Search Results - "Yazdanbakhsh, Maria"

Investigation of urinary metabolomics in a phase I hookworm vaccine trial in Gabon by Betouke Ongwe, Madeleine Eunice, Mouwenda, Yoanne D, Stam, Koen A, Kremsner, Peter G, Lell, Bertrand, Diemert, David, Bethony, Jeff, Bottazzi, Maria E, Hotez, Peter J, Leeuwen, Remko V, Grobusch, Martin P, Adegnika, Ayola A, Mayboroda, Oleg A, Yazdanbakhsh, Maria

“…Metabolomics provides a powerful tool to study physiological changes in response to various perturbations such as vaccination. We explored whether metabolomic…”
Get full text

Helminth therapy or elimination: epidemiological, immunological, and clinical considerations by Wammes, Linda J, MD, Mpairwe, Harriet, PhD, Elliott, Alison M, Prof, Yazdanbakhsh, Maria, Prof

“…Summary Deworming is rightly advocated to prevent helminth-induced morbidity. Nevertheless, in affluent countries, the deliberate infection of patients with…”
Get full text

Effects of schistosomes on host anti-viral immune response and the acquisition, virulence, and prevention of viral infections: A systematic review by Bullington, Brooke W, Klemperer, Katherine, Mages, Keith, Chalem, Andrea, Mazigo, Humphrey D, Changalucha, John, Kapiga, Saidi, Wright, Peter F, Yazdanbakhsh, Maria M, Downs, Jennifer A

“…Although a growing number of studies suggest interactions between Schistosoma parasites and viral infections, the effects of schistosome infections on the host…”
Get full text

Butyrate Conditions Human Dendritic Cells to Prime Type 1 Regulatory T Cells via both Histone Deacetylase Inhibition and G Protein-Coupled Receptor 109A Signaling by Kaisar, Maria M M, Pelgrom, Leonard R, van der Ham, Alwin J, Yazdanbakhsh, Maria, Everts, Bart

“…Recently, it has become clear that short-chain fatty acids (SCFAs), and in particular butyrate, have anti-inflammatory properties. Murine studies have shown…”
Get full text

Regulation of pathogenesis and immunity in helminth infections by Maizels, Rick M, Pearce, Edward J, Artis, David, Yazdanbakhsh, Maria, Wynn, Thomas A

“…Helminths are multicellular eukaryotic parasites that infect over one quarter of the world's population. Through coevolution with the human immune system,…”
Get full text

Regulatory B-cell induction by helminths: Implications for allergic disease by Hussaarts, Leonie, MSc, van der Vlugt, Luciën E.P.M., MSc, Yazdanbakhsh, Maria, PhD, Smits, Hermelijn H., PhD

“…Chronic helminth infections are often associated with a reduced prevalence of inflammatory disorders, including allergic diseases. Helminths influence the host…”
Get full text

Chronic helminth infections induce immunomodulation: Consequences and mechanisms by van Riet, Elly, Hartgers, Franca C, Yazdanbakhsh, Maria

“…Abstract Worldwide, more than a billion people are infected with helminths. These worm infections generally do not lead to mortality, however, they are chronic…”
Get full text

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome by Mathias, Rasika Ann, Taub, Margaret A., Gignoux, Christopher R., Fu, Wenqing, Musharoff, Shaila, O'Connor, Timothy D., Vergara, Candelaria, Torgerson, Dara G., Pino-Yanes, Maria, Shringarpure, Suyash S., Huang, Lili, Rafaels, Nicholas, Boorgula, Meher Preethi, Johnston, Henry Richard, Ortega, Victor E., Levin, Albert M., Song, Wei, Torres, Raul, Padhukasahasram, Badri, Eng, Celeste, Mejia-Mejia, Delmy-Aracely, Ferguson, Trevor, Qin, Zhaohui S., Scott, Alan F., Yazdanbakhsh, Maria, Wilson, James G., Marrugo, Javier, Lange, Leslie A., Kumar, Rajesh, Avila, Pedro C., Williams, L. Keoki, Watson, Harold, Ware, Lorraine B., Olopade, Christopher, Olopade, Olufunmilayo, Oliveira, Ricardo, Ober, Carole, Nicolae, Dan L., Meyers, Deborah, Mayorga, Alvaro, Knight-Madden, Jennifer, Hartert, Tina, Hansel, Nadia N., Foreman, Marilyn G., Ford, Jean G., Faruque, Mezbah U., Dunston, Georgia M., Caraballo, Luis, Burchard, Esteban G., Bleecker, Eugene, Araujo, Maria Ilma, Herrera-Paz, Edwin Francisco, Gietzen, Kimberly, Grus, Wendy E., Bamshad, Michael, Bustamante, Carlos D., Kenny, Eimear E., Hernandez, Ryan D., Beaty, Terri H., Ruczinski, Ingo, Akey, Joshua, Barnes, Kathleen C.

“…The African Diaspora in the Western Hemisphere represents one of the largest forced migrations in history and had a profound impact on genetic diversity in…”
Get full text

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor by Everts, Bart, Hussaarts, Leonie, Driessen, Nicole N, Meevissen, Moniek H J, Schramm, Gabriele, van der Ham, Alwin J, van der Hoeven, Barbara, Scholzen, Thomas, Burgdorf, Sven, Mohrs, Markus, Pearce, Edward J, Hokke, Cornelis H, Haas, Helmut, Smits, Hermelijn H, Yazdanbakhsh, Maria

“…Omega-1, a glycosylated T2 ribonuclease (RNase) secreted by Schistosoma mansoni eggs and abundantly present in soluble egg antigen, has recently been shown to…”
Get full text

Helminth infections, type-2 immune response, and metabolic syndrome by Wiria, Aprilianto E, Sartono, Erliyani, Supali, Taniawati, Yazdanbakhsh, Maria

“…  The Association between Metabolic Syndrome and Inflammation Metabolic syndrome (MetS), a disorder of energy utilization and storage, manifests as a cluster…”
Get full text

Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses by Everts, Bart, Perona-Wright, Georgia, Smits, Hermelijn H, Hokke, Cornelis H, van der Ham, Alwin J, Fitzsimmons, Colin M, Doenhoff, Michael J, van der Bosch, Jürgen, Mohrs, Katja, Haas, Helmut, Mohrs, Markus, Yazdanbakhsh, Maria, Schramm, Gabriele

“…Soluble egg antigens of the parasitic helminth Schistosoma mansoni (S. mansoni egg antigen [SEA]) induce strong Th2 responses both in vitro and in vivo…”
Get full text

Influenza in Africa by Yazdanbakhsh, Maria, Kremsner, Peter G

“…Maria Yazdanbakhsh and Peter Kremsner argue that there needs to be better awareness, surveillance, and clinical management of common febrile diseases in…”
Get full text

Differential human gut microbiome assemblages during soil-transmitted helminth infections in Indonesia and Liberia by Rosa, Bruce A, Supali, Taniawati, Gankpala, Lincoln, Djuardi, Yenny, Sartono, Erliyani, Zhou, Yanjiao, Fischer, Kerstin, Martin, John, Tyagi, Rahul, Bolay, Fatorma K, Fischer, Peter U, Yazdanbakhsh, Maria, Mitreva, Makedonka

“…The human intestine and its microbiota is the most common infection site for soil-transmitted helminths (STHs), which affect the well-being of ~ 1.5 billion…”
Get full text

Controlled human hookworm infection remodels plasmacytoid dendritic cells and regulatory T cells towards profiles seen in natural infections in endemic areas by Manurung, Mikhael D., Sonnet, Friederike, Hoogerwerf, Marie-Astrid, Janse, Jacqueline J., Kruize, Yvonne, Bes-Roeleveld, Laura de, König, Marion, Loukas, Alex, Dewals, Benjamin G., Supali, Taniawati, Jochems, Simon P., Roestenberg, Meta, Coppola, Mariateresa, Yazdanbakhsh, Maria

“…Hookworm infection remains a significant public health concern, particularly in low- and middle-income countries, where mass drug administration has not…”
Get full text

Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia by Martin, Ivonne, Djuardi, Yenny, Sartono, Erliyani, Rosa, Bruce A, Supali, Taniawati, Mitreva, Makedonka, Houwing-Duistermaat, Jeanine J, Yazdanbakhsh, Maria

“…Microbiome studies suggest the presence of an interaction between the human gut microbiome and soil-transmitted helminth. Upon deworming, a complex interaction…”
Get full text

Immunological Considerations for Schistosoma Vaccine Development: Transitioning to Endemic Settings by Driciru, Emmanuella, Koopman, Jan Pieter R, Cose, Stephen, Siddiqui, Afzal A, Yazdanbakhsh, Maria, Elliott, Alison M, Roestenberg, Meta

“…Despite mass drug administration programmes with praziquantel, the prevalence of schistosomiasis remains high. A vaccine is urgently needed to control…”
Get full text

Current status of schistosomiasis in school-aged children in Mwanga district, Tanzania: impact of two decades of annual Mass Drug Administration programme by Pyuza, Jeremia J, Meulah, Brice, Hoekstra, Pytsje T, Mdende, Noel, Mvilli, Elizabeth, Lieshout, Lisette van, Hilt, Stan T, Corstjens, Paul L A M, Yazdanbakhsh, Maria, Msuya, Sia E, van Dam, Govert J

“…Schistosomiasis is a neglected tropical disease with significant health implications, particularly among children. A cross-sectional study was conducted among…”
Get full text

Investigation of urinary metabolomics in a phase I hookworm vaccine trial in Gabon by Madeleine Eunice Betouke Ongwe, Yoanne D Mouwenda, Koen A Stam, Peter G Kremsner, Bertrand Lell, David Diemert, Jeff Bethony, Maria E Bottazzi, Peter J Hotez, Remko V Leeuwen, Martin P Grobusch, Ayola A Adegnika, Oleg A Mayboroda, Maria Yazdanbakhsh

“…Metabolomics provides a powerful tool to study physiological changes in response to various perturbations such as vaccination. We explored whether metabolomic…”
Get full text

Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells by van der Vlugt, Luciën E P M, Labuda, Lucja A, Ozir-Fazalalikhan, Arifa, Lievers, Ellen, Gloudemans, Anouk K, Liu, Kit-Yeng, Barr, Tom A, Sparwasser, Tim, Boon, Louis, Ngoa, Ulysse Ateba, Feugap, Eliane Ngoune, Adegnika, Ayola A, Kremsner, Peter G, Gray, David, Yazdanbakhsh, Maria, Smits, Hermelijn H

“…Chronic helminth infections, such as schistosomes, are negatively associated with allergic disorders. Here, using B cell IL-10-deficient mice, Schistosoma…”
Get full text

S. mansoni -derived omega-1 prevents OVA-specific allergic airway inflammation via hampering of cDC2 migration by Patente, Thiago A, Gasan, Thomas A, Scheenstra, Maaike, Ozir-Fazalalikhan, Arifa, Obieglo, Katja, Schetters, Sjoerd, Verwaerde, Stijn, Vergote, Karl, Otto, Frank, Wilbers, Ruud H P, van Bloois, Eline, Wijck, Yolanda van, Taube, Christian, Hammad, Hamida, Schots, Arjen, Everts, Bart, Yazdanbakhsh, Maria, Guigas, Bruno, Hokke, Cornelis H, Smits, Hermelijn H

“…Chronic infection with Schistosoma mansoni parasites is associated with reduced allergic sensitization in humans, while schistosome eggs protects against…”
Get full text