various life-threatening cardiovascular diseases. However, current antithrombotic treatments using drugs only offer limited…”
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A porphyrin-based magnetic and fluorescent dual-modal nanoprobe for tumor imaging by Hu, Hongjie, Sheng, Yuqi, Ye, Mingzhou, Qian, Yue, Tang, Jianbin, Shen, Youqing

“…The combination of magnetic resonance imaging (MRI) and fluorescent imaging with a dual-modal probe could exert the advantages of the two imaging techniques,…”
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