Search Results - "Ye, Leiguang"
-
1
Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy
Published in Cancer cell (12-08-2019)“…Reactivation of T cell immunity by PD-1/PD-L1 immune checkpoint blockade has been shown to be a promising cancer therapeutic strategy. However, PD-L1…”
Get full text
Journal Article -
2
SASH1 suppresses triple-negative breast cancer cell invasion through YAP-ARHGAP42-actin axis
Published in Oncogene (02-07-2020)“…Triple-negative breast cancer (TNBC) is extremely aggressive and lacks effective therapy. SAM and SH3 domain containing1 (SASH1) has been implicated in TNBC as…”
Get full text
Journal Article -
3
Combining Immune-Related Genes For Delineating the Extracellular Matrix and Predicting Hormone Therapy and Neoadjuvant Chemotherapy Benefits In Breast Cancer
Published in Frontiers in immunology (14-07-2022)“…Breast cancer (BC) is the most prevalent cancer in women worldwide. A systematic approach to BC treatment, comprising adjuvant and neoadjuvant chemotherapy…”
Get full text
Journal Article -
4
Study of circulating IgG antibodies to BIRC5 and MYC in non-small cell lung cancer
Published in FEBS open bio (01-01-2015)“…•An in-house ELISA was developed to detect circulating antibodies to peptide antigens.•Circulating anti-MYC IgG levels were significantly increased in patients…”
Get full text
Journal Article -
5
Exosomes-regulated lipid metabolism in tumorigenesis and cancer progression
Published in Cytokine & growth factor reviews (01-10-2023)“…Increasing evidence highlights the role of lipid metabolism in tumorigenesis and tumor progression. Targeting the processes of lipid metabolism, including…”
Get full text
Journal Article -
6
-
7
miR-211 promotes non-small cell lung cancer proliferation by targeting SRCIN1
Published in Tumor biology (2016)“…MicroRNAs (miRNAs) are a class of small non-coding RNAs that, when dysregulated, are involved in the initiation and progression of various cancers, including…”
Get full text
Journal Article -
8
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer
Published in Breast cancer research and treatment (01-10-2023)“…Background Breast cancer (BC) is regarded as one of the most common cancers diagnosed among the female population and has an extremely high mortality rate. It…”
Get full text
Journal Article -
9
-
10
Clinical Manifestation, Risk Factors, and Immune Checkpoint Inhibitor Rechallenge of Checkpoint Inhibitor-Associated Pneumonitis in Patients With Lung Cancer
Published in Journal of immunotherapy (1997) (01-07-2024)“…Immune-related adverse effects can lead to damage to various systems of the body, checkpoint inhibitor-associated pneumonitis (CIP) is one of the potentially…”
Get full text
Journal Article -
11
MiR-210 in exosomes derived from CAFs promotes non-small cell lung cancer migration and invasion through PTEN/PI3K/AKT pathway
Published in Cellular signalling (01-09-2020)“…Cancer-associated fibroblasts (CAFs) function as a crucial factor in tumor progression by carrying exosomes to neighboring cells. This study was assigned to…”
Get full text
Journal Article -
12
Nucleus-exported CLOCK acetylates PRPS to promote de novo nucleotide synthesis and liver tumour growth
Published in Nature cell biology (01-02-2023)“…Impairment of the circadian clock is linked to cancer development. However, whether the circadian clock is modulated by oncogenic receptor tyrosine kinases…”
Get full text
Journal Article -
13
VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation
Published in The EMBO journal (15-03-2024)“…The Von Hippel–Lindau (VHL) protein, which is frequently mutated in clear-cell renal cell carcinoma (ccRCC), is a master regulator of hypoxia-inducible factor…”
Get full text
Journal Article -
14
MicroRNA-590-3p inhibits invasion and metastasis in triple-negative breast cancer by targeting Slug
Published in American journal of cancer research (01-01-2020)“…miR-590-3p acts as a tumor suppressor in glioblastoma multiform, medulloblastoma, hepatocellular carcinoma, and nephroblastoma. Here, we studied the role of…”
Get full text
Journal Article -
15
Immunopontentiating and antitumor activities of a polysaccharide from Pulsatilla chinensis (Bunge) Regel
Published in International journal of biological macromolecules (01-03-2013)“…► Polysaccharide PCPw from Pulsatilla chinensis have been first fractionated. ► PCPw was composed of rhamnose, arabinose, xylose, galactose and mannose. ► PCPw…”
Get full text
Journal Article -
16
Circulating autoantibody to FOXP3 may be a potential biomarker for esophageal squamous cell carcinoma
Published in Tumor biology (01-06-2013)“…The present study was undertaken to develop a relatively quantitative enzyme-linked immunosorbent assay (ELISA) in-house using human leukocyte antigen class…”
Get full text
Journal Article -
17
Chinese expert consensus on the diagnosis and treatment of thymic epithelial tumors
Published in Thoracic cancer (01-04-2023)“…Thymic epithelial tumors (TETs) are a relatively rare type of thoracic tumor, accounting for less than 1% of all tumors. The incidence of TETs is about…”
Get full text
Journal Article -
18
Autoantibodies against p16 protein-derived peptides may be a potential biomarker for non-small cell lung cancer
Published in Tumor biology (01-03-2014)“…Overexpression of tumor-associated antigens (TAAs) has been reported in many types of cancer and may trigger secretion of their autoantibodies. The present…”
Get full text
Journal Article -
19
Chinese expert consensus on the diagnosis and treatment of malignant pleural mesothelioma
Published in Thoracic cancer (01-09-2023)“…Malignant pleural mesothelioma (MPM) is a malignant tumor originating from the pleura, and its incidence has been increasing in recent years. Due to the…”
Get full text
Journal Article