Search Results - "Ye, Dingwei"

Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer by Chi, Kim N, Agarwal, Neeraj, Bjartell, Anders, Chung, Byung Ha, Pereira de Santana Gomes, Andrea J, Given, Robert, Juárez Soto, Álvaro, Merseburger, Axel S, Özgüroğlu, Mustafa, Uemura, Hirotsugu, Ye, Dingwei, Deprince, Kris, Naini, Vahid, Li, Jinhui, Cheng, Shinta, Yu, Margaret K, Zhang, Ke, Larsen, Julie S, McCarthy, Sharon, Chowdhury, Simon

“…A randomized trial tested whether the addition of apalutamide, an androgen receptor blocker, to androgen-deprivation therapy might improve radiographic…”
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LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer by Luo, Wenjie, Wang, Jun, Xu, Wenhao, Ma, Chunguang, Wan, Fangning, Huang, Yongqiang, Yao, Mengfei, Zhang, Hailiang, Qu, Yuanyuan, Ye, Dingwei, Zhu, Yiping

“…Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and development in bladder cancer. However, the underlying molecular mechanisms…”
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Epidemiology and genomics of prostate cancer in Asian men by Zhu, Yao, Mo, Miao, Wei, Yu, Wu, Junlong, Pan, Jian, Freedland, Stephen J., Zheng, Ying, Ye, Dingwei

“…Prostate cancer is a global health problem, but incidence varies considerably across different continents. Asia is traditionally considered a low-incidence…”
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Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer by Fizazi, Karim, Tran, NamPhuong, Fein, Luis, Matsubara, Nobuaki, Rodriguez-Antolin, Alfredo, Alekseev, Boris Y, Özgüroğlu, Mustafa, Ye, Dingwei, Feyerabend, Susan, Protheroe, Andrew, De Porre, Peter, Kheoh, Thian, Park, Youn C, Todd, Mary B, Chi, Kim N

“…The addition of abiraterone, a drug that blocks endogenous androgen synthesis, to standard androgen-deprivation therapy in patients with newly diagnosed,…”
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Identification and Validation of Stromal Immunotype Predict Survival and Benefit from Adjuvant Chemotherapy in Patients with Muscle-Invasive Bladder Cancer by Fu, Hangcheng, Zhu, Yu, Wang, Yiwei, Liu, Zheng, Zhang, Junyu, Xie, Huyang, Fu, Qiang, Dai, Bo, Ye, Dingwei, Xu, Jiejie

“…This study aims to construct the stromal immunotype, which could improve the prediction of postsurgical survival and adjuvant platinum-based chemotherapy in…”
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Darolutamide and Survival in Metastatic, Hormone-Sensitive Prostate Cancer by Smith, Matthew R, Hussain, Maha, Saad, Fred, Fizazi, Karim, Sternberg, Cora N, Crawford, E. David, Kopyltsov, Evgeny, Park, Chandler H, Alekseev, Boris, Montesa-Pino, Álvaro, Ye, Dingwei, Parnis, Francis, Cruz, Felipe, Tammela, Teuvo L.J, Suzuki, Hiroyoshi, Utriainen, Tapio, Fu, Cheng, Uemura, Motohide, Méndez-Vidal, María J, Maughan, Benjamin L, Joensuu, Heikki, Thiele, Silke, Li, Rui, Kuss, Iris, Tombal, Bertrand

“…Standard therapy for metastatic, hormone-sensitive prostate cancer is androgen-deprivation therapy, usually with docetaxel. A large, multinational, phase 3…”
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A proteogenomic analysis of clear cell renal cell carcinoma in a Chinese population by Qu, Yuanyuan, Feng, Jinwen, Wu, Xiaohui, Bai, Lin, Xu, Wenhao, Zhu, Lingli, Liu, Yang, Xu, Fujiang, Zhang, Xuan, Yang, Guojian, Lv, Jiacheng, Chen, Xiuping, Shi, Guo-Hai, Wang, Hong-Kai, Cao, Da-Long, Xiang, Hang, Li, Lingling, Tan, Subei, Gan, Hua-Lei, Sun, Meng-Hong, Qiu, Jiange, Zhang, Hailiang, Zhao, Jian-Yuan, Ye, Dingwei, Ding, Chen

“…Clear cell renal cell carcinoma (ccRCC) is a common and aggressive subtype of renal cancer. Here we conduct a comprehensive proteogenomic analysis of 232 tumor…”
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Tislelizumab in Asian patients with previously treated locally advanced or metastatic urothelial carcinoma by Ye, Dingwei, Liu, Jiyan, Zhou, Aiping, Zou, Qing, Li, Hanzhong, Fu, Cheng, Hu, Hailong, Huang, Jian, Zhu, Shaoxing, Jin, Jie, Ma, Lulin, Guo, Jianming, Xiao, Jun, Park, Se Hoon, Zhang, Dahong, Qiu, Xiusong, Bao, Yuanyuan, Zhang, Lilin, Shen, Wei, Bi, Feng

“…Tislelizumab, an anti‐programmed death protein‐1 (PD‐1) monoclonal antibody, was engineered to minimize binding to the FcγR on macrophages to abrogate…”
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Long non-coding RNA LOC572558 inhibits bladder cancer cell proliferation and tumor growth by regulating the AKT–MDM2–p53 signaling axis by Zhu, Yiping, Dai, Bo, Zhang, Hailiang, Shi, Guohai, Shen, Yijun, Ye, Dingwei

“…Highlights • LOC572558 levels are down-regulated in bladder cancer. • Overexpression of LOC572558 inhibited bladder cancer cell proliferation and induced cell…”
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Constitutively Active AR-V7 Plays an Essential Role in the Development and Progression of Castration-Resistant Prostate Cancer by Qu, Yuanyuan, Dai, Bo, Ye, Dingwei, Kong, Yunyi, Chang, Kun, Jia, Zhongwei, Yang, Xiaoqun, Zhang, Hailiang, Zhu, Yao, Shi, Guohai

“…This study aimed to investigate the role of AR-V7 in development of castration-resistant prostate cancer (CRPC) and to determine whether the AR-V7 expression…”
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SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition by Ma, Jian, Shi, Qing, Cui, Gaofeng, Sheng, Haoyue, Botuyan, Maria Victoria, Zhou, Yingke, Yan, Yuqian, He, Yundong, Wang, Liguo, Wang, Yuzhuo, Mer, Georges, Ye, Dingwei, Wang, Chenji, Huang, Haojie

“…Geminin and its binding partner Cdt1 are essential for the regulation of DNA replication. Here we show that the CULLIN3 E3 ubiquitin ligase adaptor protein…”
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Prostate Cancer and Prostatic Diseases Best of Asia, 2019: challenges and opportunities by Zhu, Yao, Freedland, Stephen J., Ye, Dingwei

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A novel gene signature to predict immune infiltration and outcome in patients with prostate cancer by Shao, Ning, Tang, Hong, Mi, Yuanyuan, Zhu, Yao, Wan, Fangning, Ye, Dingwei

“…Prostate cancer (PCa) is one of the most common malignancies in male. We aim to establish a novel gene signature for immune infiltration and outcome…”
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Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression by Ren, Shancheng, Wei, Gong-Hong, Liu, Dongbing, Wang, Liguo, Hou, Yong, Zhu, Shida, Peng, Lihua, Zhang, Qin, Cheng, Yanbing, Su, Hong, Zhou, Xiuqing, Zhang, Jibin, Li, Fuqiang, Zheng, Hancheng, Zhao, Zhikun, Yin, Changjun, He, Zengquan, Gao, Xin, Zhau, Haiyen E., Chu, Chia-Yi, Wu, Jason Boyang, Collins, Colin, Volik, Stanislav V., Bell, Robert, Huang, Jiaoti, Wu, Kui, Xu, Danfeng, Ye, Dingwei, Yu, Yongwei, Zhu, Lianhui, Qiao, Meng, Lee, Hang-Mao, Yang, Yuehong, Zhu, Yasheng, Shi, Xiaolei, Chen, Rui, Wang, Yang, Xu, Weidong, Cheng, Yanqiong, Xu, Chuanliang, Gao, Xu, Zhou, Tie, Yang, Bo, Hou, Jianguo, Liu, Li, Zhang, Zhensheng, Zhu, Yao, Qin, Chao, Shao, Pengfei, Pang, Jun, Chung, Leland W.K., Xu, Jianfeng, Wu, Chin-Lee, Zhong, Weide, Xu, Xun, Li, Yingrui, Zhang, Xiuqing, Wang, Jian, Yang, Huanming, Wang, Jun, Huang, Haojie, Sun, Yinghao

“…Global disparities in prostate cancer (PCa) incidence highlight the urgent need to identify genomic abnormalities in prostate tumors in different ethnic…”
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Prognostic Value of Germline DNA Repair Gene Mutations in De Novo Metastatic and Castration‐Sensitive Prostate Cancer by Wei, Yu, Wu, Junlong, Gu, Weijie, Wang, Jun, Lin, Guowen, Qin, Xiaojian, Dai, Bo, Gan, Hualei, Ye, Dingwei, Zhu, Yao

“…Background Germline DNA damage repair gene mutations (gDDRm) have been found in approximately 12% of patients with metastatic prostate cancer (mPCa). Previous…”
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Tumor-associated macrophage-derived chemokine CCL5 facilitates the progression and immunosuppressive tumor microenvironment of clear cell renal cell carcinoma by Xu, Wenhao, Wu, Yuhao, Liu, Wangrui, Anwaier, Aihetaimujiang, Tian, Xi, Su, Jiaqi, Huang, Haineng, Wei, Gaomeng, Qu, Yuanyuan, Zhang, Hailiang, Ye, Dingwei

“…Tumor-associated macrophages (TAMs) dominate the malignancy of cancers by perturbing the tumor microenvironment (TME). However, the clinical implications of…”
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ALPK2 acts as tumor promotor in development of bladder cancer through targeting DEPDC1A by Wang, Yuchen, Wu, Jie, Luo, Wenjie, Zhang, Hailiang, Shi, Guohai, Shen, Yijun, Zhu, Yao, Ma, Chunguang, Dai, Bo, Ye, Dingwei, Zhu, Yiping

“…Bladder cancer is one of the most common malignant tumors in the urinary system. The development and improvement of treatment efficiency require the deepening…”
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Germline mutation of TSC1 or TSC2 gene in Chinese patients with bilateral renal angiomyolipomas and mutation spectrum of Chinese TSC patients by Jiangyi, Wang, Gang, Guo, Guohai, Shi, Dingwei, Ye

“…The germline mutation of the TSC1/2 gene in bilateral renal angiomyolipomas is unclear. Meanwhile, the mutation spectrum of Chinese TSC patients has not been…”
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CXCR6 expression predicts prognosis and immunotherapeutic benefit in muscle-invasive bladder cancer by Lu, Xiaolin, Ge, Li-Ping, Liu, Zhaopei, Zhu, Yu, Ye, Dingwei, Chang, Yuan

“…Background Increasing evidence suggests that the CXC chemokine receptor 6 (CXCR6) is involved in tumor progression and the regulation of tumor immunity…”
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Multi-omics reveals novel prognostic implication of SRC protein expression in bladder cancer and its correlation with immunotherapy response by Xu, Wenhao, Anwaier, Aihetaimujiang, Ma, Chunguang, Liu, Wangrui, Tian, Xi, Palihati, Maierdan, Hu, Xiaoxin, Qu, Yuanyuan, Zhang, Hailiang, Ye, Dingwei

“…This study aims to identify potential prognostic biomarkers of bladder cancer (BCa) based on large-scale multi-omics data and investigate the role of SRC in…”
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